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Cotton Simon: Every Molecule Matters

Every Molecule Matters

Clinical Pharmacy and Therapeutics

Structural Biology of Amyloid Fibrils is a comprehensive reference on the structure of protein aggregates in different neurodegenerative diseases and their molecular bases. Chapters describe these structures in detail, highlighting their similarities and differences across different disease states, alongside an unprecedented overview of current developments and new hypotheses emerging in amyloid fibril structure, stability and mechanisms of formation. This volume also discusses how amyloid structure may affect the ability of fibrils to spread to different sites in a prion-like manner, as well as their role in disease. Featuring chapters on NMR, X-ray crystallography, and Cryo-EM methods, and discussing the structure of amyloid fibrils obtained directly from patients, the book allows readers to understand how polymorphism is associated with disease phenotype and how fibril structure affects and influences the cellular environment. Understanding the molecular architecture of amyloid fibrils and oligomers will be an important step towards developing therapeutic interventions based on targeting the fibrils and oligomers themselves, or the processes that generate them.

Structural Biology of Amyloid Fibrils

This book emphasizes how new generation materials discovered recently (like graphene and topological insulators) can be understood using simple Quantum Transport Theory. The book could also be used as a text in Advanced Solid State/Condensed Matter Courses in Physics or Chemistry and in branches of Engineering.

Quantum Transport in Dirac Materials

Plant Proteins: Farm to Table addresses all aspects of plant proteins, including plant science, chemistry, processing, formulations, nutrition, and trends. This important reference also covers cereal and pulse plant-based and soy proteins and presents protein extraction and processing techniques, as well as ingredient principles and their application in formulating plant-based products, from ingredient interactions to processing to measurement science, including sensory. The book addresses not only the different types of plant proteins and their nutritional aspects but also plant protein processing and ingredients and formulating plant proteins to develop plant-based foods. It will be a welcomed addition to the libraries of food technologists, research scientists, product developers, process engineers, students and educators.

Farm to Table

Plant Proteins

Plant Biology, sustainability and climate change

Radiation Spectrum and Plant Metabolism: Interaction from the Sub-cellular to Ecosystem Level offers a clear illustration of the interaction between radiation spectrums and the dynamics of biological systems in plants. Explaining the light-Phyllosphere relationship, this volume describes metabolite chemistry, thus reflecting the developmental and functional fitness of the plant. As climate change has resulted in a natural variation in the cosmic radiation spectrum, a knowledge gap has emerged about the changing radiation spectrum and its impacts on plant metabolism. This book addresses the subject in-depth, providing insights into the functional role of photoreceptors, pigments, and various metabolites in coping with this alteration. It will be a valuable reference for photo biologists, biophysicists, and biochemists for deciphering the impacts of radiation spectrum on plant metabolism. Researchers working in the field of metabolite chemistry and metabolomics will also find it useful to comprehend the physical laws governing the interaction of radiation spectrum with biological system.

Interaction of Radiation Spectrum with Sub Cellular Ecosystem Level

Radiation Spectrum and Plant Metabolism

This book will not only deal with the analysis of nutraceuticals, but will also focus on the extraction and purification of the analytes using newer tools/instruments. It will also help the analyst during the actual estimation of these compounds from different matrices.

Practical Guide to LC Analysis of Nutraceuticals

Supercritical Fluid Science and Technology

From Basic Principles to Industrial Applications

Supercritical CO2 Extraction

Foundations and Frontiers in Enzymology

Sustainable Process Intensification for Biocatalysis: Applications in Enzymology and Biotechnology, a new volume in the Foundations and Frontiers of Enzymology series, offers applied instruction in process intensification principles for applications in enzymology and biotechnology, helping researchers and practitioners implement these techniques across various uses and industries, from healthcare to food and biofuel. Leaders in the field discuss a full range of approaches and enabling technologies, from microwave to ultrasound, hydrodynamic cavitation, and combination chemical and biological catalysis techniques, such as multiphase reactors, microreactors, scale-bioprocesses, and enzyme cascades. Later chapters examine ongoing advances and their implementation across different industries, including pharmaceuticals, perfumes, polymers, and agrochemicals, with a final chapter discussing next steps in research and future directions. Throughout the book, and across applied examples, emphasis is placed on driving sustainable research approaches and manufacturing.

Applications in Enzymology and Biotechnology

Sustainable Process Intensification for Biocatalysis

Functional Foods and Nutraceuticals

Seaweeds are a rich source of number of metabolites such as polyphenols, polysaccharides, fatty acids, proteins, peptides, which can be used as functional ingredients in many industrial applications such as functional food, nutraceuticals, pharmaceuticals and cosmeceuticals. While chromatographic and spectroscopic techniques have made bioactives analysis easier than before, their successful analysis depends on extraction techniques used. The book covers various emerging technologies for the extraction and characterization of bioactive compounds from seaweeds. The book provides in-depth information about the technique, its benefits and disadvantages, and potential industrial applications.

Extraction and Characterization Techniques

Seaweed Bioactives

De Gruyter Textbook

This book gives a concise introduction to the nature, structure, and reactivity of organic compounds. The author introduces complex concepts in an accessible manner. By covering everything from functional groups and spectroscopy to molecular orbital theory and reaction mechanisms, this book gives the reader a true insight into organic chemistry without going into gratuitous amounts of detail.

Organic Reactivity and Reactions

Introductory Organic Chemistry

Pharmaceutical QbD with Design of Experiments: Statistical Tools and Applications in Drug Delivery Systems offers comprehensive coverage of best practices in pharmaceutical manufacturing. The first section discusses the principles and basics of Quality by Design (QbD). Part two covers the foundational statistical principles and tools for the Design of Experiments (DoE). Section three is dedicated to the applications of QbD for conventional formulations. The next section provides ample coverage of applications to Novel Drug Delivery Systems (NDDS), including micro and nano-particles. The final section discusses the application of QbD for the optimization of pharmaceutical processes and equipment. Researchers in pharmaceutical manufacturing will benefit from this thorough statistical review, while students in this field will gain practical insights the experienced chapter authors provide in case studies. Industry professionals can find solutions to their particular problems within the insights and strategies shared in this book.

Statistical Tools and Applications in Drug Delivery Systems

Pharmaceutical QbD with Design of Experiments

Series in Computational Biophysics

Multiscale methods are ideally suited to simulate the processes at work in many biomolecular systems, which often span a large range of time and length scales. Multiscale Methods in Molecular Biophysics highlights the advantages of these methods for integrating different levels of detail in a single simulation setting. It covers the practical methodology and successful applications in areas such as enzyme catalysis, protein folding, and ligand binding. The book is divided into three main sections: combination quantum and classical (atomistic) descriptions, approaches that combine atomistic and coarse-grained level of details, and multiscale methods where the resolution coupling is between global collective coordinates and local details.

Multiscale Methods in Molecular Biophysics

Every Molecule Matters

Informations bibliographiques

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