Inspired by the leading authority in the field, the Centre for Process Systems Engineering at Imperial College London, this volume includes theoretical developments, algorithms, methodologies and tools in process systems engineering and applications from the chemical, energy, molecular, biomedical and other areas. The emphasis throughout is firmly placed on the importance of fundamental research and of developing mechanisms for the transfer of the new technology to industry. The clearly structured chapters span a whole range of length scales seen in manufacturing industries, from molecular and nanoscale phenomena to enterprise-wide optimization and control.