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Catalogue complet

How Big Pharma failed to end a pandemic, and what it tells us about the global economy

Dearden N: Pharmanomics

Pharmanomics

How Big Pharma Destroys Global Health

Introduction: Bad Apples 1. A History of Scandal 2. A Hedge Fund with a Pharmaceutical Firm Attached 3. It Was Greed, My Friends 4. The Pandemic Begins 5. Recolonising the Global Economy 6. The Hospital That Became a Trading Floor 7. A New Hope 8. Reach for the Moon

Innovative Nanocarriers for Stimulated Drug Delivery: A Comprehensive Guide to Stimuli-responsive Nanoparticles summarizes recent advances and achievements in nanocarriers responsive to external or internal stimuli. The book presents different stimuli-sensitive strategies and their applications in drug delivery, therapy, and theranostics. Sections provide fundamental knowledge on the experiential and experimental aspects of stimuli-responsive nanocarriers, discuss external-responsive nanocarriers for biomedical applications, such as ultrasound, thermal, magnetic, light, and electric field-response systems, and describe internal stimuli-responsive nanocarriers for biomedical applications, including pH, hypoxia, redox potential, enzyme, glucose, and microRNA-responsive nanocarriers. Additionally, the book covers dual and multimodal-responsive nanocarriers and the therapeutic aspects of stimuli-responsive nanocarriers, such as metallic and non-metallic stimuli-responsive nanocarriers in the treatment of various cancer and noncancerous diseases. Finally, recent advances and regulatory aspects of stimuli-responsive nanocarriers, including clinical translation, challenges, biological toxicity, safety issues, clinical trials, and future perspectives are covered.

A Comprehensive Guide to Stimuli-responsive Nanoparticles

Innovative Nanocarriers for Stimulated Drug Delivery

Membrane Transporters and Drug Delivery: A Comprehensive and Multidisciplinary Guide is a comprehensive reference on the rapidly evolving field of membrane transporters and their role in drug delivery. The book begins with a comprehensive introduction to membrane transporters and their function, structure, and regulation mechanisms. It then moves into the impact of diseases on transporters and how this may affect pharmacokinetics. The book also presents the latest advancements in transporter-mediated drug delivery, examines the roles of both efflux and influx transporters in drug pharmacokinetics, and covers different strategies for utilizing membrane transporters for drug delivery and targeting specific tissues and cell types. It concludes with a discussion on the regulatory and industrial aspects of transporter-related projects, explores the potential of artificial intelligence in transporter and drug delivery research, and offers a glimpse into future challenges and perspectives in this field.

A Comprehensive and Multidisciplinary Guide

Membrane Transporters and Drug Delivery

A Sunday Times Book of the Year 'A welcome antidote to the dangerous cult of overdiagnosis and the commodification of normal distress' PHILIPPA PERRY How can we reconsider the way in which we think about, treat and care for those in distress? More and more people are being diagnosed with ADHD and autism. More and more people are being diagnosed with mental disorders. Young people are being medicalised for behaviours that might be explained as entirely normal in other parts of the world. Distress has been commodified over many decades by pharmaceutical companies, the media and the psychiatric establishment. So how can we know when distress is normal and when it is something that needs to be treated? In Searching for Normal, Sami Timimi explores the political and cultural context of these phenomena and presents a deeply humane approach that looks at the person as a whole - their family context, their culture, their personal resilience - and advocates for a reframing of how we think about and treat distress.

A New Approach to Understanding Mental Health, Distress and Neurodiversity

Searching for Normal

Routledge Studies in Health in Africa

Over the past 30 years, an ever-expanding community of global health actors have been intervening in the poorest parts of the world with the aim of combatting disease and improving health outcomes. While many global health programmes in the Global South have been successful in saving lives, their successes have often been compromised by poor coordination, inefficiency and a lack of alignment with national priorities.This book outlines the deep historical and political dimensions of this fragmentation, using rural Zambia as a case study. In the name of global health, different actors produce and circulate radically different stories about how to improve health. These narratives not only contribute to a fragmented landscape of health provision but also create more subtle and pervasive forms of fragmentation in the everyday lives of health workers, patients and government officials. Based on long-term ethnographic fieldwork in rural Zambia, this book examines three different global health interventions driven by differing stories of salvation, community and experimentation. Tracing the longer history of these stories, the book shows how they have failed to account for the realities of life in rural Zambia.Providing an innovative and nuanced analysis of global health that challenges the idea of fragmentation as simply a technical problem, this book will be an important read for researchers of global health and African studies.

