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Rabkin E: Torn

Torn

Fashion and Postmodernism

Topical Dermal Drug Delivery: Concepts and Advances compiles, in a single volume, the most recent advances in topical and dermal formulations for the treatment of skin disorders. The book covers three major concepts. The skin anatomy and physiology part includes chapters focused on relevant information for drug delivery. The second part of the book deals with several recent topical dermal drug delivery systems, including computational methods, permeation enhancers, bio precursors, hydrogels, emugels, exosomes and several nanotechnology enabled systems. The third and final part covers scaling up, toxicity, clinical trials, and regulatory considerations. This is a complete reference for academic and corporate pharma researchers investigating targeted drug delivery to the skin. Medical &amp; Health Sciences researchers would also benefit from understanding the delivery systems covered in this book.

Concepts and Advances

Topical Dermal Drug Delivery

Drugs and the Pharmaceutical Sciences

This book provides insight into the world of pharmaceutical quality systems and the key elements that must be in place to change the business and organizational dynamics from task-oriented procedure-based cultures to truly integrated quality business systems that are self-detecting and correcting. Chapter flow has been changed to adopt a quality systems organization approach, and supporting chapters have been updated based on current hot topics including the impact of the worldwide supply chain complexity and current regulatory trends.Key Features<ul> <li>Presents insight into the world of pharmaceutical quality systems.</li> <li>Analyzes regulatory trends and expectations.</li> <li>Includes approaches and practices used in the industry to comply with regulatory requirements.</li> <li>Discusses recent worldwide supply chain issues.</li> <li>Delivers valuable information to a worldwide audience regarding the current Good Manufacturing Practices in the industry.</li> </ul>

Good Manufacturing Practices for Pharmaceuticals

This book presents a cohesive collection of cutting-edge research focused on advanced decision-support methodologies for complex and ambiguous operational contexts. This volume systematically assembles ten pivotal studies employing uncertain decision-making, multi-criteria decision analysis (MCDA), and tailored optimization models to address substantive challenges in supply chain management, sustainable operations, and strategic planning.The contributions span a rigorous methodological spectrum, including fuzzy PDCA cycles for green performance evaluation, hybrid MCDM frameworks for lean tool selection, and robust optimization for resilient network design. Applications are drawn from critical domains such as healthcare logistics during epidemic response, sustainable supply chain configuration, and large-scale project trade-off analysis under resource constraints. Each chapter demonstrates the translation of theoretical computational models into applied solutions for decision-making under volatility, incomplete information, and multi-objective pressures.This volume will serve as a significant reference for academics and graduate researchers in management science, operations research, and industrial engineering. It provides a structured examination of how contemporary soft computing and operational research techniques can be leveraged to enhance analytical rigor and strategic outcomes in the face of pervasive environmental uncertainty.The chapters in this book were published in International Journal of Management Science and Engineering Management.

Innovation Decision-Making Under Uncertain Environment

Anthocyanins esterified with one or more acid groups are known as acylated anthocyanins, which exhibit higher stability and antioxidant activity compared to nonacylated ones and are of interest to the food and beverage industry. It is known that the structural differences among anthocyanins will influence their specific roles and effectiveness in the different applications in which they may be used. This book compiles and summarizes data regarding knowledge on acylated anthocyanins, ranging from their physical and chemical particularities to their health effects, including bioaccessibility, bioavailability, and bioactivity, as well as their different technological applications.Key Features:<ul> <li>Provides information on the different areas where acylated anthocyanins are being utilized</li> <li>Discusses the characteristics of acylated anthocyanins and the effect of their structural features on different properties</li> <li>Includes a database of acylated anthocyanins from both nonedible and edible sources</li> </ul>

Chemistry, Bioavailability, Bioactivity, and Applications

Acylated Anthocyanins

Membrane Transporters and Drug Delivery: A Comprehensive and Multidisciplinary Guide is a comprehensive reference on the rapidly evolving field of membrane transporters and their role in drug delivery. The book begins with a comprehensive introduction to membrane transporters and their function, structure, and regulation mechanisms. It then moves into the impact of diseases on transporters and how this may affect pharmacokinetics. The book also presents the latest advancements in transporter-mediated drug delivery, examines the roles of both efflux and influx transporters in drug pharmacokinetics, and covers different strategies for utilizing membrane transporters for drug delivery and targeting specific tissues and cell types. It concludes with a discussion on the regulatory and industrial aspects of transporter-related projects, explores the potential of artificial intelligence in transporter and drug delivery research, and offers a glimpse into future challenges and perspectives in this field.

