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Nanotechnology in Wound Healing

Innovations, Applications, and Future Perspectives

Written by two pioneers in the field, this book offers the first practical and complete introduction to the basic principles of photoacoustic imaging in biomedicine. It covers basic tissue optics, radio frequency properties, physics of ultrasound in tissue, photoacoustics theory, photo acoustic computed tomography, and photoacoustic scanning tomography with ultrasonic resolution. Capturing the state of the art in photoacoustic imaging for biomedical applications, each chapter presents discussions of current imaging systems, spatial resolutions, and limitations of each approach.

Written by two pioneers in the field, this book offers the first practical and complete introduction to the basic principles of photoacoustic imaging in biomedicine. It covers basic tissue optics, radio frequency properties, physics of ultrasound in tissue, photoacoustics theory, photo acoustic computed tomography, and photoacoustic scanning tomography with ultrasonic resolution. Capturing the state of the art in photoacoustic imaging for biomedical applications, each chapter presents discussions of current imaging systems, spatial resolutions, and limitations of each approach.

Photoacoustic Tomography

Chromatographic Science Series

Active chemical compounds in the pharmaceutical products existing on the market need to be characterized with respect to their properties, or compared to other similar products, already available for direct use. The book describes sampling methodologies, preparation methods, separation possibilities and assay of these compounds at low concentration levels in complex matrixes. The steps covered are taken before launching a new pharmaceutical product on the market for estimating its pharmacokinetic behavior, or before authorizing for marketing of a generic pharmaceutical product.

Active chemical compounds in the pharmaceutical products existing on the market need to be characterized with respect to their properties, or compared to other similar products, already available for direct use. The book describes sampling methodologies, preparation methods, separation possibilities and assay of these compounds at low concentration levels in complex matrixes. The steps covered are taken before launching a new pharmaceutical product on the market for estimating its pharmacokinetic behavior, or before authorizing for marketing of a generic pharmaceutical product.

Analytical Aspects of Bioequivalence

This book highlights the basic concepts and equations for bioengineering flow processes. Physical concepts and meanings are emphasized while rigorous derivations are simplified, making it easier for self learning on some biological and medical flow processes. The well known Bernoulli equation in hydraulics is extended for pulsating flows, peristaltic flows and cardiac pumping. The dimensional analysis, model law and dimensionless equations can be related to computational models and experimental observations. The velocity vector imaging stored in echocardiograms can be used to analyze the pumping characteristics of the ventricular contraction. New topics included oxygen transport in membrane oxygenator and micro mixing of blood flow in capillary channels.

Bioengineering Fluid Mechanics

Pharmaceutical QbD with Design of Experiments: Statistical Tools and Applications in Drug Delivery Systems offers comprehensive coverage of best practices in pharmaceutical manufacturing. The first section discusses the principles and basics of Quality by Design (QbD). Part two covers the foundational statistical principles and tools for the Design of Experiments (DoE). Section three is dedicated to the applications of QbD for conventional formulations. The next section provides ample coverage of applications to Novel Drug Delivery Systems (NDDS), including micro and nano-particles. The final section discusses the application of QbD for the optimization of pharmaceutical processes and equipment. Researchers in pharmaceutical manufacturing will benefit from this thorough statistical review, while students in this field will gain practical insights the experienced chapter authors provide in case studies. Industry professionals can find solutions to their particular problems within the insights and strategies shared in this book.

Statistical Tools and Applications in Drug Delivery Systems

Pharmaceutical QbD with Design of Experiments

Advances in Magnetic Resonance Technology and Applications

Advanced MR Techniques for Neurodegenerative Diseases covers state of the art developments in physiologic, metabolic, functional, and microstructural MRI of the brain. It provides an overview of these approaches and includes dynamic contrast enhanced (DCE) MRI, dynamic susceptibility contrast (DSC) MRI, arterial spin labeling (ASL), chemical exchange saturation transfer (CEST) MRI, magnetic resonance spectroscopy (MRS), resting state functional MRI (rsfMRI), microscopic diffusion imaging, and quantitative susceptibility mapping (QSM). Chapters then follow that present the application of these methods to Alzheimer’s Disease and vascular dementia, small vessel disease, Parkinson’s Disease, Lewy body dementia, Huntington’s Disease, Amyotrophic Lateral Sclerosis, and Multiple Sclerosis. Advanced MR Techniques for Neurodegenerative Diseases is a comprehensive resource on the latest advanced MR techniques and their application to neurodegenerative diseases, suitable for MR engineers and physicists as well as clinicians and neuroscientists who use MR techniques for diagnosis and research.

Advanced MR Techniques for Neurodegenerative Diseases: Volume 13

Radiography, or X-ray imaging, is not only the first medical imaging modality but continues to be the most commonly used. This book provides complete coverage of the fundamentals, from technology to image acquisition, storage, display, analysis, and quality assurance methods to applications for improved disease detection and diagnosis. It is written for anyone looking for a comprehensive, accessible treatment of the basic physics and technology, radiological principles, imaging methodologies, applications, and their impact on the clinical practice of radiography.

