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Diseases of Swine

List of Contributors xi Editors' Note xxiii Acknowledgments xxv Section I Veterinary Practice 1 1 Evidence-based Practice of Swine Medicine 3 Evidence-based medicine, determining causation, impact of pig flow, synthesizing evidence for a diagnosis, conducting a field investigation, case management, 5 circles, client communication. 2 The Healthy Pig 29 Reference intervals, health pig parameters, reference population, swine health, physiologic parameters. 3 Behavior and Welfare 49 Definitions of welfare, normal vs abnormal behaviors, maternal behaviors, minimizing welfare impact of invasive procedures, feeding and drinking behaviors, human interactions, behavior responses due to disease, recognizing pain. 4 Effect of Genetics on Health 75 Genetic selection, heritability, resistance, phenotype, gene, trait. 5 Facilities and Environment 83 Effect of the environment on health, thermal conditions, air quality, disease transmission via ventilation, facility design for bioexclusion, filtration, technology for health monitoring. 6 Effect of Nutrition on Health 97 Nutrient requirements, body condition, energy requirements, vitamins, feeding programs, weaning transition, water quality, alternative feedstuffs, feedstuff processing, alternative feed programs. 7 Tools and Techniques of Practice 111 Common antemortem and postmortem sampling techniques including necropsy, cerebrospinal fluid collection, joint sampling, processing fluids, urine collection, feed sampling. 8 Overview of the Diagnostic Process, Diagnostic Tests, and Interpretation 129 How diagnostic tests are performed, advantages, and disadvantages; PCR testing considerations including quantitative interpretation; appropriate uses of genetic sequencing; sources of variation in test results, screening versus confirmatory tests, test cutoff values, appropriate applications of advanced sequencing technologies. 9 Infectious Disease Surveillance in Swine Populations 151 Designing a surveillance program, sample selection, assay selection, sampling strategies, using data to detect changes. 10 Biosecurity, Disease Control, and Elimination 169 Principles of biosecurity, outbreak investigation, hierarchy of control measures, specific interventions for farm exposures, disease elimination strategies, derivation of negative populations. 11 Anesthesia and Surgical Procedures in Swine 189 Catheterization techniques, IV fluid therapy, epidural injection, anesthetic drug combinations, and reversal agents; surgical procedures including castration, correction of prolapses, cystostomy procedures, cesarean section, fracture repair, tusk removal, abdominal and musculoskeletal procedures. 12 Drug Pharmacology and Treatment Management 215 Considerations for treatment, swine specific pharmacokinetics, residue avoidance, withdrawal management, establishing treatment regimens, impact of drug treatment on immunity, anti-inflammatory drugs, antimicrobial stewardship, drug toxicities, interpreting in vitro SIR interpretations, clinical parameters suggesting efficacy, pig treatment implications of antibiotic resistance. 13 Veterinarian, Consumer, and Public Health 239 Safety, foodborne illness, physical hazards, antimicrobial resistance, chemical hazards, agrotourism. Section II Body Systems 253 14 Cardiovascular and Hematopoietic Systems 255 Anatomy, pathophysiology, mulberry heart disease, anemia, shock, clinical pathology. 15 Digestive System 273 Interactions of microbiota, nutrition, immune system; anatomy, pathophysiology, gastric ulcers, hemorrhagic bowel syndrome, prolapses, hernias. 16 Immune System 303 Innate and adaptive immunity; cellular, humoral, mucosal and passive immune mechanisms, stress, nutrition, immunosuppression, vaccination; lactogenic immunity (humoral and CMI). 17 Integumentary System-Skin, Hoof, and Claw 329 Pathophysiology of skin, infectious conditions and non-infectious conditions; ear necrosis, porcine dermatopathy and nephropathy syndrome; pathophysiology of coronary band, foot and claw; traumatic and nutritional contributors to foot and claw lesions. 