A Comprehensive and Multidisciplinary Guide

Membrane Transporters and Drug Delivery

Routledge Revivals

First published in 1987, International Capitalism and Industrial Restructuring counters the idea that industrial restructuring is a relatively problem-free stage in the evolution to a post-industrial society.

A Critical Analysis

International Capitalism and Industrial Restructuring

“Almost Reckless is not just a book, it's a permission slip. It's about the courage it takes to step off the algorithm's path, the clarity that comes from defining your own principles, and the joy of building something that feels unmistakably yours.” —Will Guidara, bestselling author of Unreasonable Hospitality Amy Smilovic's cult fashion brand, Tibi, was a thriving $70 million business when she realized she was working toward someone else's idea of success. So she threw out the rulebook of how things should be done and went with her gut instead. Today Tibi is more successful than ever, and all on Smilovic's groundbreaking entrepreneurial terms.&nbsp; In Almost Reckless, she invites you to get comfortable with embracing smart risks in pursuit of your own vision. Sharing her story and drawing on her years of helping others identify their values and principles, Smilovic teaches you to hone your gut, and your trust in it. With humor and practicality she coaches you in how to determine what success means to you, including: <ul><li>why you don’t have to listen to the data guys</li><li>why you should be a Creative Pragmatist</li><li>why sticking to your principles isn’t incompatible with success</li><li>why work/life balance is bullshit</li></ul> Almost Reckless is the essential blueprint for entrepreneurs, leaders, creatives, and anyone who wants a working life that feels aligned with who they truly are.

A Creative and Pragmatic Approach to Taking Risks

Almost Reckless

The Industrial Revolution (1958) examines the various interpretations of early industrialization in Britain. It assesses and synthesises the many writings on the industrial revolution to produce an insightful essay that spans the theories and thinking on the subject.

An Introductory Essay

The Industrial Revolution 1750–1850

Interface Science and Technology

Phoretic Motions of Liquid Droplets: A Theoretical Analysis provides a detailed description of the fundamentals of the electrostatics and electrokinetics of various kinds of droplets: dielectric droplets, conducting droplets such as liquid metal droplets, polymeric liquid droplets and the implications they have for their broad practical applications. It is crucial to fully understand the underlying electrokinetic mechanisms before any meaningful practical applications of liquid droplets can be launched successfully. This is the first book to directly address phoretic motion of droplets; previously there has only been brief mention in texts mostly about solid particles, on which there is much more literature. Droplets of different kinds have different applications in practice. For instance, conducting droplets like liquid metal droplets have an inherent advantage in drug delivery over liposomes of dielectric droplets in terms of chemiphoresis, although both are widely used in drug delivery and micro/nanofluidic operations, among other practical applications. The book provides insights and guidelines for design engineers in drug delivery even in the fabrication stage of the droplets carrying therapeutic chemicals. Moreover, it is helpful in analyzing data for experimental researchers as well. For instance, a droplet filled with dielectric materials may not behave electrokinetically like a dielectric droplet under certain circumstances in practice, as might be expected by experimentalists. Phoretic Motions of Liquid Droplets is written for researchers, industry engineers, and graduate and postdoc students in the field of colloidal and interface science and technology who are working on colloidal physics aspects and focused on electrokinetics, primarily from a chemical engineering, biomedical and biochemical engineering background.

