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Polycystic Ovary Syndrome (PCOS)

Current Status and Phytomedicine

Benign and malignant colorectal diseases, including inflammatory bowel diseases, continue to increase in both incidence and prevalence and require medical, and in some, endoscopic, or surgical treatment. Today’s clinicians must be prepared to diagnose and manage the frequent endoscopic or surgical procedure-associated complications associated with these procedures. Corrective Endoscopy and Surgery in Inflammatory Bowel and Colorectal Diseases: Advanced Management of Complications provides authoritative, step-by-step guidance on the complex complications encountered by gastroenterologists, inflammatory bowel disease specialists, endoscopists, general surgeons, gastrointestinal surgeons, and colorectal surgeons, offering real-world principles and techniques of corrective endoscopy or corrective surgery in one convenient volume.<ul><li>Provides expert guidance on the diagnosis and treatment of commonly encountered post-endoscopic or surgical procedure-associated complications, including balloon dilation and electroincision of strictures, resection and anastomosis, strictureplasty, and reconstruction procedures performed for Crohn’s disease, ulcerative colitis, colon cancer, or diverticular disease</li><li>Brings together multidisciplinary techniques and modalities for the management of these complex procedure-associated complications</li><li>Contains dozens of practical, up-to-date chapters covering the current literature; the authors’ vast personal experience in principles, techniques, instruments, and devices; and future implications</li><li>Provides clinical features of procedure-associated complications, which require scientific investigation on their etiology and pathogenesis</li><li>Features nearly 200 high-quality illustrations and procedural videos that provide essential visual guidance</li><li>A unique, must-have resource for gastroenterologists, GI endoscopists, general surgeons, colorectal surgeons, GI and colorectal fellows, IBD fellows, and advanced endoscopy fellows</li><li>An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish up to 6 weeks following the publication date</li></ul>

Advanced Management of Complications

Corrective Endoscopy and Surgery in Inflammatory Bowel and Colorectal Diseases

Handbook of Clinical Neurology

Immunotherapies for Neurologic Diseases: Volume TBD

The Clinics: Internal Medicine

In this issue of Endocrinology and Metabolism Clinics, guest editors Drs. Caroline M. Apovian and Dong Wook Kim bring their considerable expertise to the topic of Update on Obesity. Top experts in the field cover the latest research regarding weight loss drugs, drug safety, pharmacotherapy, AI, and nutritional/lifestyle changes for managing obesity.<ul><li>Contains 15 relevant, practice-oriented topics including drug safety and pharmacovigilance of anti-obesity medications; obesity stigma; non-pharmacological treatment for obesity; artificial intelligence and obesity management; intermittent fasting and obesity; and more</li><li>Provides in-depth clinical reviews on obesity, offering actionable insights for clinical practice</li><li>Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews</li></ul>

Update on Obesity, An Issue of Endocrinology and Metabolism Clinics of North America: Volume 54-1

The most comprehensive history of transgender medicine to date, as told by more than forty scholars, physicians, psychologists, and activists from trans, gender-diverse, and allied medical communities.

From Margins to Mainstream

A History of Transgender Medicine in the United States

Cushing Syndrome: History, Diagnosis, and Treatment is written by top experts on the latest in genetics, molecular advances, and the diagnosis and treatment of Cushing syndrome. The book takes a historical approach to discuss the tremendous and unprecedented research development for this rare condition and includes information on recently approved treatments. It attempts to provide information on most issues surrounding Cushing syndrome and how to deal with its complications, the widening understanding of functional hypercortisolemia and other causes of endogenous cortisol production and its old and new treatment modalities, from pituitary to adrenal tumors, ectopic ACTH production, subclinical, cyclical Cushing syndrome, to aging and metabolic syndrome. The book has a section dedicated to our patients with the patients’ experiences, which will add to the outcome research presented by the physicians. This is a must have reference for scientists and researchers with the latest information in diagnosing and treating this difficult-to-diagnose and difficult-to-treat condition and gives the clinician, a patient-centric approach to communicate with this particular group of patients.

History, Diagnosis and Treatment

Cushing Syndrome

Essentials of Neuroanesthesia, Second Edition continues to offer valuable insights into the anesthetic management of neurosurgical and neurologic patients, covering all topics related to neuroanesthesia and providing essential knowledge on the brain and spinal cord. The book includes chapters on anatomy, physiology, and pharmacology, along with specific chapters addressing various neurosurgical and neurological problems and their anesthetic management. This updated edition introduces new chapters on artificial intelligence in neurosciences, the role of simulation in clinical neurosciences, robotic neurosurgery, trigeminal neuralgia, coexisting transplanted organs, brain resuscitation after cardiac arrest, and more. In addition to the foundational knowledge, the book addresses related issues such as the evidence-based practice of neuroanesthesia, sterilization techniques, biostatistics, and ethical issues. It is a valuable resource for trainees, clinicians, and researchers in the fields of neuroanesthesia, neurocritical care, critical care, neurosurgery, and neurology. The comprehensive coverage and updated content make it an indispensable guide for understanding and managing the complexities of neuroanesthesia.

