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Probiogenomics and Probiomics

Concepts, Techniques, Applications, and Achievements

Genomic and Precision Medicine in Clinical Practice

Medical and Health Genomics of South Asia, a new volume in the Genomic and Precision Medicine in Clinical Practice series, offers a thorough discussion of medical genomics as applied across South Asian nations, from India to Pakistan, Bangladesh, Sri Lanka, and Nepal, as well as in South Asian populations abroad. Here, global chapter authors consider genomic variation and the population heterogeneity of genetic, infectious, and lifestyle diseases in South Asia, along with successful modes of population health management for these inherited disorders and other applications of clinical genomics for improved individual health in the region. Adopting an applied approach, this book first reviews basic genomic models and population study formats, as well as the anthropological and genetic history of South Asia. The following sections examine genomic epidemiology and population health in the South Asian context; examples of genomic medicine's use in combating major health challenges in the region; genomic healthcare infrastructure; and related social, ethical, legal, and economic aspects central to impactful genomic medicine.

Medical and Health Genomics of South Asia

Biotic Stress Tolerance in Horticultural Crops: Challenges and Mitigation Strategies explores concepts, strategies, and recent advancements in the area of biotic stress tolerance in horticultural crops, highlighting the latest advances in molecular breeding, genome sequencing, and functional genomics approaches. The book highlights a variety of aspects of biotic stress tolerance in horticultural crops, from classical breeding, hybrid breeding, speed breeding, epigenetics, gene/quantitative trait loci (QTL) mapping, transgenics, physiological and biochemical approaches to OMICS approaches, including functional genomics, proteomics, and genomics assisted breeding. This volume has been designed to include the advancements mitigating the effects of bacterial, viral, fungal, and insects-pests. Readers will find this to be a comprehensive resource for anyone working in the field of biotic stress management in horticultural crops, including students, educators, and scientists in industry and academia.

Challenges and Mitigation Strategies

Biotic Stress Tolerance in Horticultural Crops

Plant Biology, sustainability and climate change

Synergistic Plant Metabolomics and Plant Growth-Promoting Microorganisms in Addressing Abiotic Stress

Debating the use of genomic tools and their societal impactOver the past decade, the field of human genetics has produced an extraordinary range of discoveries-including the refinement of polygenic scores, which use a person's DNA to estimate their likelihood of developing a trait or disease. But are these new technologies ready to leave the research lab and be deployed in schools, fertility clinics, and the wider world? In What We Inherit, Sam Trejo and Daphne Martschenko offer different perspectives on the societal impact of the rapidly unfolding DNA revolution. Trejo, a sociologist and expert on the complex ways people's genes influence their life's trajectory, believes that new genomic tools-if used thoughtfully-can improve society; Martschenko, a bioethicist who specializes in the thorny social issues raised by biomedical advances, is more cautious. They debate both the risks and the opportunities posed by such new technologies as at-home genetic tests and polygenic embryo selection-all while engaging in a wide-ranging dialogue on ideology, biology, and social inequality. While grappling with these new technologies, Trejo and Martschenko remind us that we inherited from our ancestors not only DNA but also wrong-headed ideas about genes. Together, they caution against two particularly harmful genetic myths: that genes determine an individual's future, and that race and genetics are inherently connected. A polygenic score, for example, is not a definitive marker for disease. And race is a sociopolitical construct, not a biological identity. Trejo and Martschenko argue that, to avoid exacerbating social inequality, we need to begin regulating genomic tools sooner rather than later.

How New Technologies and Old Myths Are Shaping Our Genomic Future

What We Inherit

Translational Epigenetics

Lifestyle Epigenomics, a new volume in the Translational Epigenetics series, comprehensively details the interplay between lifestyle factors and epigenetic modifications associated with the onset of noncommunicable diseases and aging, shedding light on potential preventive and therapeutic strategies for disease from an epigenomics perspective. Here, more than 35 international experts in the field consider how lifestyle choices or habits can condition or prevent disease, along with tools for new research, from bioinformatics methodology to non-invasive sampling. Early, foundational chapters are followed by all-inclusive sections on epigenetic machinery in health and disease; dietary factors and epigenetics; adiposity and physical activity and epigenetics; psychological stress, social environment, toxins and contaminants exposure effects on epigenetics; and transgenerational and childhood epigenetics. To support understanding, each chapter includes a summary and key points lists, terms and definition, as well as research case studies outlining core components of recent studies, detailing their conditions, research techniques involved, and outcomes.

