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Giannis A: Natural Compounds Enabled
Therapies

Natural Compounds Enabled Therapies

The Renaissance in GPCR Research and Drug Discovery: Receptor Function, Receptor Structure, New Techniques, Characterization of Drug Activity, Drug Discovery is a comprehensive reference for pharmacology researchers. It focuses on utilizing novel aspects of GPCR function for therapeutic advantage and applying new chemical types to modify GPCR behavior. Recent advancements have revitalized GPCR discovery, opening unexplored avenues for new drug development. The book's content is meticulously divided into five distinct parts, covering evolutionary perspectives, novel functions, investigative technologies, therapeutic modalities, and a broad range of GPCR ligands. Beyond these key topics, the book delves into the evolution of GPCRs as drug targets, the mechanisms behind their novel functions, and the latest technologies driving research and discovery. It also highlights new and recently approved therapeutic modalities and provides a broad coverage of GPCR ligands. Edited and authored by leading researchers, this book serves as an essential reference for drug discovery researchers and medicinal chemists, as well as AI researchers exploring this drug discovery space.

Receptor Function, Receptor Structure, New Techniques, Characterization of Drug Activity, Drug Discovery

The Renaissance in GPCR Research and Drug Discovery

Dieses Fachbuch bietet eine vollständige und detaillierte Darstellung aller wichtigen Wirkstoffe und Medikamente zur intravitrealen Applikation in der Ophthalmologie. Dabei wird unter anderem auf VEGF-Inhibitoren, Corticosteroide und Antibiotika eingegangen. Eine alphabetische Auflistung – von A bis Z – macht die verschiedenen Wirkstoffe schnell auffindbar. So können Indikationen, Dosierungen oder pharmakologische Eigenschaften rasch nachgeschlagen werden. Hintergrundinformationen zu Handelsnamen, Biosimilars und Zulassungsdetails zur intravitrealen Therapie helfen zudem, den Überblick über die verfügbaren Wirkstoffe zu behalten. Im zweiten Teil des Buches strukturieren systematische Übersichtstabellen die Medikamente nach chemischer Eigenschaft und Indikation. Zudem wird eine Übersicht über die aktuell in Entwicklung befindlichen intravitrealen Medikamente gegeben.Ein Leitfaden mit tiefgehendem Wissen über intravitreale Wirkstoffe und deren Einsatz.Über den Autor:Prof. Dr. med. Antonio Bergua, FEBO, ist Oberarzt an der Augenklinik des Uniklinikums Erlangen und verantwortlich für die Uveitis-Sprechstunde sowie für den Bereich Lid-, Tränenweg- und Orbita-Chirurgie. Er hat langjährige Erfahrung in der Indikationsstellung und Anwendung intravitrealer Medikamente. Bereits 2017 veröffentlichte er das Buch „Das menschliche Auge in Zahlen“, ebenfalls beim Springer-Verlag.

Dieses Fachbuch bietet eine vollständige und detaillierte Darstellung aller wichtigen Wirkstoffe und Medikamente zur intravitrealen Applikation in der Ophthalmologie. Dabei wird unter anderem auf VEGF-Inhibitoren, Corticosteroide und Antibiotika eingegangen. Eine alphabetische Auflistung – von A bis Z – macht die verschiedenen Wirkstoffe schnell auffindbar. So können Indikationen, Dosierungen oder pharmakologische Eigenschaften rasch nachgeschlagen werden. Hintergrundinformationen zu Handelsnamen, Biosimilars und Zulassungsdetails zur intravitrealen Therapie helfen zudem, den Überblick über die verfügbaren Wirkstoffe zu behalten. Im zweiten Teil des Buches strukturieren systematische Übersichtstabellen die Medikamente nach chemischer Eigenschaft und Indikation. Zudem wird eine Übersicht über die aktuell in Entwicklung befindlichen intravitrealen Medikamente gegeben.Ein Leitfaden mit tiefgehendem Wissen über intravitreale Wirkstoffe und deren Einsatz.

Von A bis Z

Intravitreale Medikamente

Revolutionizing Neurological Disorder

Intranasal Drug Delivery Systems

An indispensable guide to the essential principles of pharmacotherapy and their application in real-world clinical practice To deliver the best possible patient-centered care, healthcare professionals must understand how to maximize the effectiveness of medications, minimize adverse reactions, and promote favorable health outcomes. Pharmacotherapy Principles and Practice, Seventh Edition provides a strong foundation of evidence-based strategies to educate learners on the process of developing, executing, monitoring, and assessing medication therapy. This comprehensive guide will help you develop a sound understanding of the fundamental principles behind pharmacotherapy for various diseases. This seventh edition reflects the latest findings in the field and includes a new chapter on health equity. The new chapter is followed by five chapters focused on special populations: pediatrics, geriatrics, palliative care, critical care, and global health and travel medicine. An additional 97 predominately disease-based chapters review epidemiology, etiology, pathophysiology, clinical presentation and diagnosis, nonpharmacologic therapy, and pharmacologic therapy, with emphasis on clear recommendations for medication selection, desired outcomes, dosing, and patient monitoring. Pharmacotherapy Principles and Practice, Seventh Edition features: - NEW Chapter: Improving Patient Care by Understanding Health Equity and the Social Determinants of Health - Structured learning objectives presented at the beginning of each chapter - Key concepts, identified by icons, highlight the disease state, patient assessment, and treatment - Patient encounters, significantly revised from the previous edition, which facilitate development of critical thinking skills - Patient Care Process section modeling the Joint Commission of Pharmacy Practitioners (JCPP) Pharmacists' Patient Care Process - Up-to-date literature citations for each chapter - Tables, figures, algorithms, and defined medical abbreviations - Self-assessment questions and answers in the Online Learning Center - Valuable table of common laboratory tests and reference ranges

