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Interdisciplinary Cancer Research

Cancers in Different Conditions, Cancer
Research Methods and Diagnosis: An Inter

Cancers in Different Conditions, Cancer Research Methods and Diagnosis: An Interdisciplinary Approach

Challenges in Solid Tumors and Other Cancers: An Interdisciplinary Approach

Artificial Intelligence and Bioinformatics in Cancer: An Interdisciplinary Approach

Cancer Metastasis, Management and Complications: An Interdisciplinary Approach

Gynecological Cancers: An Interdisciplinary Approach

The “Urogenital Cancers: An Interdisciplinary Approach” is the sixteenth volume of the “Interdisciplinary Cancer Research” series, publishes comprehensive volume on diagnosis and treatment of urogenital cancers. The volume starts with a general chapter on interdisciplinary approach in genitourinary cancers. After discussion on upper tract urothelial carcinoma, bladder cancer, and renal cell carcinoma, immunobiology of testicular cancer is explained. The subsequent chapters are focused on prostate cancer. This is the main concept of Cancer Immunology Project (CIP), which is a part of Universal Scientific Education and Research Network (USERN). This interdisciplinary book will be of special value for urologists, nephrologists, and oncologists who wish to have an update on diagnosis and treatment of urogenital cancers.

Urogenital Cancers: An Interdisciplinary Approach

The “Cutaneous Cancers: An Interdisciplinary Approach” is the fifteenth volume of the “Interdisciplinary Cancer Research” series, publishes comprehensive volume on diagnosis and treatment of cutaneous cancers. The volume starts with a general chapter on interdisciplinary approach in cutaneous cancers. Epigenomic markers in dermato-oncology is discussed in the next chapter. Macrophage-mediated cancer immunology and the role of inflammatory cells in skin cancer genesis are explained in subsequent chapters. Pathophysiology and treatment of specific cutaneous cancers, including melanoma, are discussed in the following chapters. This is the main concept of Cancer Immunology Project (CIP), which is a part of Universal Scientific Education and Research Network (USERN). This interdisciplinary book will be of special value for dermatologists and oncologists who wish to have an update on diagnosis and treatment of cutaneous cancers.

Cutaneous Cancers: An Interdisciplinary Approach

The “Brain Tumors: An Interdisciplinary Approach” is the thirteenth volume of the “Interdisciplinary Cancer Research” series, publishes comprehensive volume on diagnosis and treatment of brain tumors. It starts with a general title on an interdisciplinary approach in brain tumors. Inherited genetics syndromes associated with central nervous system tumors as well as the impact of epigenetic methylation on gliomagenesis were explained. Then new approaches on precision medicine in brain tumors are discussed. After discussion on neurosurgical management of brain tumors, neuroimaging and radiosurgery of brain tumors are explained. Novel approaches to bypassing the blood-brain barrier for drug delivery to brain tumors are also discussed. After presentation of pediatric low-grade gliomas, treatment of glioblastoma is the subject of other chapters. The potential role of artificial intelligence in the treatment of glioblastoma is discussed in the last chapter. This is the main concept of Cancer Immunology Project (CIP), which is a part of Universal Scientific Education and Research Network (USERN). This interdisciplinary book will be of special value for neurosurgeons and oncologists who wish to extend their knowledge on brain tumors.

Brain Tumors: An Interdisciplinary Approach

The “Neuroendocrine and Oral Cancers: An Interdisciplinary Approach” is the fourteenth volume of the “Interdisciplinary Cancer Research” series, publishes comprehensive volume on diagnosis and treatment of neuroendocrine tumors and oral cancers. The volume starts with a chapter on signaling pathways in neurological cancers and a general chapter on neuroendocrine neoplasms. Thyroid cancer and adrenal gland carcinoma as two examples of endocrine tumors are explained in this volume. The other chapters focus on oral cancers, where biomarkers for diagnosis and therapeutic opportunities are discussed. The last chapter also explains the challenges on oral and dental care on oncology. This is the main concept of Cancer Immunology Project (CIP), which is a part of Universal Scientific Education and Research Network (USERN). This interdisciplinary book will be of special value for neurologists, endocrinologists, dentists, oncologists who wish to have an update on diagnosis and treatment of endocrine tumors and oral cancers.