Lifestyle Epigenomics

International Texts in Developmental Psychology

Insights from Genetics and Epigenetics

PSYCHOBIOLOGICAL DEVELOPMENT

Advances in Cancer Research

Cerebral Metastases: Translational Advances, Evaluation and Management: Volume 165

Translational and Applied Genomics

Raising Genomics Literacy, Knowledge, and Awareness is a unique resource which describes the importance of genomic literacy for the effective and streamlined implementation of genomic medicine and pharmacogenomics globally. It provides evidence and expert opinion to decipher the role of genomic and pharmacogenomic literacy to illustrate the evidence, value, and need of raising genomics awareness and education among healthcare professionals, students, and the general public. This text can be used by researchers and graduate students pursuing research in this area.

Raising Genomics Literacy, Knowledge, and Awareness

Progress in Molecular Biology and Translational Science

Non-coding RNA: Volume 214

Nanomaterial-Plant Interactions

Nanomaterials for Enhanced Plant-Based Food Production a new release in the Nanomaterial-Plant Interactions series, presents up-to-date insights on the use of nano-enabled agricultural tools from nanofertilizers to nanosensors, including how to balance safety and environmental impact concerns to ensure optimal utilization. The book provides a range of solution options and guides the reader in identifying the most appropriate choice. With state-of-the-art, broad coverage of recent and potential applications, this book covers the most recent advances in the application of nanotechnology toward fulfilling the world's food demands for present and future generations.

Nanomaterials for Enhanced Plant-Based Food Production

New York Times bestselling author and former FDA Commissioner Scott Gottlieb provides a glimpse of a promising future that is quickly approaching: a world with cures for chronic illnesses and cancers. While traditional drugs mostly help us manage the effects of disease, cell therapies promise genuine cures for a broad range of intractable ailments, from Alzheimer's to heart damage to cancer. They could even reverse the effects of aging. For the first time in history, on an unprecedented scale, we possess the power to modify the biology that gives rise to disease, ultimately restoring individuals to a state of normalcy and reversing debilitating ailments. In The Miracle Century, former FDA Commissioner Scott Gottlieb traces the scientific achievements that propelled progress in cell therapies. The birth of this medical revolution wasn't a sudden event. Rather, it emerged from decades of steady, incremental progress in science. These concerted advances made cell therapies a reality. To forge a path for continued medical breakthroughs, Dr. Gottlieb meticulously traces this scientific journey, identifying lessons on how these achievements can be replicated. The MIracle Century is a look at the future of healthcare from one of the nation's leading medical authorities. Scott Gottlieb explains how these new medicines are moving from the laboratory bench to the marketplace and tackles the issues that must be addressed to enable wide adoption of these treatments and transform as many lives as possible.

New York Times bestselling author and former FDA Commissioner Scott Gottlieb provides a glimpse of a promising future that is quickly approaching: a world with cures for chronic illnesses and cancers.While traditional drugs mostly help us manage the effects of disease, cell therapies promise genuine cures for a broad range of intractable ailments, from Alzheimer’s to heart damage to cancer. They could even reverse the effects of aging. For the first time in history, on an unprecedented scale, we possess the power to modify the biology that gives rise to disease, ultimately restoring individuals to a state of normalcy and reversing debilitating ailments.In The Miracle Century, former FDA Commissioner Scott Gottlieb traces the scientific achievements that propelled progress in cell therapies. The birth of this medical revolution wasn’t a sudden event. Rather, it emerged from decades of steady, incremental progress in science. These concerted advances made cell therapies a reality. To forge a path for continued medical breakthroughs, Dr. Gottlieb meticulously traces this scientific journey, identifying lessons on how these achievements can be replicated.The MIracle Century is a look at the future of healthcare from one of the nation’s leading medical authorities. Scott Gottlieb explains how these new medicines are moving from the laboratory bench to the marketplace and tackles the issues that must be addressed to enable wide adoption of these treatments and transform as many lives as possible.

Making Sense of the Cell Therapy Revolution

The Miracle Century

Practical Bioinformatics

Probiogenomics and Probiomics

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