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Kaneko Kunihiko: Universal Biology

Universal Biology

The Physics of Life through the Macro-Micro Consistency Principle

Molecular Mediators in Health and Disease: How Cells Communicate

From Discovery to Function in Health and Disease

PACAP

A leading scientist’s guide to the way our immune system protects us—but only most of the time &nbsp; What is our immune system, and how does it work? A vast array of cells, proteins and chemicals spring into action whenever our bodies are damaged, but immunity is not something you can see, touch, or feel. It can fight off malicious bacteria and viruses, locate cancerous growths, and even rewire our brains—but sometimes our own tissues can get caught in its crossfire, with catastrophic consequences. &nbsp; Humans may be the most disease-ridden animals on the planet. John Trowsdale shows how the immune system protects us, and how our bodies invest huge resources to keep it running. Immunity influences how we age and controls how we learn to fight off recurring diseases, and how our bodies respond to chronic conditions such as heart disease and dementia. But, in the case of allergies and autoimmune conditions, it can also easily get things wrong. &nbsp; What the Body Knows is a hugely readable account of a fascinating phenomenon—one which, for good or for ill, impacts every aspect of our lives.

A Guide to the New Science of Our Immune System

What the Body Knows

Harnessing Quorum Quenching for Disease Management

Foundations and Frontiers in Enzymology

Protein Dynamics: Experimental and Computational Approaches investigates protein biology from a biophysical standpoint. The book covers a wide range of topics including functional protein dynamics, intrinsically disordered proteins, protein folding, misfolding and aggregation, and membrane protein-protein communication. Protein allosteric conformational changes caused by drug binding and disease-associated mutations is also featured, alongside protein dynamics in the context of computer-based drug design. Biophysical techniques for investigating protein structure-dynamics-function relationships across these topics are explored, considering the latest experimental and computational approaches in the field. This book is an ideal reference for researchers in working in biophysics, biochemistry, and related areas.

Experimental and Computational Approaches

Protein Dynamics

Methods in Signal Transduction Series

This volume will describe a variety of methodologies employed for the study of epithelial cells. These methods include isolating primary cells and generate and maintain organoid cultures; culturing intestinal and renal epithelial cell lines; characterizing epithelial cell polarity and differentiation; and others.

This volume will describe a variety of methodologies employed for the study of epithelial cells. These methods include isolating primary cells and generate and maintain organoid cultures; culturing intestinal and renal epithelial cell lines; characterizing epithelial cell polarity and differentiation; and others.

Epithelial Cell Interactions

Methods in Enzymology

RNA Enzymology and Technology: Volume 726

Biophysics of Tissue Self-Organization in Morphogenesis: The Role of Dynamics Along the Biointerface delves into the interactions between tissue and the extracellular matrix. It explores the fundamentals of cell self-rearrangement and the interrelation between biological mechanisms and physical principles responsible for tissue self-organization. The book examines modeling approaches to tissue self-organization and the application of engineering principles to solve medical problems. It also discusses tools, applications, and medical implications, particularly in embryo development, wound healing, and cancerous diseases, concluding with future developments. Covering subcellular to supracellular levels, this book is an interdisciplinary guide for researchers in cell biology, biophysics, developmental biology, and more.

The Role of Dynamics Along the Biointerface

Biophysics of Tissue Self-Organization in Morphogenesis

A Computational Approach

Modeling Structure-Function Relations in Ion Channels

Stem Cell-Mediated Regulation of Pyroptosis investigates the role of pyroptosis in various types of stem cells and stem cell-derived exosomes, considering how they can accelerate tissue repair and regeneration in inflammatory diseases. The book begins with an introduction to the mechanisms of pyroptosis and methods available for its detection. It then considers pyroptosis and its relationship to stem cells, before delving into this interaction across various conditions ranging from cerebral injury, spinal injury and cardiac injury to osteoarthritis, cancer, and many more. This book delves into the latest research findings and future directions in the study of stem cells and pyroptosis, enabling readers to understand the cellular mechanisms underlying this form of cell death and the clinical significance of stem cells in the context of pyroptosis-induced diseases. It considers therapeutic implications and potential strategies targeting this pathway for the treatment of such conditions, providing a comprehensive reference that will be useful to researchers working across cell biology, regenerative medicine, immunology, therapeutics and other related fields.

Stem Cell-Mediated Regulation of Pyroptosis

This textbook introduces biology as an interdisciplinary science, linking physics and chemistry to biological processes that operate within the laws of thermodynamics. Based on an evolutionary narrative, the focus is on the molecular composition and the biochemistry of cells. By grounding biology in its molecular foundations, this approach reveals unifying principles underlying life's diversity and provides a conceptual framework for biological complexity. Core concepts include macromolecular structure and function, information encoding and decoding, and universal principles of energy conversion.Key Features<ul> <li>Reflects a novel biology teaching approach </li> <li>Uses evolution as the unifying framework</li> <li>Introduces a narrative towards complexity in life</li> <li>Bridges chemistry and physics to make molecular biology accessible</li> <li>Focuses on bacteria and archaea as the simplest life forms to illustrate fundamental principles</li> <li>Progresses from molecules through molecular interactions to cellular processes </li> <li>Highlights key biological concepts with summaries and reflective questions </li> </ul>This textbook is designed for students seeking an integrated introduction to biology that connects molecular mechanisms to cellular structures.

Fundamentals of Biology 1

From Molecules to the Biochemistry of Cells

A Practical Introduction

Membrane Protein Bioinformatics

Cold-Adapted Enzymes: Biochemistry and Biotechnology provides a detailed investigation into enzymes that adapt to cold environments. It covers the catalytic, structural and regulatory properties of this type of enzyme and the potential advances in their biotechnological applications.Topics covered include the evolution of enzymes in cold environments, enzymes involved in carbohydrate metabolism (such as xylanases, B-galactosidase, and B-glucosidase), cold-adapted enzymes in lipid metabolism (such as esterases and lipases) and redox enzymes. The book also explores bacterial cold-adapted enzymes and those from organisms which live in extreme environments like Antarctica. Recombinant expression methods, protein engineering and computational approaches are also featured. This book offers a complete overview of cold-adapted enzymes and is the latest volume in the Foundations and Frontiers of Enzymology series. This is a useful reference for researchers across a range of interdisciplinary fields including biochemistry, enzymology, biotechnology, molecular evolution, structural biology and microbiology.

Biochemistry and Biotechnology

Cold-Adapted Enzymes

Universal Biology

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