Neuroendocrine and Oral Cancers: An Interdisciplinary Approach

Hepatobiliary cancers, including hepatocellular&nbsp;carcinoma&nbsp;and&nbsp;biliary&nbsp;tract&nbsp;cancers, have high rate of mortality and low survival rate. The third volume of the “Interdisciplinary Cancer Research” series, entitled “Hepatobiliary Cancers: An Interdisciplinary Approach” publishes comprehensive volumes on mechanisms of hepatobiliary cancers and therapeutic modalities and presents the most updated and peer-reviewed chapters on hepatobiliary cancers. This interdisciplinary series is of special value to researchers working on cell biology, immunology, biochemistry, genetics, and practitioners working on oncology and gastroenterology. This is the main concept of Cancer Immunology Project (CIP), which is a part of Universal Scientific Education and Research Network (USERN). This interdisciplinary book will be of special value for researchers, oncologists, and gastroenterologists who wish to extend their knowledge on hepatobiliary cancers.

Hepatobiliary cancers, including hepatocellular&nbsp;carcinoma&nbsp;and&nbsp;biliary&nbsp;tract&nbsp;cancers, have high rate of mortality and low survival rate. The third volume of the “Interdisciplinary Cancer Research” series, entitled “Hepatobiliary Cancers: An Interdisciplinary Approach” publishes comprehensive volumes on mechanisms of hepatobiliary cancers and therapeutic modalities and presents the most updated and peer-reviewed chapters on hepatobiliary cancers. This interdisciplinary series is of special value to researchers working on cell biology, immunology, biochemistry, genetics, and practitioners working on oncology and gastroenterology. This is the main concept of Cancer Immunology Project (CIP), which is a part of Universal Scientific Education and Research Network (USERN). This interdisciplinary book will be of special value for researchers, oncologists, and gastroenterologists who wish to extend their knowledge on hepatobiliary cancers.

Hepatobiliary Cancers: An Interdisciplinary Approach

The twelfth volume in the “Interdisciplinary Cancer Research” series, titled “Head and Neck Cancers: An Interdisciplinary Approach,” offers comprehensive reviews on the diagnostic and treatment of head and neck cancers. It begins with an overview of interdisciplinary methods in this field. The book also delves into the role of the microbiome and the evolving understanding of virus-immune system interactions in head and neck cancer. Other chapters focus on circulating tumor cells, extracellular vesicles, and circulating non-coding RNAs. Additionally, it discusses novel therapeutic targets, including lipid levels, oxidative stress, antihypoxic agents, and senotherapy. This volume is part of the Cancer Immunology Project (CIP), part of the Universal Scientific Education and Research Network (USERN), and it is particularly valuable for researchers, head and neck oncosurgeons, and oncologists looking to expand their knowledge in this area.

Head and Neck Cancers: An Interdisciplinary Approach

This book unravels in an easily understandable way the exciting molecular connections between our gut microbiome, i.e. the collective microorganisms that we carry in our digestive system, nutrition and the immune system, and how an imbalance can lead to the development of inflammatory diseases. The totality of these gut microorganisms forms a complex ecosystem within us, consisting of hundreds of different species of bacteria.The author, microbiologist Professor Richard Lucius, introduces the historical context of microbiome research, discusses how our lives have changed in recent decades, and explains the composition and function of the microbiome and its connection to the gut and immune system. The book explains in detail and supported with appealing illustrations how allergies, chronic intestinal inflammation, type 1 diabetes, multiple sclerosis, rheumatoid arthritis, psoriasis and coeliac disease develop. Further chapters deal with the effects of nutrition on our intestinal flora and provide tips on building and maintaining a healthy microbiome. An intact bacterial community utilizes food residues that humans cannot digest and in return provides energy and vital substances. Only together with our inhabitants do we form a well-functioning "superorganism".Our immune system, which has developed over millions of years, is calibrated for a meagre, natural life. Under the influence of our modern way of life, the "Western lifestyle", our inner ecosystem is suffering from a loss of species, similar to our external environment. Highly processed foods, the influence of medication, lack of exercise and little contact with environmental bacteria are promoting this erosion process, which in the long term increases the risk of inflammatory diseases and obesity. As a result, more than 25% of people in modern societies suffer from allergies, autoimmune diseases and food intolerances that hardly existed in the past. This development can be counteracted by a healthy lifestyle that strengthens and diversifies the microbiome.This book is aimed at anyone who wants to understand the complex interplay between our gut microbiome, the immune system, nutrition and disease.The English translation of this volume, originally published in German language, was&nbsp;facilitated by artificial intelligence. A language editor has subsequently revised the text further in an endeavor to refine the work stylistically. The content was later revised by the author for accuracy.&nbsp;

