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Leading neurologist Masud Husain shares seven fascinating and surprising cases of brain disorders from across his career - and what they can teach us about our own brains

Husain Masud: Our Brains, Our Selves / B

Our Brains, Our Selves

What a Neurologist’s Patients Taught Him About the Brain

Longlisted for the 2025 Financial Times &amp; Schroders Business Book of the Year Finalist for the National Book Critics Circle Award 2025 Shortlisted for Foyles Non Fiction Book of the Year 2025 A New York Times Bestseller An eye-opening account of the tech arms race shaping out planet, from an award-winning journalist and AI insider to the world of Sam Altman and OpenAI When longtime AI expert and journalist Karen Hao first began covering OpenAI in 2019, she thought they were the good guys. Founded as a nonprofit with safety enshrined as its core mission, it was meant, its leader Sam Altman told us, to act as a check against more purely market forces. But the core truth of this massively disruptive sector is that it requires an unprecedented amount of proprietary resources: the 'compute' power of scarce high-end chips, the sheer volume of data that needs to be amassed at scale, the humans on the ground 'cleaning it up' for sweatshop wages throughout the Global South, and a truly alarming spike in the need for energy and water underlying everything. We have entered a new, ominous age of empire with OpenAI setting a breakneck pace, as a small group of the most valuable companies in human history try to chase it down. In exhilarating prose and with unparalleled access to those closest to Sam Altman, Hao recounts the meteoric rise of OpenAI and shows us the sinister impact that this industry is having on society.

Inside the reckless race for total domination

Empire of AI

We know that we must change ourselves and the world if we want to survive. So why do we cling to old habits and false certainties instead of embracing change now? In New Beginnings, Stefan Klein delves into the most pressing problems facing our world - from the climate crisis to the rapid development of artificial intelligence - and investigates why individuals and societies often resist necessary changes, despite knowing the risks of inaction. Blending scientific insights with vivid storytelling, Klein unpacks the psychological and social forces that keep us stuck, and identifies what he calls the 'seven illusions about progress' that hinder our ability to adapt. Central to his analysis is the idea that transformation is not only necessary but also achievable, provided we understand the mechanisms of change and embrace a mindset that values adaptability. New Beginnings stands out for its ability to make complex global challenges comprehensible and relatable. With his trademark clarity and optimism, Klein inspires belief that necessary change is not only possible but accessible for a sustainable future.

Why Change Is Hard and How We Can Achieve It

New Beginnings

'Fascinating, absorbing and educative' A. C. Grayling 'Highly original and beautifully written' Dominic Lawson A compelling insight into how our imagination works, based on the latest scientific research. People often think of imagination as something used only in creative endeavours. In fact, we use imagination constantly as we reminisce, anticipate, plan, daydream, read, create imagined worlds. The truth is we live in the here and now much less than we tend to think. Imagination isn't the exception in our daily lives; it's our default setting. Yet only now are we beginning to understand exactly how it works. From hallucination to sleepwalking, from REM sleep to delusions, neurologist Adam Zeman brilliantly guides us through the latest scientific studies in the world of the imagination. He draws on research in neuroscience, the study of human origins and child development to show how the human brain is above all else a creative, imaginative organ - and that we have evolved to share what we imagine. Our brains behave in strikingly similar ways when we observe, remember, imagine or act. Imagine looking at a cube and your eye will trace the contours of the cube as if you were actually seeing it. Yet it turns out that people differ hugely in their imaginative experience. Some people lack sensory imagery altogether - they would be unable to picture their family if asked to - but still lead fulfilling, even highly creative, lives. From how we visualise to how we understand the minds of others, from the benefits of play to mental disorders, The Shape of Things Unseen dazzles and delights. It is an essential guide to the latest discoveries about the workings of the human mind.

