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Targeting Chronic Inflammatory Lung
Diseases Using Advanced Drug Delivery S

Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems

Principles and Practice

Cement Production Technology

Nanobiotechnology for Clinical Adoptability and Application offers an overview of medical bioanalysis and biotechnological application in diagnostics and therapeutics. The book discusses modern concepts and bioanalytical methodologies in nanoscience and nanobiotechnology, and their integration in real-time point-of-care applications which has emerged as a significant area of biomedical research. The book explores medical diagnostic use of different imaging and biosensing technologies including biochemical methods, electrochemical sensors to detect infectious diseases, and microfluidics-based bioanalytical systems. It also covers biotechnological approaches to experimental therapeutics and theragnostics. Ethical and regulatory considerations in biomedicine and medical diagnostics round out the coverage making Nanobiotechnology for Clinical Adoptability and Application a valuable resource for researchers, faculty, post-graduate students and professionals in biotechnology, biochemistry, nanotechnology, biomedical engineering, medicine, pharmaceutical sciences, or any related biomedical discipline.

Nanobiotechnology for Clinical Adoptability and Application

Artificial Intelligence in Precision Drug Design, Volume One: Foundations and Core Techniques offers a comprehensive introduction to the transformative role of AI in modern drug discovery. The book lays the groundwork for understanding how machine learning, deep learning, and generative models are reshaping the development of precision therapeutics. It explores foundational topics such as AI-driven molecular screening, pharmacokinetics, ADMET modeling, toxicity prediction, and omics integration. In addition, sections address ethical, philosophical, and epistemological dimensions, ensuring a well-rounded perspective. Each chapter, authored by global experts, combines theoretical insights with real-world case studies to bridge the gap between AI and life sciences. Designed for graduate students, researchers, and professionals in bioinformatics, biomedical sciences, and pharmaceutical R&amp;D, this volume equips readers with essential knowledge and tools to navigate the evolving landscape of AI in drug design. It empowers interdisciplinary learners to apply cutting-edge AI techniques to real-world biomedical challenges.

Foundations and Core Techniques

Artificial Intelligence in Precision Drug Design, Volume 1

A road map for developing responsible and innovative governance systems based on generative AI and other exponential technologiesAs exponential technology rapidly advances, leaders in every sector are faced with the challenge of harnessing its potential power while developing precautionary safeguards against its risks. From generative artificial intelligence to the future of quantum computing, these innovations are transforming the world at an unprecedented rate, leaving decision-makers unsure of how to maintain control and ensure responsible development.Governing Pandora focuses on multiple exponential technologies in order to demonstrate how leaders can develop responsible and innovative governance systems. This book equips leaders with frameworks and tools-including a detailed five-element "exponential governance mind-set"--to develop a more holistic tech governance approach for current and future waves of exponential tech. Andrea Bonime-Blanc encourages the development of a culture of collaboration across borders, sectors, and disciplines as technology takes on a bigger role in our ecosystem. She explains the context, risks, and opportunities of the ongoing exponential technology revolution so that leaders can futureproof themselves, their organizations, and key stakeholders with strategies and tactics to act responsibly, ethically, and successfully.This book speaks directly to executives, board members, policymakers, and organizational leaders who are tasked with charting a course through the advancement of modern technologies. Governing Pandora bridges the gap between exploring pure technology and managing and governing applied technology. Readers will learn not only how to develop a governance mind-set for exponential technology but also how to build organizational resilience.

Leading in the Age of Generative AI and Exponential Technology

Governing Pandora

Advances in Medical Imaging: From Behavioral Analysis to Disease Prevention and Rehabilitation presents a comprehensive exploration of the rapidly evolving field of medical imaging at the crossroads of clinical science, behavioral research, and public health. This book addresses the growing need to understand how advanced imaging technologies-such as MRI, PET, and ultrasound-are transforming healthcare beyond traditional diagnosis. By capturing structural, functional, metabolic, and molecular processes, these innovations provide new insights into brain function, lifestyle impacts, chronic disease, and rehabilitation, supporting the shift toward personalized and preventive medicine. The book is organized into five thematic sections covering a wide range of topics. Early chapters focus on the integration of neuroimaging with behavioral science, highlighting brain-behavior relationships through cutting-edge imaging modalities and cognitive software. Subsequent sections examine the effects of sedentary lifestyles on brain health, vascular function assessed by ultrasound, and musculoskeletal aging through imaging biomarkers. Additional chapters explore chronic disease management, yoga and cognitive well-being, stroke recovery, traumatic brain injury rehabilitation, and the expanding role of imaging in oncology and systemic diseases. Throughout, the book emphasizes the use of artificial intelligence, radiomics, and multimodal imaging to enhance precision medicine and population health research. Advances in Medical Imaging: From Behavioral Analysis to Disease Prevention and Rehabilitation offers valuable insights for researchers, clinicians, and healthcare professionals interested in the applications of medical imaging across multiple disciplines. It highlights imaging’s critical role in advancing personalized care, supporting preventive strategies, and fostering innovation in modern healthcare.