How our Inner Ecosystem Controls the Immune System and Prevents Inflammation

The Microbiome

A Multidisciplinary Approach to Image-Guided Cancer Therapy

Interventional Oncology

This book encompasses the results of two decades of research on locoregional spread of gynecologic cancer, which put forth the ontogenetic cancer field model and its clinical translation in terms of ontogenetic tumor staging and cancer field surgery, particularly for carcinomas of the lower female genital tract. The ontogenetic cancer field model describes the propagation of malignant tumors within distinct permissive tissue regions determined by the development of the tissue from which the neoplasm originated. As the morphogenesis of multicellular animals proceeds stepwise through bifurcational cell fate specification within tissue regions dictated by the positional identity and plasticity of the precursor cell populations, tumor formation during malignant progression occurs as a stepwise process in the reverse direction with regard to positional identity and plasticity.This principle of order can be exploited for diagnosis, treatment and prognosis of cancer in general.The motivation to study in depth the topography of tumor spread arose from the insight that the conventional view of local cancer propagation as an unlimited isotropic process is falsified by numerous inconsistencies with clinical facts. Consequently, conventional cancer therapy based on this model cannot achieve optimal outcomes.The cancer field model and its application in gynecologic oncology has been published in highly ranked journals. However, the complexity of the principles and practice need the format of a well-structured book for their successful transmission to gynecologic surgeons, clinical oncologists, cancer researchers and postgraduate medical students.

Principles and Practice

Cancer Field Surgery in Gynecologic Oncology

This book explores the critical issue of cardiovascular prevention (CVP) in socioeconomically disadvantaged populations, highlighting the stark disparities in access to basic health-preserving tools. Despite significant technological advances in CVP over the past decades, many individuals in low-income countries and deprived segments of high-income nations still lack access to essential care for conditions like diabetes, hypertension, and high cholesterol. This volume sheds light on the prevalence and outcomes of major cardiovascular risk factors—such as obesity, heart failure, and stroke—in these underserved communities and explores potential remedial measures.Contributors from diverse regions bring their extensive research expertise to examine the current status of CVP globally. The chapters cover a range of topics, including the prevalence of risk factors and suggestions for improving cardiovascular health in resource-limited settings. Unlike other publications that focus on cutting-edge developments like polygenic risk scores and new therapies, this book emphasizes fundamental CVP tools that can be applied to the largest segments of the world's population. Readers will gain insights into effective strategies for weight control, healthy diets, smoking cessation, and more.This comprehensive resource is invaluable for students and professionals across various fields, including primary care providers, cardiologists, public health experts, social workers, and economists. It is also suitable for graduate and undergraduate readers interested in public health and healthcare disparities. To ensure broad accessibility, an open access option is&nbsp;available for those with limited financial resources.

Cardiovascular Prevention&nbsp; (CVP) has included important technological advances and determined improvements in morbidity and mortality since the last 70 and 60 years. However, in populations with socioeconomic limited resources even basic health preserving tools such as access to a primary care provider and basic drug therapy for diabetes mellitus, high blood pressure, and high cholesterol are not within the reach of many. There is indeed limited information on the level of CVP available in low-income countries and even in similar segments of deprived populations from high income nations. More information is needed in the prevalence and outcomes in these socioeconomic groups on the major determinants of cardiovascular disease and death: hypertension, diabetes, obesity, heart failure, coronary heart disease, stroke, peripheral vascular disease, and multi-organ involvement. Moreover, in many countries (and not only in those with limited socioeconomic resources) basic preventive measures are still lagging behind (weight control, healthy diet, sedentary lifestyles, smoking cessation, alcohol use). In this book, contributors will review the prevalence of these risk factors as well as discuss possible remedial measures.In the different chapters, scientists from different countries and regions and with extensive research done in CVP in their respective fields will give their views on the status of CVP and suggest feasible remedial steps. Currently, there are many publications on the exciting and more recent developments in CVP, and the new directions undertaken (polygenic risk scores, primordial prevention, new antilipidemic and anti-inflammatory therapies, etc.). This book, in contrast, will go precisely in the opposite direction, defining the most basic and known effective CVP tools applied in the largest segment of the world’s population.This will be a valuable resource for students and professionals from different specialties, such as primary care providers, cardiologists, registered nurses, public health professionals, social workers, and economists. It will also be of interest to readers in the graduate and undergraduate levels. To ensure broad accessibility, an open access option is&nbsp;available for those with limited financial resources.