A New Science of Imagination

The Shape of Things Unseen

'The book we need right now ... Essential reading' Professor Tom Ellis, Imperial College London 'Visionary and exhilarating ... A work of astonishing scope and imagination' Tim Coulson, author of A Little History of Everything: From the Big Bang to You 'A fascinating read ... I throroughly recommend for all audiences' Professor Mumtaz Patel, President of the Royal College of Physicians Imagine a future where we grow houses rather than build them. Where smartphones are living, clothing has opinions, and all human knowledge fits into a speck of DNA. A world where disease is a thing of the past, and the human lifespan is dramatically extended. To achieve this, says Adrian Woolfson - founder of the genome writing company Genyro - we must transform biology into a predictive, programmable engineering material. That means decoding the generative grammar of DNA: the language of life itself. It may then be possible to author genomes - and, if we choose, even rewrite our own. We are at the cusp of a technological revolution, driven by the convergence of artificial intelligence and synthetic biology. Currently at the scribbling phase - writing the genomes of viruses, bacteria and yeast - we will eventually author the genomes of extinct and never-before-realised species. Life will become computable, detached from its past, and no longer bound by Darwinian evolution. While offering extraordinary opportunities, this power also carries great risk and it is vital for everyone to understand what the future might hold. Genome writing can help preserve the planet, but may also undermine human nature and disrupt ecosystems. Bold, visionary and deeply original, On the Future of Species is an essential guide to how we should navigate this astonishing new world, offering a moral compass to help us do so safely, wisely and ethically. -- 'Explores the profound opportunities and challenges that arise when we turn evolution upside-down' John-Arne Rottingen, CEO of The Wellcome Trust 'An intriguing and disturbing analysis of a biological revolution' Robin McKie, Guardian

Authoring Life by Means of Artificial Biological Intelligence

On the Future of Species

Set in Japan, the gorgeous novel that will "break and remake your heart"

Palaver

'I thought Gavin Francis couldn't get any better, but I was wrong. This is his best and most important book' Bill Bryson 'Francis combines the precision of science with a profound insight into the human condition' GUARDIAN 'This is a book to change lives - and save them.' Ian Rankin FROM THE BESTSELLING AUTHOR OF ADVENTURES IN HUMAN BEING AND RECOVERY Between a quarter and a fifth of young people in the UK now suffer a mental disorder. One in four adults are prescribed psychiatric medication. These numbers represent a huge and recent expansion in mental health labelling, but reveal nothing of the experience of those seeking help. In The Unfragile Mind, Gavin draws on conversations with patients, colleagues, and his thirty years of practice to explore the chequered history of psychiatry, the nature of mental health and ill-health, and the problems - including mood disorders, trauma, anxiety and addiction - that he addresses daily. The mind, he argues, is dynamic and adaptive - better addressed not with rigid labels and protocols, but with curiosity, kindness, humility and hope.

Making Sense of Mental Health

The Unfragile Mind

The Sunday Times bestselling authors of The Devil You Know return with a life-affirming exploration of trauma and healing.

Stories of Survival and Transformation After Trauma – 'Profoundly moving' Siri Hustvedt

Unspeakable

'Has the power to change the way you look at the world' Steven Bartlett'The heir to Oliver Sacks' David BaddielA FINANCIAL TIMESBEST BOOK OF 2024AN INDEPENDENTBOOK OF THE MONTHGluttony. Greed. Sloth. Pride. Envy. Lust. Anger.These are the seven deadly sins, the vices of humankind that define immorality, the roots of all evil in the world. Or so some believe.But do these sins really represent moral failings, or are they simply human functions that aid us? Are they just the result of how our bodies, psyches, and brains in particular, are wired?This new book by Dr Guy Leschziner, a professor of neurology and sleep medicine, explores the underlying nature of the seven deadly sins, their neuroscientific and psychological basis, their origin in our genes and crucially how certain medical disorders give rise to them.Drawing on his clinical practice, we meet individuals whose physical and psychological conditions have given rise to these sins, where brain injury or other experiences have sparked 'immoral' actions. He explores how illness can simply expose what lies within us and investigates how the origins of these traits lie in evolutionary imperatives to preserve the wellbeing of the tribe. Perhaps, he suggests, these character traits are less of a moral question and more biological, which raises fundamental issues of responsibility and blame in the face of 'sin'.Combining cutting-edge science placed in the context of real-life experience with patients, the book reexamines where the boundaries between normal human nature, pathology and sin are drawn. And, most importantly, whether these hard-wired traits truly represent sin, or simply the intensity of our intrinsic desire to survive and thrive.

