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Krendyukov A: Medical Affairs’
Fundamentals: The Next Generation

Medical Affairs’ Fundamentals: The Next Generation

The Encyclopedia of Lipidomics will present a complete overview of the field from fundamentals to new discoveries and from concepts, theories and experimental techniques to clinical and industrial applications. The book will develop with the active involvement of a strong editorial board comprised of leaders from the field. The Encyclopedia of Lipidomics intends to be a comprehensive reference resource serving to bridge the gap between clinical and basic science investigators and provide authoritative and digested information to students, scientists as well as non specialists. The book will have an edge over protocol type of works and databases in terms of having wider coverage through rigorous essays on terms, concepts, experimental and analytical techniques, applications and new challenges. Since lipidomics has strong linkages with several of the other biomedical and life sciences disciplines, the proposed encyclopedia will have a wide audience including graduate students, researchers and different levels of scientists in biomedicine, cellular and molecular biology, bioengineering, physiological and biochemistry, and pharmacology across both academia and industry.

The Encyclopedia of Lipidomics will present a complete overview of the field from fundamentals to new discoveries and from concepts, theories and experimental techniques to clinical and industrial applications. The book will develop with the active involvement of a strong editorial board comprised of leaders from the field.  The Encyclopedia of Lipidomics intends to be a comprehensive reference resource serving to bridge the gap between clinical and basic science investigators and provide authoritative and digested information to students, scientists as well as non specialists.  The book will have an edge over protocol type of works and databases in terms of having wider coverage through rigorous essays on terms, concepts, experimental and analytical techniques, applications and new challenges.  Since lipidomics has strong linkages with several of the other biomedical and life sciences disciplines, the proposed encyclopedia will have a wide audience including graduate students, researchers and different levels of scientists in biomedicine, cellular and molecular biology, bioengineering, physiological and biochemistry, and pharmacology across both academia and industry.

Encyclopedia of Lipidomics

Sustainable Development Goals Series

Critical Reflections and Visions of Equity at the Research-Practice Interface

Transforming Global Health Partnerships

Christies & Agathas Fälle

Cozy Crime für LeseanfängerDer erste Fall der unterhaltsamen Detektivserie um die Zwillingsschwestern Christie und AgathaAls Agatha versehentlich eine wichtige wissenschaftliche Entdeckung isst (versteckt in einem Sandwich!), beginnt für die Zwillinge Agatha und Christie ein Wettlauf mit der Zeit, um herauszufinden, wer den Ruf des berühmten Arztes Sir Alexander Fleming zu ruinieren versucht, und um seine wichtigste Erfindung zu retten. Zum Glück steht ihnen auch der weltbekannte Autor Sir Conan Doyle zur Seite.<ul><li>Erster Band der neuen Krimi-Reihe für Leseanfänger </li><li>Cozy Crime mit Witz und 1920er-Jahre-Flair </li><li>Mit kleinem Infoteil zu den historischen Figuren</li><li>Super sympathische Charaktere und spannende Fälle in einfacher Sprache</li></ul>Fortsetzung im Sommer 2025Zu diesem Buch finden Sie Quizfragen auf antolin.de

Detektivagentur Christie & Agatha – Ein Beweisstück verschwindet

The patch clamp technique is one of the most important electrophysiological methods in use today. Its application in basic biomedical research has provided significant insights into the function and properties of ion channels, making it equally indispensable in applied pharmacological research.&nbsp;This book is the English edition of the popular German introduction to the patch clamp technique.&nbsp;This introductory book serves as a practical guide for teachers and students, offering clear and practical instructions on patch clamp recordings. The authors provide essential information to establish and successfully apply this method in the laboratory. The book covers the basics of measurements, the detailed setup of a patch clamp rig and how to carry out typical recordings. It also includes concrete tips and tricks to help with troubleshooting, making it an indispensable resource.&nbsp;The book not only highlights the enormous potential of the method for the study of ion channels and cell signaling, but also provides an introduction to the major developments and variations of the technique.The book is aimed at advanced students of biology, biochemistry, medicine, pharmacy and related disciplines as well as scientists who want to better understand and/or acquire the technique.&nbsp;&nbsp;About the AuthorsFabian Roth is a neurobiologist who researches and teaches at the Institute of Basic Medical Sciences (IMB) at the University of Oslo, Norway.Markus Numberger is a biologist and works as a freelance science writer in the fields of medicine, pharmacy and biology.&nbsp;Andreas Draguhn is a medical doctor and lecturer at the University of Heidelberg, Germany.