18 Mammary System 351 Structure and development, physiology of lactation, physiology of maternal immunity, pathophysiology of lactation dysfunction, mastitis, dysgalactia, risk factors. 19 Nervous and Locomotor System 375 Pathophysiology of nervous and musculoskeletal systems, muscle, bone, joint and eye; congenital abnormalities, splayleg, congenital tremor, myopathy, porcine stress syndrome, arthritis, metabolic bone disease, rickets, osteochondrosis. 20 Reproductive System 417 Control of estrus, pregnancy, and parturition; pregnancy diagnosis, dystocia, prolapse, discharge, male reproductive function and semen quality; laboratory investigation of abortion and reproductive failure. 21 Respiratory System 439 Anatomy, structure, function; nasopharynx (including tonsil) and commonly found common microbiota, pathophysiology. 22 Urinary System 457 Anatomy, structure, function; pathophysiology of infectious and noninfectious conditions. Section III Viral Diseases 479 23 Overview of Viruses 481 General characteristics of viruses, virus taxonomy, detection and characterization of viruses. 24 African Swine Fever Virus 499 African swine fever, African swine fever virus, viral hemorrhagic fever, domestic pigs, wild suids, pandemic, vaccine. 25 Astroviruses 513 Porcine astrovirus, mamastrovirus, swine, diarrhea, meningoencephalomyelitis, paralysis. 26 Caliciviruses 517 Vesicular exanthema of swine virus, porcine noroviruses, porcine sapoviruses, St-Valérien virus. 27 Circoviruses 527 Porcine circoviruses, PCV1, PCV2, PCV3, PCV4, postweaning, reproductive, porcine dermatitis and nephropathy syndrome, PCV2 vaccines. 28 Coronaviruses 547 Transmissible gastroenteritis virus, porcine respiratory coronavirus, porcine hemagglutinating encephalomyelitis virus, porcine epidemic diarrhea virus, porcine deltacoronavirus, swine acute diarrhea syndrome coronavirus. 29 Filoviruses 589 Orthoebolavirus, Reston virus (RESTV), Ebola virus (EBOV). 30 Japanese Encephalitis Virus and Other Orthoflaviviruses 597 Japanese encephalitis virus, Murray Valley encephalitis virus, West Nile virus, others. 31 Herpesviruses 615 Pseudorabies virus (suid alphaherpesvirus 1, Aujeszky's disease virus), porcine cytomegalovirus (suid betaherpesvirus 2), porcine lymphotropic herpesviruses 1-3 (suid gammaherpesviruses 3-5), malignant catarrhal fever virus (ovine gammaherpesvirus 2). 32 Influenza Viruses 645 Influenza A virus, swine, epidemiology, pathogenesis, diagnosis, vaccines. 33 Paramyxoviruses 665 La Piedad-Michoacan virus (blue eye paramyxovirus), Menangle virus, Nipah virus, porcine parainfluenza virus 1. 34 Parvoviruses 685 Porcine parvoviruses, porcine bocaviruses, canine parvovirus 2. 35 Pestiviruses 699 Classical swine fever virus, Bungowannah virus, bovine viral diarrhea virus, Border disease virus, atypical porcine pestivirus. 36 Picornaviruses 723 Foot-and-mouth disease virus, swine vesicular disease virus, encephalomyocarditis virus, porcine teschovirus, Seneca Valley virus, porcine kobuvirus, porcine sapelovirus, porcine enterovirus G, swine pasiviruses, porcine tottorivirus, parechovirus A. 37 Porcine Reproductive and Respiratory Syndrome Virus (Porcine Arteriviruses) 769 Betaarterivirus, PRRS, PRRSV, acute infection, persistent infection, reproductive disorder, respiratory disease, immune suppression, vaccination, CD163, genetic resistance and resilience. 38 Rotaviruses and Reoviruses 797 Porcine rotaviruses, rotavirus A, rotavirus B, rotavirus C, rotavirus H, porcine reoviruses, mammalian reoviruses. 39 Rhabdoviruses 813 Rabies virus, vesicular stomatitis viruses. 40 Swinepox Virus 823 Swinepox, swinepox virus, SWPV. 41 Miscellaneous Viral Infections 831 Porcine adenoviruses, anelloviruses, torque teno sus viruses, bunyaviruses, hepatitis E virus, porcine endogenous retroviruses, togaviruses, eastern equine encephalitis virus, getah virus, Sagiyama virus, Ross River virus, porcine torovirus. Section IV Bacterial Diseases 849 42 Overview of Bacteria and Microbiota 851 Characteristics of genera, disease mechanisms, table of bacterial diseases, issues in the development of bacterial disease (normal microbiota, biofilms, dysbacteriosis), and understanding microbial census data. 43 Actinobacillus spp. 857 Actinobacillus pleuropneumoniae - pleuropneumonia; Actinobacillus suis - septicemia, pleuropneumonia; Actinobacillus equuli - septicemia. 