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Arsham M: The AGT Cytogenetics
Laboratory Manual 4e

The AGT Cytogenetics Laboratory Manual 4e

International Texts in Developmental Psychology

Insights from Genetics and Epigenetics

Psychobiological Development

Plant Pangenomes and Pangenomics summarizes the current state of plant pangenomes and pangenomics as applied in a wide range of plant biology involving the subtopics of genome evolution, phenotypic evolution, population genetics, and evolutionary developmental biology. Explaining the resources and technologies of pangenomics with plant functional genomics, the book also presents precision molecular breeding of crops to produce improved stress-tolerance and climate-smart capacities in an attempt to improve growth, development, enhanced production, and quality. It covers key critical stressors, including temperature, salt, drought, pollutants, pests, fungi, bacteria, and viruses. This book is an complete guide for students, researchers, experts, and professors with its discussions on all aspects of pangenomes and pangenomics, from fundamental and advanced tools and current applications in the plant sciences to plant functional genomics, plant stress physiology, plant biotechnology, plant pathology, and plant breeding.

Plant Pangenomes and Pangenomics

Chapman & Hall/CRC Computational Biology Series

RNA Structure, Kinetics, and Rational Design is a comprehensive treatment of computational methods concerning the secondary structure, folding kinetics and rational design of RNA. This book provides the nuts, bolts and tools to take the next steps in computational RNA synthetic biology.

Comprising two volumes, RNA: Computational Methods for Structure, Kinetics, and Rational Design is a comprehensive treatment of computational methods concerning the secondary structure, folding kinetics and rational design of RNA.Volume One concerns energy and structure and is divided into five chapters. Chapter 1 describes the molecular structure of ribonucleotides, basic classes of RNA and databases of RNA sequences and structure. Chapter 2 presents the basic concepts of thermodynamics, since thermodynamics-based algorithms constitute an essential tool in rational design of functional RNA molecules. Chapter 3 describes how empirical secondary structure energy parameters are obtained from ultraviolet absorbance experiments via Van 't Hoff plots and least-squares data fitting. Chapter 4 describes methods from combinatorics, automata and formal language theory, and complex analysis. Chapter 5 provides an overview of some of the most important thermodynamics-based algorithms related to secondary structure. Exercises and solutions are provided at the end of every chapter and source code is available at the book's website (sometimes including computer programs using Python and extensions Numpy and Scipy).This book provides the nuts, bolts and tools to take the next steps in computational RNA synthetic biology. It is perfect for advanced undergraduate, graduate and post-graduate readers having analytical interests and skills from areas such as physical chemistry, physics, mathematics, computer science, and statistics.

RNA: Computational Methods for Structure, Kinetics, and Rational Design: Volume One

"This book uncovers the ways natural selection leads to imperfection in humans and the implications of this for our understanding of how evolution works and human biology and health. The simplest version of evolution frames it as a gradual process that leads to constant improvement. This view holds that natural selection drives toward "perfection." Mutations in an organism's genome either harm or help its ability to reproduce; harmful ones don't last while beneficial ones are passed on and spread throughout a population. As Laurence Hurst argues in this book, the reality is far more complicated. This is particularly true for humans at the level of our DNA. Why, for example do we need so many sperm to fertilize one egg? Or why do we have a high rate of genetic disease? And why does much of our DNA appear to be pointless? These imperfections do not make sense when we assume that evolution is a constantly improving process, yet the more scientists study our genome the more they see things that look like imperfections. How, then, are they explained? After carefully introducing readers to what he means by perfection and imperfection and providing basic information about DNA, Hurst provides evidence for why the human genome retains imperfections. He argues that our small populations, high mutation rates, and mode of reproduction leave us vulnerable to all sorts of problems. In dissecting the evolution of our imperfection, Hurst illuminates what scientists are learning about the human genome and why it seems to cause so many issues despite our success as a species. Finally, despite what we might call our "rotten lot," evolutionarily speaking, we have our big brains and medicine to combat genetic disease and, at the end of the book, Hurst reviews what scientists are learning about curing genetically based diseases"--

How understanding our genetic imperfections can change our view of evolution and enrich what it means to be human

The Science of Why We Aren’t and Can’t Be Perfect

The Evolution of Imperfection

The main focus is on the analysis of next-generation-sequencing assays, both for the interpretation of the DNA sequence per se and for the study of gene regulation and epigenomics.

The main focus is on the analysis of next-generation-sequencing assays, both for the interpretation of the DNA sequence per se and for the study of gene regulation and epigenomics.

Principles of Computational Genomics

Insect Anatomy: Structure and Function provides both morphological and anatomical descriptions of insect tissues and organs and the underlying genetic mechanisms of their function using updated methods. Insects play important roles in diverse ecosystems, with subsequent, tremendous impacts on human society through disease, agriculture effects, and more. Both beneficial and detrimental insect species continuously challenge agriculture and medicine. Written by international experts of insect morphology and anatomy, this book offers concise descriptions of all parts of an insect's anatomy, including the brain and nervous system, tracheal system, blood, reproductive organs, and kidney system.