Radiography, or X-ray imaging, is not only the first medical imaging modality but continues to be the most commonly used. This book provides complete coverage of the fundamentals, from technology to image acquisition, storage, display, analysis, and quality assurance methods to applications for improved disease detection and diagnosis. It is written for anyone looking for a comprehensive, accessible treatment of the basic physics and technology, radiological principles, imaging methodologies, applications, and their impact on the clinical practice of radiography.

Technology, Imaging, and Applications

Digital Radiography

Basic Neurochemistry: Principles of Molecular, Cellular, and Medical Neurobiology, Ninth Edition is a classic advanced neurochemistry and neurobiology textbook that has a renewed focus on clinical applications. The early chapters focus on fundamental membrane chemistry, cellular signaling, and development of the nervous system. Later chapters cover cell injury and inflammation, neurodegenerative diseases, sensory transduction, and neural processing/behavior. By understanding mechanisms at the molecular and systems level, scientists can develop new pharmacotherapies to treat diseases such as Alzheimer's Disease, Parkinson's Disease, Multiple Sclerosis as well as neuropsychiatric diseases (e.g., schizophrenia, depression, pain, addictions). This book provides a foundation of all key principles of neurochemistry and neurobiology--within the context of human diseases--for advanced students and graduate students in neuroscience, biomedical sciences, as well as clinical neuroscientists and neurologists.

Principles of Molecular, Cellular, and Medical Neurobiology

Basic Neurochemistry

A follow-up to the experimental and instrumental aspects described in Basic Principles of Analytical Ultracentrifugation, the volume Sedimentation Velocity Analytical Ultracentrifugation: Discrete Species and Size-Distributions of Macromolecules and Particles describes the theory and practice of data analysis. Mathematical models for the sedimentation process and the evolution of detected signals are developed in a comprehensive framework, jointly with the description of current and historical strategies for how to extract from noisy experimental data the physical parameters of interest, such as size, mass, and shape, composition, and polydispersity of sedimenting particles. The methods are extensively illustrated, and supported with practical applications, as well as cross-references where to find the methods in the public domain software SEDFIT and SEDPHAT. The systems covered are discrete or polydisperse mixtures of sedimenting molecules or particles in dilute solution, such as proteins and other biomolecules and their stable complexes, man-made polymers, and nanoparticles, observed in different optical systems. These methods form the essential foundation for the analysis of dynamic interacting systems, which are covered in a separate volume.

A follow-up to the experimental and instrumental aspects described in Basic Principles of Analytical Ultracentrifugation, the volume Sedimentation Velocity Analytical Ultracentrifugation: Discrete Species and Size-Distributions of Macromolecules and Particles describes the theory and practice of data analysis. Mathematical models for the sedimentation process and the evolution of detected signals are developed in a comprehensive framework, jointly with the description of current and historical strategies for how to extract from noisy experimental data the physical parameters of interest, such as size, mass, and shape, composition, and polydispersity of sedimenting particles. The methods are extensively illustrated, and supported with practical applications, as well as cross-references where to find the methods in the public domain software SEDFIT and SEDPHAT. The systems covered are discrete or polydisperse mixtures of sedimenting molecules or particles in dilute solution, such as proteins and other biomolecules and their stable complexes, man-made polymers, and nanoparticles, observed in different optical systems. These methods form the essential foundation for the analysis of dynamic interacting systems, which are covered in a separate volume.

Sedimentation Equilibrium Analytical Ultracentrifugation

Optical Instrumentation

Basic, Applied and Clinical Aspects

Systemic Lupus Erythematosus

Skin, Sensing, and Structures

Humanizing Artificial Touch

Woodhead Publishing Series in Biomaterials

Advances in Biomaterials for Drug Delivery: Properties, Clinical Applications and Challenges comprehensively reviews various biomaterials and biomaterial-derived carrier systems, with a specific focus on their application in drug delivery, and their clinical and regulatory challenges. A broad range of biomaterials for drug delivery are covered, including natural biomaterials, inorganic biomaterials, synthetic biomaterials, 3-D/4-D printed biomaterials, metal-based biomaterials, and polymeric and lipidic biomaterials. Various drug delivery approaches are detailed, from pulmonary and transdermal through to oral and systemic. Key to translational success of these novel platforms are the regulatory and clinical aspects of biomaterials development and application; these aspects are covered in each chapter, providing vital insight required to make informed decisions. Advances in Biomaterials for Drug Delivery: Properties, Clinical Applications and Challenges is an interesting resource for researchers and academics in the fields in biomaterials, materials science, polymer science, and pharmaceutical science, as well as clinicians and R&amp;D groups with an interest in the development of novel biomaterials for drug delivery.

Advances in Biomaterials for Drug Delivery: Properties, Clinical Applications and Challenges

Nanotechnology in Wound Healing

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