44 Bordetella 879 Bordetella bronchiseptica - non-progressive atrophic rhinitis, bronchopneumonia. 45 Brachyspira spp. 891 Brachyspira hyodysenteriae, hampsonii, suanatina - swine dysentery, Brachyspira pilosicoli - intestinal (colonic) spirochetosis, Brachyspira intermedia, murdochii - occasional colitis. 46 Brucella 913 Brucella suis - infertility, abortion, perinatal mortality. 47 Clostridia 929 Clostridium perfringens type C - necrohemorrhagic enteritis, Clostridium perfringens type A - enteritis, Clostridioides difficile - necrotizing colitis, Clostridium septicum, perfringens type A, novyi, chauvoei - cellulitis and gas gangrene, Clostridiium tetani - tetanus, Clostridiium botulinum - botulism. 48 Erysipelothrix spp. 947 Erysipelothrix rhusiopathiae, tonsillarum - septicemia, arthritis, endocarditis. 49 Escherichia 957 Neonatal E. coli diarrhea, postweaning E. coli diarrhea infections and edema disease, E. coli causing fatal shock, systemic E. coli infections, coliform mastitis, nonspecific urinary tract infections. 50 Glaesserella 997 Glaesserella parasuis - fibrinous polyserositis and arthritis. 51 Lawsonia 1009 Lawsonia intracellularis - porcine proliferative enteropathy, proliferative hemorrhagic enteropathy. 52 Leptospira 1023 Leptospira spp. serovars Pomona, Kennewicki, Bratislava, Muenchen, Tarassovi, Canicola, Grippotyphosa, Hardjo, others - abortion and stillbirths. 53 Mycoplasmataceae 1035 Mycoplasma hyopneumoniae - pneumonia; Mycoplasma hyorhinis - polyserositis, arthritis; Mycoplasma hyosynoviae - arthritis; Mycoplasma (Eperythrozoon) suis - anemia; other mycoplasmas - mostly non-pathogenic. 54 Pasteurella 1057 Pasteurella multocida - progressive atrophic rhinitis, pneumonia, septicemia. 55 Salmonella 1073 Salmonella Choleraesuis var. kunzendorf - septicemia, enterocolitis; Salmonella Typhimurium, Heidelberg, Typhisuis - enterocolitis; Salmonella Dublin, Enteriditis - meningitis. 56 Staphylococcus spp. 1089 Staphylococcus hyicus - exudative epidermitis; Staphyloccocus aureus - skin infections, mastitis, others. 57 Streptococcus spp. 1097 Streptococcus suis - septicemia, meningitis, others; Streptococcus porcinus - cervical lymphadenitis; Streptococcus dysgalactiae subsp. equisimilis - arthritis; Other streptococci - various conditions. 58 Miscellaneous Bacterial Infections 1119 Actinobaculum (Eubacterium) suis - cystitis, pyelonephritis; Bacillus anthracis - anthrax; Burkholderia pseudomallei - melioidosis; Campylobacter spp. - subclinical shedding; Chlamydia spp. - enteritis, conjunctivitis, pneumonia, abortion, etc.; Enterococcus durans and hirae - diarrhea; Klebsiella pneumoniae - septicemia; Listeria monocytogenes - septicemia, encephalitis, abortion; Mycobacterium spp. - tuberculosis; Rhodococcus equi - granulomatous lymphadenitis; Treponema pedis - ear necrosis, other skin lesions; Trueperella spp. - abortion, abscesses, pyogenic sepsis; Yersinia spp. - enterocolitis. Section V Parasitic Diseases 1149 59 External Parasites 1151 Mange (Sarcoptes, Demodex), lice, fleas, mosquitoes, flies (myiasis), ticks. 60 Coccidia and Other Protozoa 1161 Coccidia (Cystoisospora, Eimeria), Toxoplasma, Sarcocystis, Cryptosporidium, Giardia, Balantidium coli, Entamoeba. 61 Internal Parasites: Helminths 1179 Nematodes - Gongylonema, Hyostrongylus, Strongyloides, Ascaris, Trichinella, Trichuris, Oesophagostomum, Metastrongylus, Paragonimus, Stephanurus and others; Cestodes - Echinococcus, Taenia, and others; parasiticides. Section VI Non-Infectious Diseases 1193 62 Nutrient Deficiencies and Excesses 1195 Factors contributing to nutritional diseases; nutrient deficiencies and excesses; clinical signs and diagnostic investigation process. 63 Mycotoxins in Grains and Feeds 1215 Aflatoxin, ochratoxin, citrinin, trichothecenes (T2 toxin, DON), zearalenone, and fumonisins. 64 Toxic Minerals, Chemicals, Plants, and Gases 1235 Minerals, feed additives, pesticides, toxic plants, gases; effects of water quality; toxic gases and ventilation failure. Index 1257

