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Pecorino Lauren: Molecular Biology of
Cancer

Molecular Biology of Cancer

Mechanisms, Targets, and Therapeutics

<ul><li>1: Introduction</li> <li>2: The transformable cancer genome: mutations versus repair</li> <li>3: Regulation of gene expression</li> <li>4: Growth factor signaling and oncogenes</li> <li>5: The cell cycle</li> <li>6: Tumour suppressor genes</li> <li>7: Apoptosis</li> <li>8: Cancer stem cells, lineage plasticity and disrupted differentiation: focus on colon cancer and leukemias</li> <li>9: Metastasis</li> <li>10: Angiogenesis</li> <li>11: Reprogrammed metabolism and diet</li> <li>12: Tumour immunology and immunotherapy</li> <li>13: Inflammation, infection, and the microbiome</li> <li>14: Cancer genomics and other methods for research and clinical development</li> </ul>

Recent Trends in Enzyme Immobilization

Methods in Cell Biology

Immuno-oncology and immunotherapy Part F: Volume 201

Immuno-oncology and Immunotherapy Part G: Volume 202

This is an innovative book detailing the many challenges of bringing nanomedicines from the bench to the market. Through conversation, stories, descriptions, and personal accounts with leading entrepreneurs who have strived and overcome many of these barriers, readers are given a detailed outline of how nanomedicine can create future realistic solutions in medicine and health. The book takes a strong "how and why" approach.

Exploring the Potential for Nanotherapeutics

Nanomedicine

Foundations of Biochemistry and Biophysics

This textbook covers the physical properties of nucleic acid underlying the biological functions of DNA and RNA. It looks at the variety of nucleic acid structures observed in nature, thermodynamic and energetic principles that govern the formation and behavior of those structures, and the ways proteins recognize and manipulate nucleic acids. It

Physical Principles in Nucleic Acid Chemistry

Matters of the Image introduces a new framework for thinking about digital images.

Designing Digital Images with Materiality, Energy, and Living Matter

Translational Epigenetics

Chromatin Signaling and Diseases, Second Edition, a volume in the Translational Epigenetics series, covers the molecular mechanisms that regulate gene expression, which governs embryonic development, growth, and human pathologies associated with aging, such as cancer. Although human genome sequencing continues to improve, molecular mechanisms regulating gene expression remain largely misunderstood. The impact of gene expression defects associated with malfunctioning chromatin signaling are considered in this update. In addition, this new edition has addresses developments in the field, from phase separation of membrane-less organelles and local segregation of factors to chromatinization of naked foreign DNA and cancer evolution as regulated by chromatin signaling. Chromatin signaling proposes that small protein domains recognize chemical modifications on the genome scaffolding histone proteins, facilitating the nucleation of enzymatic complexes at specific loci that then open up or shut down the access to genetic information, thereby regulating gene expression. The addition and removal of chemical modifications on histones, as well as the proteins that specifically recognize these are also considered.

Molecular Biology of Cancer

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