Saviourism, Community, and Experimentation in Zambia

Global Health in Fragments

This ethnography of an English adult male prison explores a polycrisis of violence, self-harm, overcrowding, and the COVID-19 pandemic. Using Bourdieu's field theory, it uniquely highlights the complex interplay of policy, people, and practices to reveal how prisons exacerbate social inequality. The book uncovers paradoxes between prison's stated aims of safety, security, and (re)habilitation and their adverse realities, including the harms to prisoners' reintegration upon release. The prison operates as "a perfect storm" of mutually reinforcing conditions that reproduce harmful outcomes. The book contends that the real crisis isn't that prisons fail, it's that we continue to believe they're meant to succeed.

An Ethnography of a Prison Crisis

'A Perfect Storm'

Lipid Nanoparticles-Based mRNA Delivery System offers a comprehensive exploration of lipid nanoparticles (LNPs), the most promising delivery vehicles for mRNA. The book consolidates current knowledge, identifies research gaps, and provides insights into the latest developments in LNP technologies, making it an essential resource for researchers, pharmaceutical developers, and clinicians at the forefront of mRNA therapeutics. Exploring the intricacies of LNP formulation, the book covers a wide range of topics, including the fundamental principles of lipid nanoparticles, design strategies for effective mRNA encapsulation, and the unique challenges associated with various routes of administration-such as intravenous, oral, transdermal, and intranasal delivery. The book also examines the therapeutic applications of lipid-based systems, particularly in vaccines and cancer immunotherapy, while addressing critical challenges like immunogenicity and regulatory considerations. Final sections provide a forward-looking perspective on future trends and innovations in lipid-based mRNA delivery systems, ensuring that readers are well-equipped to navigate this rapidly evolving field.

Lipid Nanoparticles-Based mRNA Delivery System

Concepts for Critical Psychology

This book examines how neoliberal power shapes individual subjectivity in contemporary American workplaces through the lens of the Great Resignation-the 2021 mass voluntary job departure phenomenon.Drawing on in-depth interviews and a Foucauldian framework, the book traces how neoliberal rationalities of choice, flexibility, and self-optimization shape the ways individuals explain their labor decisions and evaluate their lives. Rather than treating the Great Resignation as a singular rupture, the analysis situates it within longer historical transformations in governance, capitalism, and employment relations.The book identifies differentiated modes of labor subjectivity-alignment, negotiation, and refusal-showing how workers variously inhabit, strain against, or attempt to revalue dominant norms of work and responsibility. Across chapters, it demonstrates how quitting becomes intelligible not simply as resistance or market behavior, but as an ethical and discursive practice shaped by uneven opportunities, affective demands, and institutional constraints. In doing so, the book reveals both the durability and the limits of neoliberal labor governance.Offering a theoretically rich account of how labor and life might be reimagined, the book is intended for scholars and advanced students in sociology, critical psychology, labor studies, and social theory, as well as readers interested in work, governance, and contemporary capitalism. It will also appeal to researchers and practitioners seeking critical insight into current debates about labor, precarity, and organizational life.

A Foucauldian Analysis

The Great Resignation as Neoliberal Compliance and Critique

Drugs and the Pharmaceutical Sciences

Pharmaceutical Process Engineering

The inside story of the race to develop Ozempic - the world's first truly effective and safe obesity drug - and its potentially revolutionary effects on public health, and our deeper culture and values.'A FASCINATING DEEP DIVE' Guardian'VERY ENGAGING' New Scientist'ENLIGHTENING' Publishers WeeklyA 'cure' for obesity has long evaded the pharmaceutical industry, until the development of Ozempic: a diabetes medication that targets the GLP-1 hormone and makes people feel fuller for longer.After decades of research, Ozempic's creator Novo Nordisk quickly became one of the most valuable companies in Europe. Now it struggles to keep up with its rivals in an explosive and lucrative market for weight-loss injections. The treatment is so effective that it's already disrupted industries from healthcare to fast food to fashion. Financial investment has skyrocketed and public demand continues to soar alongside celebrity endorsements. Beyond million-dollar profits, countless lives could now be saved from preventable diseases, but one question remains: are these drugs too good to be true?Through original reporting and rigorous research, Aimee Donnellan uncovers the complicated history of a medical breakthrough that is changing the world, while raising difficult questions about inequality, morality, our beauty ideals and the pursuit of thinness. Along the way, Donnellan profiles the female scientist whose contributions to the discovery of GLP-1 were overlooked and some of the earliest Ozempic users share powerful testimonies.Off the Scales is a revelatory, gripping and urgent study of the unexpected consequences of finally getting what we've wanted for so long.'A lively tale of the stunning rise of Ozempic. This detailed, eye-opening account is bolstered by an insider look at commercial drug development' Irish Times'The definitive account of a singular global force - essential reading to help us understand what has been unleashed and what may be coming next' Andy Slavitt, author of Preventable'[A] Meticulously reported account ... and it is done very well - briskly and brightly ... Donnellan has performed a public service by taking down the first draft of history: by speaking to the main players and untangling the rivalries and disputes' The Times'A riveting read ... Donnellan captures the drama behind the science ... and explores the wider implications for society, health and business in this deeply researched book' John Collingridge, Guardian business editor