The Biology of Being Human

Seven Deadly Sins

Women Pioneers of Science

Against the Odds

'Revelatory. Covers so many topics that have been troubling me but I hadn't been able to resolve myself - as a parent and a clinician.' - CHRIS VAN TULLEKEN From autism to allergies, ADHD to long Covid, more people are being labelled with medical conditions than ever before. But can a diagnosis do us more harm than good? The boundaries between sickness and health are being redrawn. Mental health categories are shifting and expanding all the time, radically altering what we consider to be 'normal'. Genetic tests can now detect pathologies decades before people experience symptoms, and sometimes before they're even born. And increased health screening draws more and more people into believing they are unwell. An accurate diagnosis can bring greater understanding and of course improved treatment. But many diagnoses aren't as definitive as we think. And in some cases they risk turning healthy people into patients. Drawing on the stories of real people, as well as decades of clinical practice and the latest medical research, Dr Suzanne O'Sullivan overturns long held assumptions and transforms how we think about illness and health. THE MUST-READ SUNDAY TIMES BESTSELLER A BOOK OF THE YEAR IN THE TIMES, SUNDAY TIMES, FINANCIAL TIMES, GUARDIAN, ECONOMIST, OBSERVER, LONDON STANDARD, NEW STATESMAN AND IRISH TIMES AND A RADIO 4 BOOK OF THE WEEK 'A brilliant study of the dangers of overdiagnosis' - GUARDIAN 'Compassionate and bracingly independent thinking' - THE TIMES *As heard on Good Morning Britain, Sky News, Radio 4 Today and more.*

Are Medical Labels Doing Us More Harm Than Good? - THE MUST-READ SUNDAY TIMES BESTSELLER

The Age of Diagnosis

'Fascinating, insightful, lucidly and entertainingly written' A. C. GRAYLING, author of The History of Philosophy 'Extraordinary, eye-opening, startlingly original' CASS R. SUNSTEIN, co-author of Nudge 'Filled with insightful findings, this book shows that ideological extremism and polarization are not just problems to fret about but puzzles that can be studied and understood' STEVEN PINKER, author of The Better Angels of Our Nature How do our brains shape the ideologies we choose? And could our most cherished beliefs ultimately harm our brains and bodies? In The Ideological Brain, Dr Leor Zmigrod argues that when we believe passionately and extremely in an ideology, it is not only our political opinions that are changed - our entire brain can be transformed too. Drawing on cutting-edge research, Zmigrod reveals how rigid belief systems transform the way we think, act and interact with others, making us less sensitive, less adaptable and less free. Guiding you through innovative experiments, Zmigrod uncovers the deep and surprising connections between your political beliefs and the biology of your brain, exposing why some of us are more likely to gravitate towards rigid ideologies than others. She reveals the complex interplay between the psychological, neurobiological and social factors affecting our ideological choices, and carves a hopeful way forward, explaining how we can keep our minds open and free in the face of extreme ideologies. Eye-opening, provocative, and unforgettable, The Ideological Brain is a groundbreaking book that challenges you to resist black-and-white thinking and reassess your closest convictions. 'Lucid, eloquent, timely' ADAM PHILLIPS, author of Missing Out 'Deeply fascinating and beautifully written' JULIA EBNER, author of Going Dark 'One of the most brain-frying books I have read in an incredibly long time.' JOHN BURN-MURDOCH, chief data reporter, Financial Times

How Rigid Beliefs Harm Our Minds & Bodies – And Why It Matters

The Ideological Brain

Rock and Roll

Rock and Roll are very different. Rock is strong and Roll is soft. Rock hates attention. Roll loves it. But hang on . . . Maybe they have more in common than we think . . . This standout debut from Ruby Amy Thompson introduces two unforgettable characters!With bold visuals, big laughs, and a brilliantly playful layout, this is a story that celebrates connection; Rock and Roll always appear on opposite pages, yet their worlds are cleverly linked through shared experiences. Perfect for fans of The Day the Crayons Quit by Drew Daywalt and Oliver Jeffers, Odd Dog Out by Rob Biddulph, or Squirrel and Bird by Laura Baker and Stacey Thomas. This is a joyful picture book packed with read-aloud energy. A brilliant springboard for conversations about first impressions, identity, and all the weird and wonderful things that bring us together - even when we seem worlds apart.

Our Brains, Our Selves

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