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Precision Medicine in Pediatric Health

International Texts in Developmental Psychology

Insights from Genetics and Epigenetics

Psychobiological Development

Chapman & Hall/CRC Computational Biology Series

The main focus is on the analysis of next-generation-sequencing assays, both for the interpretation of the DNA sequence per se and for the study of gene regulation and epigenomics.

The main focus is on the analysis of next-generation-sequencing assays, both for the interpretation of the DNA sequence per se and for the study of gene regulation and epigenomics.

Principles of Computational Genomics

Harnessing Genomic Tools for Crop Improvement: A Software User Manual for Transforming Geneticists to Genomicists is an important resource for crop improvement software users. This book provides essential information to understand the molecular data stems from the molecular genetics and breeding experiments. It presents various genomics-related software encompassing genetic diversity (DARWIN), QTL mapping (QTL Cartographer), Genome-wide association mapping (GAPIT), Haplotype analysis (DNAsp), Marker-assisted breeding (GGT), and others in a step-by-step format. It also looks at the latest bioinformatic tools such as databases, BLAST, primer designing and sequence alignment. Furthermore, this book provides definitions and clarifies the terminology and interpretation of the outputs (Tables and Figures) of each software through case studies. This book provides a single comprehensive user manual for crop improvement software tool users, making it an invaluable asset for scientists, students, and post-doctoral fellows with an interest in plant and animal genetics.

A Software User Manual for Transforming Geneticists to Genomicists

Harnessing Genomic Tools for Crop Improvement

For decades, Dalton Conley tried to answer the big social questions-about why groups hold together, about inequality, and more-through the traditional tools of his first field, sociology. He eventually found that those tools could take him only so far. So he went back to school and got another PhD-in biology. Now, in The Social Genome, Conley explains how the new field he has helped to pioneer, sociogenomics, will upend our world. The key is the polygenic index, which allows us to analyse DNA to broadly predict a child's future-not just their height or their weight, but how they may be expected to fare in school, and much more. He argues that we should no longer think of nature versus nurture but of how our genes need nurture to work and how, in turn, our environments are made partly from the genes of other people. The implications of this new science-for our sense of self, for our social policies-are vast.

The New Science of Nature and Nurture

The Social Genome

The theme of Introduction to Genetics is the progression from molecules (DNA and genes) to processes (gene expression and DNA replication) to systems (cells, organisms and populations). The molecular approach is particularly suitable for students for whom genetics is part of a broader program in biology, biochemistry or biomedicine.

The theme of Introduction to Genetics is the progression from molecules (DNA and genes) to processes (gene expression and DNA replication) to systems (cells, organisms and populations). The molecular approach is particularly suitable for students for whom genetics is part of a broader program in biology, biochemistry or biomedicine.

A Molecular Approach

Introduction to Genetics

Genome Modified Plants and Microbes in Food and Agriculture

CRISPR for Climate-Smart and Sustainable Agriculture summarizes the current genome editing technology being used in food and energy crops. It presents methods and applications of CRISPR tools for breeding climate-smart and stress-tolerant crops that are better able to resist biotic and abiotic stressors due to climate change. Gene editing tools are increasingly seen as options for improving plant health and productivity. CRISPR is one such emerging and quickly advancing crucial technology for the research field of plant physiology, plant molecular biology, and crop breeding. CRISPR for Climate-Smart and Sustainable Agriculture focuses on genetic engineering using CRISPR technology for precision breeding of crops to achieve climate resilience, stress tolerance, and higher yield. Organized by specific plant challenges, this book presents expert insights from around the globe, providing updated knowledge of CRISPR with an emphasis on facing climate change and supporting sustainable agriculture. This volume in the Genome Modified Plants and Microbes in Food and Agriculture series will be valuable for researchers, academics, and advanced-level students seeking to understand and advance the use of CRISPR technologies toward the UN Sustainable Development Goals and the Paris Climate Agreement.

CRISPR for Climate-Smart and Sustainable Agriculture

This new edition of Gene Control is the only textbook offering a complete account of gene control for both prokaryotic and eukaryotic organisms. The core objective of this edition is to educate students about the fundamental principles and mechanisms governing gene expression, regulation, and function.

This new edition of Gene Control is the only textbook offering a complete account of gene control for both prokaryotic and eukaryotic organisms. The core objective of this edition is to educate students about the fundamental principles and mechanisms governing gene expression, regulation, and function.

Gene Control

Advances in Cancer Research

Cerebral Metastases: Translational Advances, Evaluation and Management: Volume 165

PSYCHOBIOLOGICAL DEVELOPMENT

Translational Epigenetics

In recent years, the field of epigenetics has grown significantly, driving new understanding of human developmental processes and disease expression, as well as advances in diagnostics and therapeutics. As the field of epigenetics continues to grow, methods and technologies have multiplied, resulting in a wide range of approaches and tools researchers might employ. "Epigenetics Methods, Second Edition" offers comprehensive coverage of the tools that enhance translational epigenetics studies. This edition provides updated and revised chapters, as well covering new topics such as, MALDI-TOF-MS for analysis of DNA methylation, assessment of histone modifying enzymes and RIP assay for lncRNA binding. Here, across thirty-six chapters, specialists offer step-by-step overviews of methods used to study various epigenetic mechanisms, as employed in basic and translational research. Leading the reader from fundamental to more advanced methods, the book begins with an overview of epigenetics methods, then provides thorough instruction in DNA methylation techniques and gene or locus-specific methylation analyses. Followed by histone modification methods, chromatin evaluation, enzyme analyses of histone methylation, and studies of non-coding RNAs as epigenetic modulators. Recently developed techniques and technologies discussed include single-cell epigenomics, epigenetic editing, computational epigenetics, systems biology epigenetic methods, and forensic epigenetic approaches. Epigenetics methods currently in-development, and their implication for future research, are also considered in-depth. In addition, as with the wider life sciences, reproducibility across experiments, labs, and subdisciplines is a growing issue for epigenetics researchers. This volume provides consensus-driven methods instruction and overviews. Tollefsbol and contributing authors survey the range of existing methods; identify best practices, common themes, and challenges; and bring unity of approach to a diverse and ever-evolving field.

Epigenetics Methods

An anthropologist uncovers new evidence for the evolutionary origins of human longevity-and explains why growing old is an opportunity, not a burdenOur ability to live for decades may seem like a modern luxury made possible by clean water and advances in medicine. In fact, human longevity is a legacy of our unique evolutionary path as a species. Seven Decades challenges the belief that life in the past was "nasty, brutish, and short," tracing how our capacity for long life came to be and transforming how we think about aging. Blending vivid storytelling with cutting-edge science, anthropologist Michael Gurven weaves tales from his years of field experience among Indigenous societies whose diet and traditional lifeways are closer to how we all lived prior to industrialization, demonstrating how these communities are relatively free of the chronic diseases of aging such as heart disease, dementia, and diabetes. He provides compelling evidence that our longevity first evolved among our hunting and gathering ancestors and shows how the human body was built to last around seven decades. At a time when people are more likely to live to old age than ever before, Gurven discusses how we can harness this amazing evolutionary feat through a shift in societal values, one that balances self-reliance with interdependence, nurtures multigenerational ties, prioritizes women's health and longevity, and enables us to rediscover the wisdom of our elders. Sharing bold new perspectives on human ageing, Seven Decades draws important lessons from our ancestral history, bridging the past with the present to reveal what healthy, happy, and productive old age could look like for all generations.

How We Evolved to Live Longer

Seven Decades

Current Topics in Developmental Biology

Cell Migration in Development: Volume 165

Precision Medicine in Pediatric Health

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