Veterinary Forensic Sciences and Medicine covers all relevant aspects in a succinct, easy-to-read, comprehensive format intended to be taught in a single semester course, including the application of veterinary forensic medicine to cases. Most importantly, the book covers both the scientific and legal principles for veterinary f

Veterinary Forensic Medicine and Forensic Sciences

Essentials in Animal Law and Welfare

This textbook distills the various aspects of international farm animal, wildlife conservation, food safety and environmental protection law in an accessible way for an audience of practitioners, scholars and graduate students.

International Perspectives on Sustainable Agriculture and Wildlife Regulation

Farm Animal Welfare Law

Ever since its establishment by USDA regulation in the mid-1980s, the Institutional Animal Care and Use Committee (IACUC) has evolved as the premier instrument of animal welfare oversight within research institutions in the United States. As biomedical research continuously grows, the role and impact of the IACUC has increased in scope and complexity. The IACUC Handbook has become an invaluable resource for individuals when the time comes for them to serve on their institution's IACUC. It provides a foundation for understanding and implementing the many and varied responsibilities of this committee.This fourth edition comprehensively addresses the significant changes in the pertinent regulatory environment and interpretation of applicable federal laws, regulations, and policies. It includes regulatory updates, as well as best practices, and new chapters on basic IACUC operations; animals used in agricultural research and teaching; invertebrates; pandemic and disaster planning; the Pacific Rim ethical review framework; operational communications and workflow; reduction of regulatory burden; and research reproducibility and role of the IACUC. It also adds new authors and editors widely respected in the field. An essential resource for IACUC members, university administrators and compliance personnel, laboratory animal veterinarians, and scientific investigators whose work involves animal research, this new edition ensures the book's continued acceptance as the standard reference in the field.Chapter 39 of this book is freely available as a downloadable Open Access PDF at http://www.taylorfrancis.com under a Creative Commons (CC-BY) 4.0 license.