Global Challenges in Cardiovascular Prevention in Populations with Low Socioeconomic Status

Cancer Survivors in Later Life

Proteomics: A Promising Approach for Cancer Research Volume 2 Proteome signaling dysregulation in cancer, therapeutic interventions, and future perspectives provides an updated overview of scientific knowledge, achievements, and findings in the field of cancer proteomics. The field of cancer proteomics is very dynamic, with emerging trends specifically related to clinical solutions. The book content was developed to help readers get up to speed on the topic and easily apply learnings into research or clinical practice. Volume 2 covers proteome signaling, their dysregulation to therapeutics options and future prospects in 17 different signaling pathways. It capitalizes the enormous interest in proteomics among academics and gives new viewpoints on this topic in cancer treatment. It is a valuable resource for cancer researchers, oncologists, graduate students, and members of biomedical field who are interested in the potential of proteomics in cancer research and treatment.

Proteome Signaling Dysregulation in Cancer, Therapeutic Interventions, and Future Perspectives, vol. 2

Proteomics: A Promising Approach for Cancer Research

Oxford Textbooks In Palliative Medicine

Palliative and hospice care is a specialty that is constantly evolving alongside the needs of its patients. Practitioners must navigate a rapidly growing field to best advocate for and deliver high quality primary and specialty palliative care to persons and families of those living with serious illness. This sixth edition of The Oxford Textbook of Palliative Nursing mirrors developments in Palliative Care, including several new chapters to support the delivery of palliative care to diverse populations. These chapters explore care for patients living with pulmonary, cardiac, liver, renal, and hematologic diseases, as well as chapters on health inequalities, LGBTQ+ communities, rural communities, and care of those with substance use disorders and serious mental illness. Each chapter is rich with tables and figures, case examples for improved learning, and a strong evidence-based practice to support the highest quality of care. The book offers a valuable and practical resource for students and clinicians across all settings of care. The content is relevant for specialty hospice agencies and palliative care programs, as well as generalist knowledge for schools of nursing, oncology, critical care, and pediatrics. Developed with the intention of emphasizing the need to extend palliative care beyond the specialty to be integrated in all settings and by all clinicians caring for the seriously ill, this new edition will continue to serve as the cornerstone of palliative care education.

Oxford Textbook of Palliative Nursing

Recent Results in Cancer Research

After 10 years, this second edition is extensively rewritten and updated and provides a source of information concerning all aspects of medullary thyroid carcinoma, including comprehensive actual references for interested scientists.Medullary thyroid carcinoma (MTC) is a rare unique tumor which differs from other thyroid tumors by originating from the neuroendocrine C-cell, secreting the specific tumor marker calcitonin. MTC is associated in about 25% of cases with multiple endocrine neoplasia type 2, an autosomal dominant familial disorder causing tumors within various endocrine glands. The molecular genetics of tumor development is clarified: hereditary as well as sporadic MTC are linked to mutations in the RET proto- oncogene coding for a tyrosine kinase. These RET mutations serve as a genetic marker for hereditary MTC and allow for prophylactic thyroidectomy in gene carriers. The RET-tyrosine kinase is also a new therapeutic target using selective &nbsp;tyrosine kinase inhibitors improving the outcome of advanced metastasized MTC.&nbsp;This book will be an ideal source of up-to-date information for a wide range of practitioners, including endocrinologists, oncologists, internal medicine specialists, geneticists, and nuclear medicine physicians.

Biology, management, and treatment of sporadic and hereditary MTC

Medullary Thyroid Carcinoma

This book offers a foundational understanding, along with advancements in diagnostics and treatments for melanoma. It underscores the importance of integrating multi-omics approaches for a holistic understanding and explores combination therapies for improving treatment.

This book delves into the complexities of melanoma, offering an in-depth examination of the disease alongside the latest advancements in diagnosis and treatment. The initial chapter provides a comprehensive overview of melanoma, covering its fundamentals and introducing the latest technologies shaping the understanding of the disease. The book introduces advanced molecular diagnostics in identifying targetable mutations and tailoring therapies for personalized and effective melanoma treatment. Additionally, it investigates the role of artificial intelligence in melanoma diagnostics and the advancements in imaging technologies for the monitoring and assessment of melanoma. It also reviews novel, innovative immunotherapeutic approaches designed to enhance the body's immune response against melanoma cells. Further, the book delves into the development and application of targeted therapies and nanomedicine in treating melanoma. A dedicated chapter highlights the advantages of a multi-omics approach, integrating genomic, proteomic, and other omics data to achieve a holistic understanding of melanoma. Towards the end, the book examines the potential of combination therapies to improve treatment outcomes in melanoma. The book is a valuable source for cancer researchers, medical oncologists, and clinicians. Key Features:1) Provides a comprehensive overview of melanoma, covering its fundamentals and introducing the latest diagnostics and treatment strategies.2) Investigates the transformative impact of artificial intelligence in melanoma diagnostics.3) Focuses on immunotherapeutic advancements against melanoma.4) Investigates the advancements in targeted therapies and nanomedicine.5) Explores the synergy of genomics and proteomics in a comprehensive multi-omics approach to melanoma treatment.