A Theoretical Analysis

Phoretic Motions of Liquid Droplets

Routledge Studies in Luxury Management

This book critically analyses and documents a shift of ethical consumption patterns through Western yoga commodities, services and transformational experiences that affect women within consumer culture. Western yoga uses fashion and luxury branding strategies to promote commodities that support an individualised, exclusive, and privatised quest for meaning, ritual, belonging and community. These new status signifiers demonstrate how Western yoga has become an essential contemporary sign and symbol of the aspirational class. This book thus discusses how aspirational Western yoga brands, yoga studios, and social media influencers commodify wellness by distributing cultural capital as postfeminist spiritual capital through the promotion of exclusive and consciously-minded aesthetic and ethical transformational experiences within the wellness industry.Through the contemporary case studies presented in this book, the reader will be exposed to the complex tactics that yoga brands, yoga studios and 'yogalebrities' use to generate aspirational conscious luxury commodities that promise entangled physical and spiritual distinction. This book reveals how yoga practitioners are encouraged to arrive at self-optimisation and self-empowerment not after the trials and tribulations of the human experience but after a highly controlled and exclusive experiential economic transaction that anchors the ego to bodily labour and elitist luxury fashion design ideals. These case studies will expose the reader to how these new consumption patterns converge, stylising and commodifying the psychic life of women.This book will appeal to an academic audience with an interest in fashion and luxury studies, luxury management, consumer culture, gender studies and critical spiritual practices.

Conscious Luxury, Western Yoga and Fashion

The Commodification of Wellness

This book simplifies the process regarding the application of usability to medical devices for new developers by providing a thought-out walkthrough of what is involved and how the expectations from the essential standards affect their work and why. Based on the authors' experiences, the information in the book provides other more seasoned experts with a wealth of insight and nuggets of new perspectives on addressing the usability of medical devices, particularly medical software.The discussion in the book is rooted in recent real-world experiences from both the manufacturer and assessment body sides-the authors provide a novel high-level "roadmap" to using usability engineering to guide development activities from initial conceptual design to research, development, and ultimately release of a medical device. They build toward this map throughout the book and ultimately present the full model. This roadmap is the result of the authors' experiences of taking a research project and launching both a medical device and a medical device business after obtaining all the necessary regulatory approvals.The book helps product developers to understand the usability requirements around their own work, and to also better understand their users and to present the expected usability information in a way that is readily understood by the auditors. Managers of such work will also greatly benefit from the discussion of the required deliverables and the goals of the usability activities. Finally, the authors ease the divide between manufacturers and healthcare professionals using medical devices. By simultaneously showing the requirements for the manufacturer's development process and also discussing the realities of work on the healthcare side, the authors facilitate collaboration.

Human Factors for Medical Device Development

Medical-Device Usability

Innovative Nanocarriers for Stimulated Drug Delivery: A Comprehensive Guide to Stimuli-responsive Nanoparticles summarizes recent advances and achievements in nanocarriers responsive to external or internal stimuli. The book presents different stimuli-sensitive strategies and their applications in drug delivery, therapy, and theranostics. Sections provide fundamental knowledge on the experiential and experimental aspects of stimuli-responsive nanocarriers, discuss external-responsive nanocarriers for biomedical applications, such as ultrasound, thermal, magnetic, light, and electric field-response systems, and describe internal stimuli-responsive nanocarriers for biomedical applications, including pH, hypoxia, redox potential, enzyme, glucose, and microRNA-responsive nanocarriers. Additionally, the book covers dual and multimodal-responsive nanocarriers and the therapeutic aspects of stimuli-responsive nanocarriers, such as metallic and non-metallic stimuli-responsive nanocarriers in the treatment of various cancer and noncancerous diseases. Finally, recent advances and regulatory aspects of stimuli-responsive nanocarriers, including clinical translation, challenges, biological toxicity, safety issues, clinical trials, and future perspectives are covered.

A Comprehensive Guide to Stimuli-responsive Nanoparticles

Innovative Nanocarriers for Stimulated Drug Delivery

Torn

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