The IACUC Handbook

Farm-poultry Doctor. Prevention and Cure of Poultry Diseases

A practical, image-driven guide to assessing tumors in canine and feline patients The newly revised second edition of Atlas for the Diagnosis of Tumors in Dogs and Cats delivers an authoritative and practical visual guide to common veterinary tumors. A convenient desk reference, this book helps vets quickly and accurately assess tumors when they present. It focuses on relevant clinical details that aid in rapidly developing an effective treatment plan and prognosis. Atlas for the Diagnosis of Tumors in Dogs and Cats is organized by body system, with each tumor type including paired histological and cytologic images. The latest edition also offers a new chapter on special diagnostic tests, like new imaging modalities, immunohistiochemistry, and molecular diagnostics. Readers will also find: <ul><li>A thorough introduction to grading and staging tumors</li><li>Comprehensive explorations of selected lesions of the head and neck</li><li>Practical discussions of special diagnostic tests</li><li>Complete treatments of sample handling, including cytologic specimens and biopsy specimens</li></ul> Atlas for the Diagnosis of Tumors in Dogs and Cats is an essential patient-side resource for any veterinarian or specialist involved in the diagnosis of tumors, as well as for veterinary students and interns and residents in pathology, dermatology, internal medicine, surgery, and oncology.

Atlas for the Diagnosis of Tumors in Dogs and Cats

Jubb, Kennedy, and Palmer's Pathology of Domestic Animals: Volume 3

The 3rd edition of your #1 go-to resource for veterinary critical care, Small Animal Critical Care Medicine, has been significantly updated to focus specifically on diagnostic and management strategies for the sickest veterinary patients. It covers critical care medical therapy, monitoring, and prognosis - from assessment and stabilization through the entire course of intensive care treatment. To make therapeutic decisions easier, clear and practical guidelines address underlying clinical findings, pathophysiology, outpatient follow-up, and long-term care. Editors Deborah Silverstein and Kate Hopper, along with leading experts from the veterinary emergency and critical care profession, have created this indispensable resource to help you and your team provide the highest standard of care for your critically ill patients.<ul><li>Over 200 concise, thoroughly updated chapters cover all the clinical areas needed for evaluating, diagnosing, managing, and monitoring a critical veterinary patient</li><li>More than 150 recognized experts and many new authors offer in-depth, authoritative guidance on emergency and critical care clinical situations from a variety of perspectives</li><li>A problem-based approach focuses on clinically relevant details</li><li>Hundreds of full-color illustrations with updated photos and videos depict various emergency procedures, such as chest tube placement</li><li>Handy appendices offer quick access to the most often needed calculations, conversion tables, continuous rate infusion determinations, reference ranges, and more</li><li>Practical, user-friendly format makes reference quick and easy with summary tables, boxes highlighting key points, illustrations, and algorithmic approaches to diagnosis and management</li></ul><ul><li>NEW! Coverage of high-flow nasal oxygen therapy and both core and advanced concepts for mechanical ventilation helps you deliver high-quality care to patients with respiratory failure</li><li>NEW! Chapters on current critical care topics include Assessment of Intravascular Volume, Urine Osmolality and Electrolytes, and Infectious Disease Control in the ICU</li><li>NEW! Chapters on novel procedures offer coverage of tracheal stents, urinary diversion techniques, and an in-depth review of point-of-care ultrasound with extensive figures and images</li><li>NEW! Coverage of increasingly prevalent problems seen in the intensive care unit includes coagulation disorders of the critically ill patient, feline aortic thromboembolism, oxygen toxicity, and treatment of severe hypertension</li><li>NEW! Chapters on shock fluid therapy and transfusion therapy provide cutting edge information on how to prevent complications and maximize resources</li><li>NEW! Prevention of Compassion Fatigue and Burnout chapter addresses this major challenge currently affecting the veterinary profession</li><li>NEW! Algorithms and figures throughout the text clarify key concepts and aid in diagnosis and treatment</li><li>NEW! Enhanced eBook, included with the purchase of a new print copy of the book, provides online access to a fully searchable version of the text and makes its content available on various devices</li><li>UPDATED! Coagulation section includes chapters on hemostasis, management of the bleeding patient, coagulation and platelet monitoring, and viscoelastic monitoring</li><li>EXPANDED! Pharmacology section offers coverage of cannabis, trazadone, gabapentin, pimobendane, and appetite stimulants</li></ul>

Small Animal Critical Care Medicine

Evocative, funny and poignant, this is the third volume of memoirs from James Herriot who inspired the television series All Creatures Great and Small

All Things Wise and Wonderful

Drawing on research into how dogs naturally rear their young, and how dogs have evolved to behave and spend their time, How to Raise a Puppy supports a new way of sharing our lives with our dogs.