Next-Generation Strategies and Solutions

Navigating Melanoma Treatment Challenges

This book is an up-to-date, single-volume, concise reference in ocular oncology. The book is divided into eight chapters. The first chapter is an introduction to oncology in general that covers basic concepts in cell biology, tumorigenesis, the hallmarks of cancer, and tumor pathology. The second chapter discusses the standard treatment methods employed in ocular oncology, including surgical approaches and techniques, treatment with physical energy such as radiotherapy, lasers, and cryotherapy, and the indications and toxicities of systemic and regional drug therapy. The following five chapters demonstrate the examination, classifications, clinical and imaging presentation, and current specific management options of tumors and relevant lesions that involve the eyelid, ocular surface, orbit, uveal tract, and retina. The final chapter highlights the direct and indirect impact of systemic cancers on the ophthalmic tissues and their management.

The book has been richly illustrated with over 350 original figures, schematic representations, and comparison tables.

Principles of Occular Oncology is a must-have resource for ocular oncology specialists and trainees, general ophthalmologists, and allied cancer care specialists who manage ophthalmic tumors.

This book is an up-to-date, single-volume, concise reference in ocular oncology. The book is divided into eight chapters. The first chapter is an introduction to oncology in general that covers basic concepts in cell biology, tumorigenesis, the hallmarks of cancer, and tumor pathology. The second chapter discusses the standard treatment methods employed in ocular oncology, including surgical approaches and techniques, treatment with physical energy such as radiotherapy, lasers, and cryotherapy, and the indications and toxicities of systemic and regional drug therapy. The following five chapters demonstrate the examination, classifications, clinical and imaging presentation, and current specific management options of tumors and relevant lesions that involve the eyelid, ocular surface, orbit, uveal tract, and retina. The final chapter highlights the direct and indirect impact of systemic cancers on the ophthalmic tissues and their management.The book has been richly illustrated with over 350 original figures, schematic representations, and comparison tables.Principles of Occular Oncology is a must-have resource for ocular oncology specialists and trainees, general ophthalmologists, and allied cancer care specialists who manage ophthalmic tumors.

Principles of Ocular Oncology

Springer Biographies

This book chronicles the life and career of Haralampos M. Moutsopoulos,¿an internationally¿renowned professor of medicine and prolific researcher on Sjögren's syndrome and autoimmune rheumatic diseases. In language that is simple and direct, he takes us on a fascinating journey from his first scientific awakenings at a hospital in his native town of Ioannina, Greece, through his university years in Athens and training in the US, to his eventual return to his homeland. A major theme throughout the book, and especially in this second edition, is his impassioned struggle for excellence, meritocracy, and transparency in universities and in the National Health System in Greece. This battle is relentless, especially during critical periods such as the pandemic era, when human life was seriously threatened by the coronavirus and novel therapeutic approaches and bold administrative solutions were urgently required. Peppered with both amusing and unsettling incidents from this lifelong crusade to raise professional standards and against misconduct, the book is a must-read for anyone interested in learning about or entering the medical profession, as well as for those whose goal is to lead an adventurous, passionate life free from fear, prejudice and mediocrity.&nbsp;

My Lifelong Journey into Medicine and Public Service

Passion for Excellence

Advances

Advances in Oncology reviews the year’s most important findings and updates within the field in order to provide practicing oncologists with the current clinical information they need to improve patient outcomes. A distinguished editorial board, led by Dr. Leonidas C. Platanias, identifies key areas of major progress and controversy and invites preeminent specialists to contribute original articles devoted to these topics. These insightful overviews in oncology inform and enhance clinical practice by bringing concepts to a clinical level and exploring their everyday impact on patient care.<ul><li>Contains 25 articles on such topics as adaptive radiation therapy: MRI-guided or CT-guided; neoadjuvant treatment strategies in gastrointestinal stomal tumors; treatment advances in small cell lung cancer; sexual health following diagnosis and treatment of gynecologic cancers; neurocognitive outcomes for childhood cancer survivors; targeting IDH in gliomas; the role of allogeneic stem cell transplant for elderly leukemia patients; bladder-sparing approaches in muscle-invasive bladder cancer; and more</li><li>Provides in-depth, clinical reviews in oncology, providing actionable insights for clinical practice</li><li>Presents the latest information in the field under the leadership of an experienced editorial team. Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews</li></ul>

Advances in Oncology, 2025: Volume 5-1

Cancers in Different Conditions, Cancer Research Methods and ...

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