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Pal A: Mitochondrial Genomics in Health
and Diseases

Mitochondrial Genomics in Health and Diseases

Transformation from Globular Proteins to Amyloids

Simulating Protein Folding in Variable Environmental Conditions

Matters of the Image introduces a new framework for thinking about digital images.

Matters of the Image introduces a new framework for thinking about digital images.

Designing Digital Images with Materiality, Energy, and Living Matter

This book will fill a need among animal paleopathologists and animal forensic scientists for a text/atlas focused on lesions that commonly appear in skeletal remains. The text describes what is known about disease pathogenesis and occurrence in modern and historical settings and include evolutionary and comparative considerations. It is a stand-alone atlas on animal bone disease with images of lesions on the whole bone, which would facilitate understanding of bone disease and provide insights into disease processes. This book fills a unique niche - a text/atlases on comparative bone pathology that includes images of whole specimens.

This book will fill a need among animal paleopathologists and animal forensic scientists for a text/atlas focused on lesions that commonly appear in skeletal remains. The text describes what is known about disease pathogenesis and occurrence in modern and historical settings and include evolutionary and comparative considerations. It is a stand-alone atlas on animal bone disease with images of lesions on the whole bone, which would facilitate understanding of bone disease and provide insights into disease processes. This book fills a unique niche - a text/atlases on comparative bone pathology that includes images of whole specimens.Key selling features:<ul> <li>Illustrates lesions in animal skeletal remains - no other such reference exists</li> <li>Reviews the basic pathology and pathogenesis of animal bone diseases</li> <li>Provides a source of information on the historical and modern contexts associated with the occurrence of animal bone diseases</li> <li>Describes evolutionary susceptibilities of bone disease in animals</li> <li>Examines human comparative aspects of bone disease in animals</li> </ul>

Pathological Conditions in Animal Skeletal Remains

Species and Systematics

A goal of macroevolutionary theory is to explain both diversity and disparity - different sometimes uncorrelated characteristics of lineages. These actively researched questions, the growing number of case studies, and the increasingly rigorous theory, has resulted in the re-examination of classical models for evolutionary tempo and mode. Time-calibrated molecular phylogenies are now used in conjunction with quantitative analyses of morphology to evaluate models of evolution. For example, mathematically simple efforts to understand biologically complex traits (such as body size) are common. The major objective of the proposed work is to present novel methods and case-studies of the tempo and mode of evolution of complex morphologies. Recent innovations in methods for describing and modeling complex morphologies, which have the potential to advance the field still further, will be the primary focus of this intended volume.

A goal of macroevolutionary theory is to explain both diversity and disparity. These actively researched questions, the growing number of case studies, and the increasingly rigorous theory, has resulted in the re-examination of classical models for evolutionary tempo and mode. Time-calibrated molecular phylogenies are now used in conjunction with quantitative analyses of morphology to evaluate models of evolution. This book will present novel methods and case-studies of the tempo and mode of evolution of complex morphologies, including recent innovations in methods for describing and modeling complex morphologies, which have the potential to advance the field still further.Key selling features:<ul> <li>Explores the relationship, if any, between species diversity and morphological disparity</li> <li>Includes relevant case studies</li> <li>Documents the role of geography and ecology in generating or retarding diversity and disparity</li> <li>Evaluates contingent, deterministic and intrinsic controls on macroevolutionary patterns</li> <li>Reviews models that predict diversity and disparity</li> </ul>

Macroevolution of Complex Morphologies

International Texts in Developmental Psychology

Insights from Genetics and Epigenetics

PSYCHOBIOLOGICAL DEVELOPMENT

How One Ancient Language Went Global

Proto

Practical Bioinformatics

Their Complexity, Fragility and Future

Coral Reefs

Globally, there are numerous infectious diseases, normally found in vertebrates other than humans, that have been documented to be transmitted to humans and cause human infections. These "zoonotic infections" are the topic of this book.This book is arranged to have chapters by the type of animal. Within each chapter is information on the animal(s), the normal flora of the animal(s), and the diseases that have been transmitted from this group of animals by bites and/or scratches, contact (including transmission via ectoparasites such as fleas and ticks), ingestion of the animal, and other documented transmission, such as infestation by members of the genus Sarcoptes as has been documented in humans exposed to dogs with "mange," in "cavalryman itch" from horses, from contact with dromedaries, etc.There are a number of additional issues that takeoff from a fundamental knowledge of zoonotic infections. These include a working knowledge of many of the agends of bioterrorism, as the events of 2001 demonstrated of the use of Bacillus anthracis spores in mailed letters. Another area of importance is that of emerging infections. An analysis of 335 origins of emerging infectious diseases between 1940 and 2004 revealed that these are dominated by infections that are zoonotic in origin, comprising some 60.3% of the emerging infections. Of these, 71.8% originated in wildlife.Given the importance of this topic in our understanding of infectious disease, a timely source is a necessary addition to the current available literature

Zoonoses: Animal Exposure and Human Disease

Genomic and Precision Medicine in Clinical Practice

Medical and Health Genomics of South Asia, a new volume in the Genomic and Precision Medicine in Clinical Practice series, offers a thorough discussion of medical genomics as applied across South Asian nations, from India to Pakistan, Bangladesh, Sri Lanka, and Nepal, as well as in South Asian populations abroad. Here, global chapter authors consider genomic variation and the population heterogeneity of genetic, infectious, and lifestyle diseases in South Asia, along with successful modes of population health management for these inherited disorders and other applications of clinical genomics for improved individual health in the region. Adopting an applied approach, this book first reviews basic genomic models and population study formats, as well as the anthropological and genetic history of South Asia. The following sections examine genomic epidemiology and population health in the South Asian context; examples of genomic medicine's use in combating major health challenges in the region; genomic healthcare infrastructure; and related social, ethical, legal, and economic aspects central to impactful genomic medicine.

Medical and Health Genomics of South Asia

Structural Biology of Amyloid Fibrils is a comprehensive reference on the structure of protein aggregates in different neurodegenerative diseases and their molecular bases. Chapters describe these structures in detail, highlighting their similarities and differences across different disease states, alongside an unprecedented overview of current developments and new hypotheses emerging in amyloid fibril structure, stability and mechanisms of formation. This volume also discusses how amyloid structure may affect the ability of fibrils to spread to different sites in a prion-like manner, as well as their role in disease. Featuring chapters on NMR, X-ray crystallography, and Cryo-EM methods, and discussing the structure of amyloid fibrils obtained directly from patients, the book allows readers to understand how polymorphism is associated with disease phenotype and how fibril structure affects and influences the cellular environment. Understanding the molecular architecture of amyloid fibrils and oligomers will be an important step towards developing therapeutic interventions based on targeting the fibrils and oligomers themselves, or the processes that generate them.

Structural Biology of Amyloid Fibrils

Concepts, Techniques, Applications, and Achievements

Probiogenomics and Probiomics

Mitochondrial Genomics in Health and Diseases

Bibliografische Angaben

Schlagworte

Bibliografische Angaben

Schlagworte

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