This book collects contributions that discuss the spread of AI, AI-GEN, and XR tools in the fields of cultural heritage and innovative design and their relationships with representation disciplines. Artificial intelligence, generative artificial intelligence, and extended reality tools, in their fruitful combination too, are today the main protagonists of the digital continuum that pervades contemporaneity. Methodologies and techniques are critically discussed, and tools and applications are originally experimented with in selected case studies. The book offers an updated panorama of international studies and provides new references aimed at improving the knowledge and technical skills of scholars, professionals, and academics.