A Dog-centric Approach

How to Raise a Puppy

Fractures in the Horse ist ein umfassendes zeitgemäßes Referenzwerk zu Frakturen beim Pferd.

In den ersten 15 Kapiteln werden Grundlagen behandelt wie:
* Struktur und Funktion der Knochen, physiologische Aspekte der Anpassung, Stressschutz und ultrastrukturelle Morphologie
* Die Pathophysiologie von Knochenbrüchen, insbesondere die wesentlichen Merkmale von Knochenversagen, verschiedene Brucharten, Belastungsmerkmale, Spannung und Dehnung.
* Die Epidemiologie von Frakturen mit geographischer, disziplinärer und pferdespezifischer Inzidenz, Risikofaktoren und Varianten sowie Vorhersagbarkeit.
* Bildgebende diagnostische Verfahren wie Röntgen, Ultraschall, Szintigraphie, Magnetresonanztomographie, Computertomographie und Positronenemissionstomographie.
* Behandlung akuter Frakturen, präoperative Planung, Anästhesie und Analgesie, Versorgung von stehenden Frakturen und Umgang mit Komplikationen.
* Chirurgische Ausrüstung und Reparaturtechniken, externe Koaptation und Rehabilitation.

In den 22 weiteren Kapiteln werden sämtliche klinisch relevanten Frakturen behandelt. Beschrieben werden jeweils die relevante Anatomie, die Frakturtypen, Inzidenz und Ursachen, klinische Merkmale und Erscheinungsformen, Bildgebung und Diagnose, Behandlung akuter Frakturen sowie Behandlungsoptionen und -techniken. Zudem enthalten die Kapitel eine Dokumentation der verfügbaren Ergebnisse sowie durchgängig Empfehlungen des Autors.

Fractures in the Horse ist ein aktuelles Referenzwerk für alle, die sich mit Pferdemedizin beschäftigen. Es ist als Handbuch für Chirurgen, Diagnostiker, Assistenzärzte und Ärzte in Ausbildung geeignet. Tierärzten dient es als Nachschlagewerk für die Behandlung von Frakturen und vermuteten Frakturen in der Praxis, bei der Beratung der Tierhalter und der Entscheidungsfindung. Einzelne Kapitel sind auch für Anästhesisten, Chirurgen und klinisches Personal, das für die bildgebende Diagnostik zuständig ist, von Interesse.

Fractures in the Horse

Poultry Diseases, Causes, Symptoms and Treatment, With Notes On Post-Mortem Examinations

Jean-Marie Denoix is the world's leading equine musculoskesletal system anatomist and has become one of the foremost equine diagnostic ultrasonographers. There is therefore nobody better to compile a reference atlas of the clinical anatomy of the foot, pastern and fetlock, correlated with images obtained by radiography, diagnostic ultrasonography and magnetic resonance imaging. Advanced imaging techniques require in-depth knowledge of anatomy for accurate interpretation and, especially when using magnetic resonance imaging, this must be a three-dimensional concept of anatomy.This new edition replaces ultrasound images and most of the radiographic and MRI images with new, updated versions and adds brand new images of extraordinarily high quality. The multiple views of each area of the distal limb provide an extremely detailed evaluation, while every part opens with an anatomical drawing by the author. Each double-page spread deals with a single dissection viewed by means of colour photographs, labelled B&amp;W equivalents, plus x-rays, ultrasound and MRI scans as required.Diagnosis and management of distal limb lameness require a precise knowledge of the functional anatomy and biomechanics of the equine distal joints, ligaments and tendons, presented in the last chapter. The atlas is designed for maximum clarity using a generous page size and is essential for anybody involved in detailed anatomical study, complex lameness evaluation or advanced imaging techniques.

An Atlas of Clinical Anatomy and Comparative Imaging

The Equine Distal Limb

Diseases of Swine

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