Essentials of Neuroanesthesia

From Bench to Bedside

Nutritional Neuroscience

Circadian rhythms, sleep, and sleep disorders covers the topic in two sections focusing on basic science and clinical application. In the basic section, new developments and research findings focusing on basic circadian rhythm and sleep physiology in animals and humans is highlighted. The chapters are written in short mini-review formats in order to concisely describe the fundamentals, and current hot topics. The basic part starts with a chapter on the fundamentals and new discoveries on oscillating circuitries in the sleeping rodent and human brain. This sets the stage for chap 2, focusing on circadian and homeostatic aspects of human sleep regulation. Chap 3 extends these aspects to human cognition. The next chapter reports on visual and non-visual effects of light on human behavior, particularly endocrine and electrophysiological correlates. Chap 5 covers chronic sleep restriction effects on functional connectivity states. The last two chapters (6 and 7) give a broad overview on sleep modeling across physiological levels, with a focus on a quantitative model of sleep-wake dynamics based on the physiology of the brainstem ascending arousal system. The clinical section of the book describes the circadian rhythm sleep-wake disorders, from epidemiology to clinical picture and treatment. Disorders covered include delayed and advanced sleep phase syndrome, Irregular sleep-wake rhythm disorder, shift work disorder, restless legs syndrome, nocturnal eating syndrome, narcolepsy, and sleep apnea. Pharmacological and non-pharmacological treatments of insomnia are explored, as well as the role of sleep-wake modulation in the pathogenesis and clinical profile of neurodegenerative disorders, such as Parkinson’s disease and Alzheimer’s disease.

Circadian Rhythms, Sleep, and Sleep Disorders: Volume 206

Integrated Science

This book seeks to represent the main concepts and theories related to psychoneuroimmunology with the aim of their application in clinical settings and formation of novel theories to further elucidate the mutual connection of the psyche and the physiology of humans' body. Psychoneuroimmunology, as an integration of popular research fields such as psychology, immunology, neurology, and neuroscience, is a perfect example of interdisciplinary and transdisciplinary studies that could potentially result in developing alternative diagnostic tools and treatment strategies besides facilitating the understanding of the pathophysiology of some conditions that might not properly be understood with a single point of view. Considering the stressful lifestyle and the high prevalence of neuropsychiatric, metabolic, and immune-related disorders, psychoneuroimmunology could be the path to the management of these conditions and reduction of the burden of the diseases.

Volume 2: Interdisciplinary Approaches to Diseases

PsychoNeuroImmunology

Advances in Experimental Medicine and Biology

This volume focuses on a challenging field in biomedicine: the genetic control of central immune tolerance.&nbsp;The thymus gland is a lymphoid organ implicated in T cells' maturation, differentiation, and selection. Its function is&nbsp;associated with the control of immune homeostasis in the body, establishing central immune tolerance, and preventing the onset of autoimmune diseases.&nbsp;This book focuses on thymus development, their cellular components and their respective function, and the peculiar gene expression profiling (transcriptome) found in the medullary thymic epithelial cells (mTECs) that are implicated in the self-representation in the thymus and the Autoimmune regulator (Aire) gene. Chapters also explore the mutations in the Aire gene, manifestation of autoimmune diseases, and the role of cell-cell interactions within the thymus with implications in the negative selection (elimination) of nascent autoreactive T cells in preventing aggressive autoimmunity. This new edition includes two new chapters devoted to the genome editing of the Aire gene through Crispr-Cas9 system, and thymic involution.All chapters have been updated to reflect the latest research in the field.&nbsp;

Thymus Transcriptome and Cell Biology

Nanomedicine Advancements and Intersectional Perspectives for Women's Health provides detailed insights and innovative treatments that specifically address health issues that women face. It provides valuable information and practical solutions based on scientific evidence providing comprehensive information about nanomedicine advancements specifically targeted towards improving health outcomes. It offers clear explanations of complex medical concepts in nanomedicine in a reader-friendly manner to help bridge the knowledge gap on this topic. By providing clear explanations, real-life examples, and practical insights, it empowers readers with valuable information that can help healthcare professionals make informed decisions working in relevant fields as well as researchers new to the field.

Nanomedicine Advancements and Intersectional Perspectives for Women's Health

Cholesterol Metabolism in Aging and Disease provides in-depth coverage on the mechanistic intersection between the aging process and cholesterol metabolism. The book covers the discovery of cholesterol, its biochemistry, and how it came to have such a prominent role in aging and disease. Important areas such as cholesterol biosynthesis and cellular cholesterol homeostasis are described in detail. Technological advancements in computational modeling are also discussed to help improve our understanding of cholesterol metabolism so that new therapeutic avenues are opened to help treat age-related diseases associated with the dysregulation of this key system. This is a must have reference for students and researchers interested in, or working in, various aspects of aging. In addition, it is ideal for clinician researchers and gerontologists.

Cholesterol Metabolism in Aging and Disease

Polycystic Ovary Syndrome (PCOS)

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