From Behavioural Analysis to Disease Prevention and Rehabilitation

Advances in Medical Imaging

Previously known as Drafting Agreements in the Biotechnology and Pharmaceutical Industries, this title provides precedent agreements for the main types of commercial transaction encountered in the life sciences, biotechnology and pharmaceutical industries. In addition to the print version, each precedent is available via an accompanying website in a format which can be easily downloaded and edited. Detailed commentary on legal, commercial and practice issues accompanies every precedent. Provided by specialist lawyers from across Europe, this commentary also highlights important differences between English law and that of other key EU jurisdictions: Germany, France, the Netherlands, Spain and Sweden. Commentary on specific considerations for the US is also provided. In addition to precedent commentaries, the book also contains detailed commentary and discussion of legal issues common to the life sciences, biotechnology and pharmaceutical industries, as well as links to relevant materials (eg regulatory materials on clinical trials). This title is included in Bloomsbury Professional's Intellectual Property and IT online service.

Drafting Agreements in Life Sciences

Targeting Intercellular Communication with Nanomedicine and Advanced Therapeutics delves into the complex world of intercellular communication biology and its implications on therapeutics. This book covers all areas of intercellular communication and therapeutics in development for different forms of communication, including their role in diseases such as cancer, neurological disorders, metabolic diseases, and inflammatory/immune diseases. Sections provide an introduction, biological targets, challenges, and approaches to overcoming biological barriers and the significance of contact points and mechanisms of internalization. Specifics of tunneling nanotubes, extracellular vesicles, and the immune and non-immune interface in various diseases are covered. Furthermore, the book explores the crosstalk of different forms of intercellular communication and the implications of mitochondrial exchange in the four primary pathological areas. This is an essential resource for researchers, students, and professionals in the field of drug development and delivery. By connecting the dots between extracellular vesicles, tunneling nanotubes, and cell-cell junctions, this book serves as a foundation for further advancements in the science of intercellular communication and it's applications to new drug discovery and delivery.

Targeting Intercellular Communication with Nanomedicine and Advanced Therapeutics

The inside story of the race to develop Ozempic - the world's first truly effective and safe obesity drug - and its potentially revolutionary effects on public health, and our deeper culture and values.'A FASCINATING DEEP DIVE' Guardian'VERY ENGAGING' New Scientist'ENLIGHTENING' Publishers WeeklyA 'cure' for obesity has long evaded the pharmaceutical industry, until the development of Ozempic: a diabetes medication that targets the GLP-1 hormone and makes people feel fuller for longer.After decades of research, Ozempic's creator Novo Nordisk quickly became one of the most valuable companies in Europe. Now it struggles to keep up with its rivals in an explosive and lucrative market for weight-loss injections. The treatment is so effective that it's already disrupted industries from healthcare to fast food to fashion. Financial investment has skyrocketed and public demand continues to soar alongside celebrity endorsements. Beyond million-dollar profits, countless lives could now be saved from preventable diseases, but one question remains: are these drugs too good to be true?Through original reporting and rigorous research, Aimee Donnellan uncovers the complicated history of a medical breakthrough that is changing the world, while raising difficult questions about inequality, morality, our beauty ideals and the pursuit of thinness. Along the way, Donnellan profiles the female scientist whose contributions to the discovery of GLP-1 were overlooked and some of the earliest Ozempic users share powerful testimonies.Off the Scales is a revelatory, gripping and urgent study of the unexpected consequences of finally getting what we've wanted for so long.'A lively tale of the stunning rise of Ozempic. This detailed, eye-opening account is bolstered by an insider look at commercial drug development' Irish Times'The definitive account of a singular global force - essential reading to help us understand what has been unleashed and what may be coming next' Andy Slavitt, author of Preventable'[A] Meticulously reported account ... and it is done very well - briskly and brightly ... Donnellan has performed a public service by taking down the first draft of history: by speaking to the main players and untangling the rivalries and disputes' The Times'A riveting read ... Donnellan captures the drama behind the science ... and explores the wider implications for society, health and business in this deeply researched book' John Collingridge, Guardian business editor

The Inside Story of Ozempic and the Race to Cure Obesity

Off the Scales

Roadmap to Successful Digital Health Ecosystems: A Global Perspective, Second Edition, explores the transformative integration of digital health technologies to enhance healthcare delivery and patient outcomes. This book provides a comprehensive overview of the evolving landscape of digital health, focusing on next-generation systems and the role of artificial intelligence in creating efficient healthcare ecosystems. The revised content covers topics such as regional implementation experiences, workforce management, and precision healthcare. New chapters highlight advancements in digital health technologies, case studies from Jamaica and Africa, and strategies for addressing fragmentation in healthcare systems. The book emphasizes ethical AI use and proactive, integrated healthcare approaches. For the academic audience, this revision serves as an essential resource, compiling cutting-edge research and practical applications that inform best practices in digital health. It equips researchers, educators, and practitioners with the knowledge needed to navigate the complexities of digital health ecosystems and drive innovation in their fields.

