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Pecorino Lauren: Molecular Biology of
Cancer

Molecular Biology of Cancer

Mechanisms, Targets, and Therapeutics

Methods in Cell Biology

Immuno-oncology and immunotherapy Part F: Volume 201

Structural Biology of Amyloid Fibrils is a comprehensive reference on the structure of protein aggregates in different neurodegenerative diseases and their molecular bases. Chapters describe these structures in detail, highlighting their similarities and differences across different disease states, alongside an unprecedented overview of current developments and new hypotheses emerging in amyloid fibril structure, stability and mechanisms of formation. This volume also discusses how amyloid structure may affect the ability of fibrils to spread to different sites in a prion-like manner, as well as their role in disease. Featuring chapters on NMR, X-ray crystallography, and Cryo-EM methods, and discussing the structure of amyloid fibrils obtained directly from patients, the book allows readers to understand how polymorphism is associated with disease phenotype and how fibril structure affects and influences the cellular environment. Understanding the molecular architecture of amyloid fibrils and oligomers will be an important step towards developing therapeutic interventions based on targeting the fibrils and oligomers themselves, or the processes that generate them.

Structural Biology of Amyloid Fibrils

Epidemiology of Infectious Disease

Foundations and Frontiers in Enzymology

Sustainable Process Intensification for Biocatalysis: Applications in Enzymology and Biotechnology, a new volume in the Foundations and Frontiers of Enzymology series, offers applied instruction in process intensification principles for applications in enzymology and biotechnology, helping researchers and practitioners implement these techniques across various uses and industries, from healthcare to food and biofuel. Leaders in the field discuss a full range of approaches and enabling technologies, from microwave to ultrasound, hydrodynamic cavitation, and combination chemical and biological catalysis techniques, such as multiphase reactors, microreactors, scale-bioprocesses, and enzyme cascades. Later chapters examine ongoing advances and their implementation across different industries, including pharmaceuticals, perfumes, polymers, and agrochemicals, with a final chapter discussing next steps in research and future directions. Throughout the book, and across applied examples, emphasis is placed on driving sustainable research approaches and manufacturing.

Applications in Enzymology and Biotechnology

Sustainable Process Intensification for Biocatalysis

Current Topics in Developmental Biology

Cell Shape and Position during Development: Volume 166

Industrial and Environmental Microbiology

Genomic and Precision Medicine in Clinical Practice

Medical and Health Genomics of South Asia, a new volume in the Genomic and Precision Medicine in Clinical Practice series, offers a thorough discussion of medical genomics as applied across South Asian nations, from India to Pakistan, Bangladesh, Sri Lanka, and Nepal, as well as in South Asian populations abroad. Here, global chapter authors consider genomic variation and the population heterogeneity of genetic, infectious, and lifestyle diseases in South Asia, along with successful modes of population health management for these inherited disorders and other applications of clinical genomics for improved individual health in the region. Adopting an applied approach, this book first reviews basic genomic models and population study formats, as well as the anthropological and genetic history of South Asia. The following sections examine genomic epidemiology and population health in the South Asian context; examples of genomic medicine's use in combating major health challenges in the region; genomic healthcare infrastructure; and related social, ethical, legal, and economic aspects central to impactful genomic medicine.

Medical and Health Genomics of South Asia

Foundations of Biochemistry and Biophysics

This textbook covers the physical properties of nucleic acid underlying the biological functions of DNA and RNA. It looks at the variety of nucleic acid structures observed in nature, thermodynamic and energetic principles that govern the formation and behavior of those structures, and the ways proteins recognize and manipulate nucleic acids. It

This textbook covers the physical properties of nucleic acid underlying the biological functions of DNA and RNA. It looks at the variety of nucleic acid structures observed in nature, thermodynamic and energetic principles that govern the formation and behavior of those structures, and the ways proteins recognize and manipulate nucleic acids. It

Physical Principles in Nucleic Acid Chemistry

Translational Epigenetics

Lifestyle Epigenomics, a new volume in the Translational Epigenetics series, comprehensively details the interplay between lifestyle factors and epigenetic modifications associated with the onset of noncommunicable diseases and aging, shedding light on potential preventive and therapeutic strategies for disease from an epigenomics perspective. Here, more than 35 international experts in the field consider how lifestyle choices or habits can condition or prevent disease, along with tools for new research, from bioinformatics methodology to non-invasive sampling. Early, foundational chapters are followed by all-inclusive sections on epigenetic machinery in health and disease; dietary factors and epigenetics; adiposity and physical activity and epigenetics; psychological stress, social environment, toxins and contaminants exposure effects on epigenetics; and transgenerational and childhood epigenetics. To support understanding, each chapter includes a summary and key points lists, terms and definition, as well as research case studies outlining core components of recent studies, detailing their conditions, research techniques involved, and outcomes.

Lifestyle Epigenomics

Practical Bioinformatics

The Future of Human Evolution

Progress in Biochemistry and Biotechnology

Methods for Synthesis of Peptide, Oligonucleotide and Oligosaccharide Libraries and Applications

Combinatorial Biotechnology

Molecular Biology of Cancer

Bibliografische Angaben

Schlagworte

Bibliografische Angaben

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