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Pecorino Lauren: Molecular Biology of
Cancer

Molecular Biology of Cancer

Mechanisms, Targets, and Therapeutics

<ul><li>1: Introduction</li> <li>2: The transformable cancer genome: mutations versus repair</li> <li>3: Regulation of gene expression</li> <li>4: Growth factor signaling and oncogenes</li> <li>5: The cell cycle</li> <li>6: Tumour suppressor genes</li> <li>7: Apoptosis</li> <li>8: Cancer stem cells, lineage plasticity and disrupted differentiation: focus on colon cancer and leukemias</li> <li>9: Metastasis</li> <li>10: Angiogenesis</li> <li>11: Reprogrammed metabolism and diet</li> <li>12: Tumour immunology and immunotherapy</li> <li>13: Inflammation, infection, and the microbiome</li> <li>14: Cancer genomics and other methods for research and clinical development</li> </ul>

Methods in Cell Biology

Advanced Cancer Research Protocols: Volume 198

Translational Epigenetics

Lifestyle Epigenomics, a new volume in the Translational Epigenetics series, comprehensively details the interplay between lifestyle factors and epigenetic modifications associated with the onset of noncommunicable diseases and aging, shedding light on potential preventive and therapeutic strategies for disease from an epigenomics perspective. Here, more than 35 international experts in the field consider how lifestyle choices or habits can condition or prevent disease, along with tools for new research, from bioinformatics methodology to non-invasive sampling. Early, foundational chapters are followed by all-inclusive sections on epigenetic machinery in health and disease; dietary factors and epigenetics; adiposity and physical activity and epigenetics; psychological stress, social environment, toxins and contaminants exposure effects on epigenetics; and transgenerational and childhood epigenetics. To support understanding, each chapter includes a summary and key points lists, terms and definition, as well as research case studies outlining core components of recent studies, detailing their conditions, research techniques involved, and outcomes.

Lifestyle Epigenomics

Epidemiology of Infectious Disease

Methods in Enzymology

RNA Enzymology and Technology: Volume 726

Structural Biology of Amyloid Fibrils is a comprehensive reference on the structure of protein aggregates in different neurodegenerative diseases and their molecular bases. Chapters describe these structures in detail, highlighting their similarities and differences across different disease states, alongside an unprecedented overview of current developments and new hypotheses emerging in amyloid fibril structure, stability and mechanisms of formation. This volume also discusses how amyloid structure may affect the ability of fibrils to spread to different sites in a prion-like manner, as well as their role in disease. Featuring chapters on NMR, X-ray crystallography, and Cryo-EM methods, and discussing the structure of amyloid fibrils obtained directly from patients, the book allows readers to understand how polymorphism is associated with disease phenotype and how fibril structure affects and influences the cellular environment. Understanding the molecular architecture of amyloid fibrils and oligomers will be an important step towards developing therapeutic interventions based on targeting the fibrils and oligomers themselves, or the processes that generate them.

Structural Biology of Amyloid Fibrils

Practical Bioinformatics

This is an innovative book detailing the many challenges of bringing nanomedicines from the bench to the market. Through conversation, stories, descriptions, and personal accounts with leading entrepreneurs who have strived and overcome many of these barriers, readers are given a detailed outline of how nanomedicine can create future realistic solutions in medicine and health. The book takes a strong "how and why" approach.

This is an innovative book detailing the many challenges of bringing nanomedicines from the bench to the market. Through conversation, stories, descriptions, and personal accounts with leading entrepreneurs who have strived and overcome many of these barriers, readers are given a detailed outline of how nanomedicine can create future realistic solutions in medicine and health. The book takes a strong "how and why" approach.

Exploring the Potential for Nanotherapeutics

Nanomedicine

Immuno-oncology and immunotherapy Part F: Volume 201

Intelligence-Based Medicine: Subspecialty Series

Artificial Intelligence Based Primary Care: Artificial Intelligence and Human Cognition in General Practice and Family Medicine provides a comprehensive look into the integration of artificial intelligence within primary care. This book aims to bridge the gap between data scientists and primary care clinicians by presenting potential AI applications, implementation challenges, and real-world clinical scenarios in an accessible manner. Comprised of 5 sections and 20 chapters, it offers both theoretical insights and practical guidance for family medicine practitioners. Additionally, the book includes a chapter dedicated to a day in the life of a General Practitioner, showcasing the practical impact of AI. It also features an extra compendium listing the Top 100 articles and best books on Artificial Intelligence. This resource is invaluable for academics, researchers, and clinicians eager to expand their knowledge in this emerging field.

Artificial Intelligence and Human Cognition in General Practice and Family Medicine

Artificial Intelligence Based Primary Care

Matters of the Image introduces a new framework for thinking about digital images.

Matters of the Image introduces a new framework for thinking about digital images.

Designing Digital Images with Materiality, Energy, and Living Matter

Site Specific and Global Epigenomic Editing: Principles and Applications, Volume 33 highlights the expanding role that epigenetics plays in pathogenesis, the full range of sites for possible epigenetic modification, and the potential to target these sites to modulate disease progression. The book answers key questions, including which of the hundreds of epigenomic marks and features are relevant, and which are likely to serve a role in regulating gene expression, cell behavior and phenotypic outcomes. This volume is the first to provide a thorough, conceptual introduction to epigenetic regulation and a thorough accounting of sites for possible epigenetic edits and disease modulation. Included protocols and applied case studies examine early disease targets and likely pathways of therapeutic significance while also outlining common challenges in the field. The book addresses its topic in a comprehensive, but accessible manner, highlighting practical tools and burning questions remaining in the field to enable fresh research.

Principles and Applications

Site Specific and Global Epigenomic Editing: Volume 33

Foundations of Biochemistry and Biophysics

This textbook covers the physical properties of nucleic acid underlying the biological functions of DNA and RNA. It looks at the variety of nucleic acid structures observed in nature, thermodynamic and energetic principles that govern the formation and behavior of those structures, and the ways proteins recognize and manipulate nucleic acids. It

This textbook covers the physical properties of nucleic acid underlying the biological functions of DNA and RNA. It looks at the variety of nucleic acid structures observed in nature, thermodynamic and energetic principles that govern the formation and behavior of those structures, and the ways proteins recognize and manipulate nucleic acids. It

Physical Principles in Nucleic Acid Chemistry

Molecular Biology of Cancer

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