Mastering the Patch Clamp Technique: A Practical Guide

Dieses Fachbuch bietet eine vollständige und detaillierte Darstellung aller wichtigen Medikamente und Wirkstoffe zur intravitrealen Applikation in der Ophthalmologie. Dabei wird unter anderem auf VEGF-Inhibitoren, Corticosteroide und Antibiotika eingegangen. Eine übersichtliche Präsentation in alphabetischer Auflistung – von A bis Z – macht die verschiedenen Wirkstoffe schnell auffindbar. So können Indikationen, Dosierungen oder pharmakologische Eigenschaften rasch nachgeschlagen werden. Hintergrundinformationen zu Handelsnamen, Biosimilars und Zulassungsdetails zur intravitrealen Therapie helfen zudem, den Überblick über die verfügbaren Wirkstoffe zu behalten. Systematische Übersichtstabellen am Ende des Buches strukturieren die Medikamente nach chemischer Eigenschaft, Indikation oder Wirkweise.Ein detaillierter Leitfaden mit fundiertem Wissen über die intravitrealen Medikamente und ihre Anwendung.Über den Autor:Prof. Dr. med. Antonio Bergua, FEBO, ist Oberarzt an der Augenklinik des Uniklinikums Erlangen und verantwortlich für die Uveitis-Sprechstunde. Er hat langjährige Erfahrung in der Indikationsstellung und Anwendung intravitrealer Medikamente. Bereits 2017 veröffentlichte er das Buch „Das menschliche Auge in Zahlen“, ebenfalls beim Springer-Verlag.

Intravitreale Medikamente

Reviews of Physiology, Biochemistry and Pharmacology

This book presents the essential electrical events that shaped the creation of a planet that can support life, shaped membrane formation, single cell formation, single cell wound healing, multicellularity, epithelial tissues, basement membranes and many other biological events. This book aims to do three things: 1) enhance awareness of the lesser known contributions of electrical forces in life, 2) develop a picture of the all-embracing impact of electricity throughout biology and 3) as a consequence pave the way for new technologies that target these less well known electrical events.

This book introduces a balanced and scientific thesis, that electrical forces are used ubiquitously throughout biology. It serves as a valuable resource for anyone interested in understanding the role of electricity in shaping life. The reader may also find how SARS-CoV-2 used electricity to infect humans and how we might tackle dementia.

Electrical Forces Govern Great Swathes of Biology

No Electricity, No Life

Long acting injectables and implants (LAI) are known to improve patient adherence and treatment outcomes. They reduce costs for the healthcare system and ensure sustainable sales for pharmaceutical companies. LAI are usually administered intramuscularly (IM) or subcutaneously (SC). In this way, the drug is released from its depot in a controlled manner over a longer period of time (e.g., a few days to a year). There is a trend toward increasing interest in the development of long-acting drugs for local administration versus systemic administration of depot products (i.e., IM or SC injection). This is leading to finding new ways of administration of the depot formulation, intra-ocular, intra-articular, pri-tendon etc. Therefore, it is expected that more drugs based on LAI formulations will enter the clinical phase in the future. Due to many benefits in adherence, efficacy, and safety of the treatment up until now around 50 brand name medicines using different biodegradable long-acting technology have received FDA approval. Manufacturing of LAI involves many steps with their unique challenges, which is why pharmaceutical companies consider them to be complex formulations to develop. Most of the published papers and books in this field are written by scientists who never worked in industry and whose knowledge on the topic is limited to small scale formulation screening. Therefore, this book aims to address the challenges of the development of biodegradable LAI from an industrial perspective.

An Industry View

Biodegradable Long Acting Injectables and Implants

“Revitalizing Health Care Ethics&nbsp;&nbsp;presents a clear and empathic strategy for clinicians to take responsibility and trust their judgment as they confront ethical questions in the care of patients. This is a must read for clinicians and bioethicists, students and trainees, their teachers, and anyone concerned about the state of compassionate caregiving and the quality of patient care today.” –&nbsp; Allan M. Brandt, Harvard University, USA“This is a book that clinicians are sure to enjoy. It communicates a deep respect for clinicians and for their existing skills and capacities, including ethical capacities. It deserves to reach a wide audience of students, trainees, clinicians, and educators.” - Per Olav Vandvik, MD, PhD, University of Oslo, NorwayThis open access book explores the origins and development of the clinician’s moral voice and&nbsp;how that voice is embedded in the informal ethical discourse of everyday health care. This moral voice, developed over the course of a lifetime—including through professional education and practice—enables clinicians to understand and address the ethical issues that arise in their everyday work with patients, families, and colleagues. The early chapters explain how health care students move from outsiders to insiders—members of the distinct moral and professional communities that define each particular field of health care. The book describes how students, trainees, and clinicians draw on and extend their own existing intellectual, emotional, and moral capacities, and how they use these capacities to address the daily challenges, ethical and otherwise, that arise in the clinic. This approach is designed both to empower clinicians and to inform bioethicists and others in their attempts to work more effectively within clinical settings.This book is available open access under a CC BY-NC-ND 4.0 license.Stephen Scher is Senior Consulting Editor, Harvard Review of Psychiatry, and Lecturer in Psychiatry, McLean Hospital/Harvard Medical School, USA, and University of Sydney Medical School, Australia.Kasia Kozlowska is a child and adolescent psychiatrist at The Children’s Hospital at Westmead and Clinical Professor in Psychiatry and Child &amp; Adolescent Health at the University of Sydney Medical School, Australia.

