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Sodickson D: The Future of Seeing

The Future of Seeing

How Imaging Is Changing Our World

Debating the use of genomic tools and their societal impactOver the past decade, the field of human genetics has produced an extraordinary range of discoveries-including the refinement of polygenic scores, which use a person's DNA to estimate their likelihood of developing a trait or disease. But are these new technologies ready to leave the research lab and be deployed in schools, fertility clinics, and the wider world? In What We Inherit, Sam Trejo and Daphne Martschenko offer different perspectives on the societal impact of the rapidly unfolding DNA revolution. Trejo, a sociologist and expert on the complex ways people's genes influence their life's trajectory, believes that new genomic tools-if used thoughtfully-can improve society; Martschenko, a bioethicist who specializes in the thorny social issues raised by biomedical advances, is more cautious. They debate both the risks and the opportunities posed by such new technologies as at-home genetic tests and polygenic embryo selection-all while engaging in a wide-ranging dialogue on ideology, biology, and social inequality. While grappling with these new technologies, Trejo and Martschenko remind us that we inherited from our ancestors not only DNA but also wrong-headed ideas about genes. Together, they caution against two particularly harmful genetic myths: that genes determine an individual's future, and that race and genetics are inherently connected. A polygenic score, for example, is not a definitive marker for disease. And race is a sociopolitical construct, not a biological identity. Trejo and Martschenko argue that, to avoid exacerbating social inequality, we need to begin regulating genomic tools sooner rather than later.

How New Technologies and Old Myths Are Shaping Our Genomic Future

What We Inherit

Concepts in Reproduction integrates the principal mechanisms of reproduction among eukaryotes, with a focus on animals and plants. The text emphasizes processes and approaches that evolved to address specific problems inherent in reproduction using examples from morphology, functional studies, and genetic studies. The many high-quality figures complement the text and provide visual storyboards. Footnotes and boxes are used throughout to provide depth and to enrich understanding. Information is compartmentalized to guide new readers through complex material while offering in-depth coverage of significant and impactful topics for experts.Key Features¿ Accessibility for a broad audience, using figures that complement the text to explain key concepts and mechanisms ¿ Integrative presentation that emphasizes the science behind the story¿ Breadth of coverage to promote comparative thought¿ Rich multiple-choice questions that span the contentConcepts in Reproduction is recommended for advanced undergraduate students, new graduate students, and investigators or clinicians seeking breadth in their knowledge in the field. The book provides foundational knowledge of fertilization, gametogenesis, primordial germ cell formation, and ontogeny of reproductive organs. Key principles of developmental biology, genetics, endocrinology, protein biochemistry, and molecular and cellular biology are included to tell holistic stories of reproduction among eukaryotes. Later chapters tackle how the field applies these findings to address societal issues.

From Evolution of Mechanisms to Clinical Impact

Concepts in Reproduction

Advanced Biotechnology

Machine Learning and Big Data-enabled Biotechnology

Advances in Biomedical Applications

Nanotheranostics

Woodhead Publishing Series in Biomaterials

Engineered Biomaterials for Drug Delivery covers a core selection of engineering approaches and methods to optimize materials for drug delivery, including grafting, cross-linking, thiolation, conjugation, and the functionalization of biomaterials. A wide range of engineered biomaterial types are described, from biopolymers and nanobiomaterials, to metals, ceramics, and composites. Biocompatibility, toxicity, and regulatory considerations are also thoroughly discussed, ensuring the reader is fully equipped for efficient biomaterials selection and utilization in drug delivery applications. This is a must-have reference for those working in the fields of materials science, biomedical engineering, pharmaceutical science, pharmacology, chemical engineering, and clinical science.