A Global Perspective

Roadmap to Successful Digital Health Ecosystems

Drug Targeting Complexity: Tissue-Specific Regulation and Molecular Paradigms in Cancer Therapy presents a rigorous examination of advanced strategies for the selective targeting of neoplastic cells and their distinct microenvironments. This comprehensive volume elucidates both tissue-specific and tumor-specific molecular targets, clarifying how these methodologies can significantly enhance therapeutic precision while mitigating off-target effects. The initial section of the text provides an in-depth analysis of tissue-specific regulatory targets across various organs, including the liver, lungs, brain, skin, and bones. It delineates the critical mediators and mechanisms that govern tumor immunity, thereby identifying novel therapeutic avenues. Each chapter meticulously evaluates key regulatory molecules such as TGF-β, CTLA-4, and IL-10, exploring their roles in tumorigenesis and the potential for targeted interventions across a spectrum of malignancies. The subsequent sections focus on tumor tissue-specific molecular targets, encompassing immunological checkpoints, growth factors, and signaling pathways pertinent to cancers of the liver, stomach, ovary, prostate, and colon. The text provides insights into the application of monoclonal antibodies and molecular inhibitors as strategies to impede cancer progression and address therapeutic resistance. In its concluding chapters, the volume addresses emerging therapeutic paradigms, including precision medicine and nanotechnology, emphasizing their capacity to refine drug delivery systems and customize therapeutic regimens based on individual genetic and molecular profiles. This academic reference is intended for pharmaceutical scientists, pharmacologists, and oncologists seeking a comprehensive understanding of targeted cancer therapeutics, thereby establishing a foundation for the next generation of oncological treatments aimed at optimizing patient outcomes through personalized, precision-based methodologies.

Tissue-Specific Regulation and Molecular Paradigms in Cancer Therapy

Drug Targeting Complexity

De Gruyter Reference

The present book is part of series published on Spectrophotometric methods for determination of various chemical elements. Since rare earth elements are most important industrial chemical elements their analysis using simple and inexpensive methods is of utmost importance. The present book is an important milestone in this area. Most of the methods described are simple yet well evidenced developed by the experts of the area. The book is written in do it yourself style in lucid and comprehensive way so that analyst with no prior expertise can use it. Academia and industry sector analyst will be true beneficiaries of this book.

The present book is part of series published on Spectrophotometric methods for determination of various chemical elements. Since rare earth elements are most important industrial chemical elements their analysis using simple and inexpensive methods is of utmost importance. The present book is an important milestone in this area. Most of the methods described are simple yet well evidenced developed by the experts of the area. The book is written in do it yourself style in lucid and comprehensive way so that analyst with no prior expertise can use it. Academia and industry sector analyst will be true beneficiaries of this book.

Reagents and Methods

Spectrophotometric Determination of Rare Earth Elements

Innovative Nanocarriers for Stimulated Drug Delivery: A Comprehensive Guide to Stimuli-responsive Nanoparticles summarizes recent advances and achievements in nanocarriers responsive to external or internal stimuli. The book presents different stimuli-sensitive strategies and their applications in drug delivery, therapy, and theranostics. Sections provide fundamental knowledge on the experiential and experimental aspects of stimuli-responsive nanocarriers, discuss external-responsive nanocarriers for biomedical applications, such as ultrasound, thermal, magnetic, light, and electric field-response systems, and describe internal stimuli-responsive nanocarriers for biomedical applications, including pH, hypoxia, redox potential, enzyme, glucose, and microRNA-responsive nanocarriers. Additionally, the book covers dual and multimodal-responsive nanocarriers and the therapeutic aspects of stimuli-responsive nanocarriers, such as metallic and non-metallic stimuli-responsive nanocarriers in the treatment of various cancer and noncancerous diseases. Finally, recent advances and regulatory aspects of stimuli-responsive nanocarriers, including clinical translation, challenges, biological toxicity, safety issues, clinical trials, and future perspectives are covered.

A Comprehensive Guide to Stimuli-responsive Nanoparticles

Innovative Nanocarriers for Stimulated Drug Delivery

Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems

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