The book delves into the realm of biomaterials with a strong focus on sustainability, offering insights into their diverse applications in advanced therapeutics, and, diagnostics. Tackling cutting-edge topics, it explores the latest developments in green biomaterials for biomedical implants and tissue engineering, emphasizing sustainability in nanocomposite synthesis, properties, and applications. The book also addresses the groundbreaking concept of biodegradable and biofriendly transient devices for sustainable monitoring and healing. Further, it highlights the crucial role of biodegradable scaffolds in engineering living tissues and discusses gene-activated matrices for tissue engineering and regenerative medicine. Various chapters delve into specialized applications, such as tissue-engineered cartilage products, green biomaterials for innovative drug delivery, and 3D printed biodegradable metals in orthopedics and stomatology. The book also explores the use of bioresorbable polymers in advancing minimally invasive surgical procedures and customizing medical devices for personalized medicine. Additionally, it sheds light on the integration of nanobioengineered platforms in electrochemical biosensors for disease diagnosis, antimicrobial biomaterials in dental healthcare, silk-based biomaterials for regenerative medicine and drug delivery, and the utilization of plant-derived biomaterials in cardiac tissue repair. This comprehensive volume not only provides a snapshot of the latest advancements in the field but also underscores the pivotal role of green biomaterials in shaping the future of healthcare technologies.