Engineered Biomaterials for Drug Delivery

Concrete, hands-on strategies for making healthcare more accessible for everyone The Borderless Healthcare Revolution: The Definitive Guide to Breaking Geographic Barriers Through Technology&nbsp;is your field guide to a future in which a clinic visit is never farther away than the nearest screen and a surgeon's skill can cross oceans in real time. Drawing on two decades at the intersection of medicine and technology. including years as a senior leader at Oracle's global health division, Dr Sarah Matt translates frontier-grade innovation into day-to-day practice for clinicians, health-system strategists, and policymakers who refuse to accept geography as destiny. Inside you will find concrete playbooks rather than platitudes; every framework has been piloted in settings that range from Manhattan cath labs to Kenyan community clinics. You will also meet the patients and providers whose lived stories prove that digital transformation works only when it works for everyone. What you will learn: <ul> <li>The tech that already moves care without moving patients, telemedicine, remote surgery, ambient AI, and how adoption curves exploded after 2020, with more than three quarters of US hospitals now running telehealth programs</li> <li>Human-centered design tactics that translate pixels into trust, from inclusive language pivots to offline-first apps that respect bandwidth deserts</li> <li>A five-pillar access audit that flags physical, financial, cultural, digital, and trust barriers in any market, plus scorecards to track progress</li> <li>Strategy checklists forged during Dr Matt's tenure at Oracle for aligning payers, regulators, and vendors around sustainable reimbursement models</li> <li>Future-readiness briefs on robotics and mixed-reality training at a moment when the surgical robotics market is projected to triple by 2031</li> </ul> Whether you lead a rural health network, build digital products, or craft policy, The Borderless Healthcare Revolution: The Definitive Guide to Breaking Geographic Barriers Through Technology&nbsp;gives you the tools to expand access today and blueprint the borderless systems of tomorrow. Read it; then use it to deliver care that travels at the speed of need.

The Definitive Guide to Breaking Geographic Barriers Through Technology

The Borderless Healthcare Revolution

Diagnostic Imaging

Diagnostic Imaging: Brain

Synthetic Biopolymers for Drug Delivery covers a wide range of synthetic biopolymer types and their unique properties, including PLA, PLGA, PCL, carbopols, cyclodextrins, synthetic lipids, and much more. Biocompatibility, toxicity, and regulatory considerations are also thoroughly discussed, ensuring the reader is fully equipped for efficient biomaterials selection and utilization in drug delivery applications. This is a must-have reference for those working in the fields of materials science, biomedical engineering, pharmaceutical science, pharmacology, chemical engineering, and clinical science.

Synthetic Biopolymers for Drug Delivery

Lysosomal Pathophysiology of Parkinson’s Disease delves into the genetic and genomic revelations that have transformed our understanding of Parkinson’s Disease at the molecular level. The book highlights the critical role of the autophagy-lysosome pathway in the disease's pathogenic processes, drawing a comprehensive timeline of disease onset and progression. It offers a detailed examination of how disruptions in this pathway contribute to the hallmarks of Parkinson’s Disease, providing invaluable insights for researchers and clinicians alike. Subsequent chapters extend these insights by comparing Parkinson’s Disease to other neurodegenerative disorders such as Alzheimer’s Disease and Frontotemporal Dementia. By exploring protein pathology and synaptic alterations, the book underscores the broader implications of autophagy-lysosome dysfunction. Additionally, it discusses how the molecular perspectives gleaned from Parkinson’s Disease can inform our understanding of these other conditions, presenting a unified approach to studying neurodegeneration.

Lysosomal Pathophysiology of Parkinson’s Disease

Current Tools and Their Capabilities

Brain Imaging Essentials

Time wants you dead. Not just you, but your friends, family, pets - everyone you've ever met...

'A beautifully written book about life and death: busts myths, explores the stories of science and history, and ultimately is rich and uplifting.' Dr Adam Rutherford

With over 17,000 known diseases affecting humans, and countless poisons, carcinogens and toxins in our environment, it's a miracle that our bodies manage to keep us alive. And that is, of course, if they don't betray us themselves, whether through cancers or autoimmune conditions.

Biomedical researcher Professor John Tregoning tells the unlikely story of how, against all odds, we manage to stay alive. Taking an organ-by-organ tour of the human body, Tregoning embarks on his own experimental quest, testing 'life-extending' diets and exercise regimes to separate fact from fad. Exploring the multitude of ways our bodies can kill us, from inherited genetic conditions, through heart attacks, arrythmias and angina, onto the delicate workings of the brain, Live Forever?&nbsp;offers compelling insight into how our bodies work, how we can best look after them - and ultimately live longer, healthier lives.

***

'I heartily recommend this deep dive into wellness... It turns out that none of us are getting out of here alive, but John has bravely put his mind and body on the line to discover the secrets of staying healthy and happy as we get older. A funny, fascinating and educative book.' Ben Willbond, co-creator of Ghosts

'The idea that a book about death and dying could be a delightful read seems ridiculous, and yet John Tregoning has pulled off this trick with humour, flair and elegance.' Nessa Carey, author of The Epigenetics Revolution

'An enjoyable and entertaining mixture of scientific facts about ageing and completely unscientific self-experimentation... recognizing that although none of us will live forever, there are ways we can improve our chances of living well while we are still around.' Dame Sarah Gilbert

A Curious Scientist’s Guide to Wellness, Ageing and Death

Live Forever?

The Future of Seeing

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