Pharmacotherapy Principles and Practice, Seventh Edition

Advanced Drug Delivery Strategies

Nanoengineered Therapeutics for Lung Cancer

Targeting Intercellular Communication with Nanomedicine and Advanced Therapeutics delves into the complex world of intercellular communication biology and its implications on therapeutics. Despite significant progress in this field, there has been a lack of comprehensive understanding of the connections between different forms of communication and their role in diseases such as cancer, neurological disorders, metabolic diseases, and inflammatory/immune diseases. This book bridges this gap by providing equal insight into all areas of intercellular communication and the therapeutics in development aimed at these different forms of communication. The book is organized into fourteen chapters, covering a wide range of topics, including an introduction to the field, biological targets, challenges and approaches to overcoming biological barriers, and the significance of contact points and mechanisms of internalization. It delves into the specifics of tunneling nanotubes, extracellular vesicles, and the immune and non-immune interface in various diseases. Furthermore, it explores the crosstalk of different forms of intercellular communication and the implications of mitochondrial exchange in each of the four primary pathological areas. Targeting Intercellular Communication with Nanomedicine and Advanced Therapeutics is an essential resource for researchers, students, and professionals in the field of drug development and delivery. By connecting the dots between extracellular vesicles, tunneling nanotubes, and cell-cell junctions, this book serves as a foundation for further advancements in the science of intercellular communication and it's applications to new drug discovery and delivery. Biologists will also benefit from the way this book connects intercellular communication processes with therapeutic pathways.

Targeting Intercellular Communication with Nanomedicine and Advanced Therapeutics

Medicinal Plants in Parkinson's Therapy

Advances in Pharmacology

Brain Peptide Shuttles: Volume 105

The Untold Story of Intoxicants and the Biological Subject in Nineteenth-Century Germany

Intoxicated Ways of Knowing

The AI Frontier in Molecular Modeling and Drug Designing aims to provide a comprehensive guide on the application of AI concepts in drug designing, discovery, and molecular modeling. It delves into machine and deep learning techniques that predict structural properties of molecules, identify druggable pockets, and assess physicochemical properties of targets. The book also explores current and potential computational resources to tackle complex biological challenges. Each chapter is enriched with relevant examples, text boxes, and case studies that illustrate the practical application of AI techniques, their outcomes, and the challenges faced during implementation. This resource is tailored for researchers, students, and professionals in both academia and industry, providing them with the latest methodologies, advancements in technology, and practical insights into AI-driven drug research, structural biology, computational biology, and translational science.

The AI Frontier in Molecular Modelling and Drug Designing

A History of Medicine in Twelve Objects is an entertaining and insightful guide through the instruments that have come to shape modern medicine as we know it.

Discover the fascinating history of medicine from its primitive beginnings to the lifesaving technologies of today. Award-winning author Dr Carol Cooper takes you on a journey through the 12 objects that have come to define medicine through the ages – from the barbaric and bizarre to the inventive and impressive, this captivating read is peppered with fascinating anecdotes. In this unique history, you will discover how ill health has been with us for as long as humans have existed, as has the drive to treat and understand it. Over the course of centuries, the ways in which doctors have engaged with sickness has changed drastically, and so too have the tools at their disposal. And as these tools have morphed and evolved, our knowledge of health and disease has expanded. Medical theories have slowly advanced, allowing people to live longer and healthier lives. The 12 groundbreaking tools explored in this collection include: THE TREPHINE THE BONE SAW THE MASK THE MICROSCOPE THE STETHOSCOPE THE ETHER INHALER THE HYPODERMIC SYRINGE THE OBSTETRIC FORCEPS THE X -RAY MACHINE THE ECT MACHINE THE HIP PROSTHESIS THE HEART-LUNG MACHINE The history of these medical tools is truly astounding, revealing the true extent of human ingenuity, curiosity, and compassion. This is a book for anyone interested in medical history or looking for a fresh and dynamic take on their specialist subject. With her immense knowledge and engaging writing style, Dr Cooper delivers a history that is not for the faint of heart.

The History of Medicine in Twelve Objects

The Montreal Neurological Institute and the Origins of Neuroscience

Wired Together

Natural Compounds Enabled Therapies

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