Structure and Function

Insect Anatomy

Nanomaterial-Plant Interactions

Nanomaterials for Enhanced Plant-Based Food Production a new release in the Nanomaterial-Plant Interactions series, presents up-to-date insights on the use of nano-enabled agricultural tools from nanofertilizers to nanosensors, including how to balance safety and environmental impact concerns to ensure optimal utilization. The book provides a range of solution options and guides the reader in identifying the most appropriate choice. With state-of-the-art, broad coverage of recent and potential applications, this book covers the most recent advances in the application of nanotechnology toward fulfilling the world's food demands for present and future generations.

Nanomaterials for Enhanced Plant-Based Food Production

Princeton Series in Theoretical and Computational Biology

"A powerful new approach to interpreting population-genetic data in evolution and ecologyPopulation genetics uses statistical analysis to catalog genetic variation among populations and species. Summary statistics computed from allele frequencies-mathematical functions that measure features of genetic similarity and diversity-are key to this global effort. Yet despite their widespread use in evolutionary biology, ecology, and conservation biology, their mathematical properties have largely been overlooked. This book shows how to use the mathematical bounds on summary statistics to make better interpretations of population-genetic data.Noah Rosenberg discusses how the behavior of these statistics depends not only on the biology of the populations they seek to describe but also on the mathematical properties of the functions used to compute them, properties that produce constraints on the values of the statistics and influence their interpretation. Focusing on the concept of homozygosity-a quadratic function of allele frequencies in a population-he demonstrates how to account for mathematical constraints when measuring genetic similarity and diversity. Rosenberg illustrates the results using examples from empirical data and shares strategies that readers can use to apply this mathematical perspective to different kinds of summary statistics, including those for measuring biodiversity in ecological communities.Drawing inspiration from Charles Darwin, who marveled at evolution's "endless forms most beautiful and most wonderful," this book presents a groundbreaking approach to the study of genetic variation. It is sure to stimulate new research in population biology and deeper thinking about the meaning and interpretation of essential measurements of the world's genomes"--

A powerful new approach to interpreting population-genetic data in evolution and ecology Population genetics uses statistical analysis to catalog genetic variation among populations and species. Summary statistics computed from allele frequencies—mathematical functions that measure features of genetic similarity and diversity—are key to this global effort. Yet despite their widespread use in evolutionary biology, ecology, and conservation biology, their mathematical properties have largely been overlooked. This book shows how to use the mathematical bounds on summary statistics to make better interpretations of population-genetic data. Noah Rosenberg discusses how the behavior of these statistics depends not only on the biology of the populations they seek to describe but also on the mathematical properties of the functions used to compute them, properties that produce constraints on the values of the statistics and influence their interpretation. Focusing on the concept of homozygosity—a quadratic function of allele frequencies in a population—he demonstrates how to account for mathematical constraints when measuring genetic similarity and diversity. Rosenberg illustrates the results using examples from empirical data and shares strategies that readers can use to apply this mathematical perspective to different kinds of summary statistics, including those for measuring biodiversity in ecological communities. Drawing inspiration from Charles Darwin, who marveled at evolution’s “endless forms most beautiful and most wonderful,” this book presents a groundbreaking approach to the study of genetic variation. It is sure to stimulate new research in population biology and deeper thinking about the meaning and interpretation of essential measurements of the world’s genomes.

Quadratic Forms Most Beautiful

Mathematical Properties of Population-Genetic Statistics

Genomic and Precision Medicine in Clinical Practice

Medical and Health Genomics of South Asia, a new volume in the Genomic and Precision Medicine in Clinical Practice series, offers a thorough discussion of medical genomics as applied across South Asian nations, from India to Pakistan, Bangladesh, Sri Lanka, and Nepal, as well as in South Asian populations abroad. Here, global chapter authors consider genomic variation and the population heterogeneity of genetic, infectious, and lifestyle diseases in South Asia, along with successful modes of population health management for these inherited disorders and other applications of clinical genomics for improved individual health in the region. Adopting an applied approach, this book first reviews basic genomic models and population study formats, as well as the anthropological and genetic history of South Asia. The following sections examine genomic epidemiology and population health in the South Asian context; examples of genomic medicine's use in combating major health challenges in the region; genomic healthcare infrastructure; and related social, ethical, legal, and economic aspects central to impactful genomic medicine.

Medical and Health Genomics of South Asia

Advances in Cancer Research

Cerebral Metastases: Translational Advances, Evaluation and Management: Volume 165

'The fascinating story of ancient words ... new revelations await' The Guardian'A magisterial feat' New Scientist________________________________

How One Ancient Language Went Global

Proto

Pathophysiology, Management, and Emerging Therapies

Gastrointestinal Inflammations and Gut Microbiota

The AGT Cytogenetics Laboratory Manual 4e

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