The Inside Story of Ozempic and the Race to Cure Obesity

Off the Scales

Leadership in Global Health outlines the essential leadership principles that transform promising health interventions into global movements, offering a timely and compelling blueprint for leaders seeking to drive lasting, scalable change.Grounded in decades of lessons from global health successes and failures, and illustrated through deeply analyzed, real-world case studies, the book reveals what happens when leadership meets coordinated action. These stories - from the eradication of smallpox and the large-scale delivery of malaria bed nets to the community-based innovations of Ethiopia's Health Extension Program and the lightning-fast COVID-19 vaccine rollout - show how leadership in global health is not one-size-fits-all, but rather dynamic, responsive, and deeply human. In an era where complex health challenges range from emerging pandemics to enduring inequities, the book centers the role of leadership-strategic, adaptive, and collaborative-as the critical engine for scaling health interventions, offering readers not only compelling narratives from the field, but also practical tools and reflections which give the book a forward-looking focus.Building to offer a roadmap for developing the next generation of global health leaders equipped to thrive in multi-sectoral, rapidly evolving environments, it will be essential reading for students, scholars and practitioners across Global Health, Public Health, Leadership and Development Studies.

A Strategic Blueprint for Scalable Change

Leadership in Global Health

Pelican Books

'One of the clearest and most important studies to be published on education, worldwide, in many decades' Danny Dorling Does the education system make better people? Why are so many - teachers and students alike - stressed and dissatisfied? Do we need to revive real education? Ideally, education is about the pursuit of truth, beauty and morality. But in the last few decades, a perilous fixation with human capital - skills, knowledge and aptitudes required for the labour market - has trampled over curricula, schools and universities. Rather than learning how to think critically about the world, from cradle to grave students are trained to be more effective workers, to make more money, and to serve an hegemonic ideology. Teachers and researchers are pressed to serve those goals. In this concluding book in his series on the commons, Guy Standing shows us how education - intrinsically a common public good - has been enclosed, privatised, financialised and corrupted, turned into an instrument of societal control, not human emancipation, weakening democracy, not strengthening it. Human Capital charts how the education industry largely serves commercial interests, not its teachers and students, and considers how to revive its lost values, to save society for the common good.

The Tragedy of the Education Commons

Human Capital

The Urban Book Series

Disrupting traditional notions of urban and city planning, this volume examines the intricate interplay of conflicts, the emergence of new borders for refugees and migrants, colonial legacies and postcolonial policies, and grassroots struggles for better social policies. As the second volume complementing 
 Border Urbanism: Transdisciplinary Perspectives
 (2023), 
 Urbanism at Borders: Navigating New Frontiers in a Globalized World
 presents a comprehensive exploration of the evolving urban fabric, highlighting 32 of the most compelling, under-explored themes presented at the second Urbanism at Borders Global conference, convened in 2019 in Malaga, Spain. These chapters scrutinize various aspects of border trends to better understand how spatial justice, urban form and the lives of marginalized and common citizens are affected by borders.
 Authors in this volume examine the perception, interpretation, and nature of borders, shedding light on their transformative influence on historical, cultural, and socioeconomic interests. The book focuses on how urban border conditions determine the mobility of goods, resources, and populations, defining interactions and relationships that extend from geopolitical relations to the intricacies of everyday life. Temporal issues arising from diverse urban conditions are addressed, with each chapter contributing to a critical discourse on border urbanism and the nuanced interplay between conflict and coexistence resulting from the delineation, separation, and segregation imposed by borders. This volume goes beyond conventional discourses on borders, exploring often overlooked or hereto-thought unrelated dimensions such as tourism and housing. By broadening the narrative to encompass these critical aspects, this volume enhances understandings of and proposes solutions to contemporary challenges, recognizing that borders–and their effects–manifest at different scales and in different ways.

Navigating New Frontiers in a Globalized World

Urbanism at Borders

Pharmanomics

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