The Clinician’s Voice

Revitalizing Health Care Ethics

Synthesis Lectures on Biomedical Engineering

This book presents the recent developments in immunomodulatory biomaterials for cell-based therapies in various diseases, including diabetes, cancer, cardiovascular disease, and bone regeneration. The authors first cover the fundamentals of conventional immunology and immunomodulation, before focusing on the history, advantages, and challenges of cell therapies. Biological cell therapy has gained immense attention for various diseases due to unique advantages it has over chemical drugs regarding cost, ease of production, toxicity, and therapeutic efficacy. However, these cell-based therapies need an inert delivery system that can locally deliver cells and minimally elicit foreign body response. The book discusses the foreign body response to the immunomodulatory biomaterials as well as the current and future strategies for potential mitigation of considerable immune responses toward immunomodulatory biomaterials and devices.In addition, this book:<ul><li>Presents the recent developments in immunomodulatory biomaterials for cell-based therapies in various diseases</li><li>Discusses the history, advantages, and challenges of cell therapies as compared to conventional treatment</li><li>Highlights future strategies for mitigation of immune responses toward immunomodulatory biomaterials and devices</li></ul>

This book presents the recent developments in immunomodulatory biomaterials for cell-based therapies in various diseases, including diabetes, cancer, cardiovascular disease, and bone regeneration. The authors first cover the fundamentals of conventional immunology and immunomodulation, before focusing on the history, advantages, and challenges of cell therapies. Biological cell therapy has gained immense attention for various diseases due to unique advantages it has over chemical drugs regarding cost, ease of production, toxicity, and therapeutic efficacy. However, these cell-based therapies need an inert delivery system that can locally deliver cells and minimally elicit foreign body response. The book discusses the foreign body response to the immunomodulatory biomaterials as well as the current and future strategies for potential mitigation of considerable immune responses toward immunomodulatory biomaterials and devices.

Recent Advancements

Immunomodulatory Biomaterials for Cell Therapy and Tissue Engineering

&lt;p&gt;The practice of management has experienced significant changes in recent years. Advances in technology, globalization, cultural shifts, competitive pressures, and the unpredictability of a fast-paced business environment have presented new challenges as well as opportunities for today’s managers. &lt;/p&gt; 
&lt;p&gt;&lt;/p&gt; 
&lt;p&gt;&lt;em&gt;Evolution of Management Practice&lt;/em&gt; has assembled the viewpoints of leading academics, management practitioners, and business consultants in order to uncover the most effective approaches pertaining to planning, leading, organizing and controlling. The chapters delve into the challenges of digital transformations, the use of AI, sustainability issues, supply chain changes and the need for design thinking and new human resource practices. &lt;/p&gt; 
&lt;p&gt;&lt;/p&gt; 
&lt;p&gt;This book is an authoritative reference for professionals, consultants, policymakers and students and scholars of management, leadership, entrepreneurship and economics who realize that traditional management approaches need to be refined and reinvented to suit contemporary times. It will guide the practice of management for many years to come. &lt;/p&gt;

J. Mark Munoz

Evolution of Management Practice

Biomaterial Engineering

The aim of this work is as a complete reference for researchers, engineers and graduate students who are engaged in R&amp;D of biomaterials. The book facilitates the newcomers to grasp the most updated status in all the related topics in biomaterial's fields with a comprehensive, self-contained, and authoritative knowledge.
The unique feature of the book will be the combination of a collection of standard/advanced experimental protocols in preparing and fabricating biomaterials and related bioassays. This book is a step-by-step guide for newcomers, who may not be equipped with appropriate hands-on laboratory skills and experiences, to follow and repeat those important works in the field. This style is particularly important in this interdisciplinary field.
This reference work comprises 14 volumes and covers the most popular topics of biomaterials from drug delivery to gene and protein delivery, from biomedical biodetection to diagnosis, from cardiovascular diseases to tissue engineering. The content is created by the leading scientists in each field and will evolve constantly, thus it presents both high-quality and up-to-date scientific and technical information.

The aim of this work is as a complete reference for researchers, engineers and graduate students who are engaged in R&amp;D of biomaterials. The book facilitates the newcomers to grasp the most updated status in all the related topics in biomaterial’s fields with a comprehensive, self-contained, and authoritative knowledge.
The unique feature of the book will be the combination of a collection of standard/advanced experimental protocols in preparing and fabricating biomaterials and related bioassays. This book is a step-by-step guide for newcomers, who may not be equipped with appropriate hands-on laboratory skills and experiences, to follow and repeat those important works in the field. This style is particularly important in this interdisciplinary field.
This reference work comprises 14 volumes and covers the most popular topics of biomaterials from drug delivery to gene and protein delivery, from biomedical biodetection to diagnosis, from cardiovascular diseases to tissue engineering. The content is created by the leading scientists in each field and will evolve constantly, thus it presents both high-quality and up-to-date scientific and technical information.

Polymer-Drug Conjugates

Biomedical Visualization

The Trans-European Pedagogic Anatomy Research Group

International Anatomical Education

Medical Affairs’ Fundamentals: The Next Generation

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