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Bhattacharya P: Metal Ions in
Biochemistry

Metal Ions in Biochemistry

Advances in Magnetic Resonance Technology and Applications

Advanced MR Techniques for Neurodegenerative Diseases covers state of the art developments in physiologic, metabolic, functional, and microstructural MRI of the brain. It provides an overview of these approaches and includes dynamic contrast enhanced (DCE) MRI, dynamic susceptibility contrast (DSC) MRI, arterial spin labeling (ASL), chemical exchange saturation transfer (CEST) MRI, magnetic resonance spectroscopy (MRS), resting state functional MRI (rsfMRI), microscopic diffusion imaging, and quantitative susceptibility mapping (QSM). Chapters then follow that present the application of these methods to Alzheimer’s Disease and vascular dementia, small vessel disease, Parkinson’s Disease, Lewy body dementia, Huntington’s Disease, Amyotrophic Lateral Sclerosis, and Multiple Sclerosis. Advanced MR Techniques for Neurodegenerative Diseases is a comprehensive resource on the latest advanced MR techniques and their application to neurodegenerative diseases, suitable for MR engineers and physicists as well as clinicians and neuroscientists who use MR techniques for diagnosis and research.

Advanced MR Techniques for Neurodegenerative Diseases: Volume 13

A Computational Approach

Modeling Structure-Function Relations in Ion Channels

Ostdeutschland hat weniger ein Abwanderungsproblem als ein Zuwanderungsdefizit. Die ostdeutschen Länder sollten deshalb, so die These des Sammelbandes, neben Anreizen zum Bleiben die Förderung von Flexibilität, Heimatbezug und Rückwanderung stellen. 
Aufbauend auf der empirischen Untersuchung zum Thema, die von dem Beauftragten für den Aufbau Ost, Bundesminister Wolfgang Tiefensee, gefördert wurde, präsentiert Hans-Liudger Dienel eine differenzierte Darstellung der Zuwanderung nach Ostdeutschland. Zuwanderung folgt nicht nur attraktiven Arbeitsplätzen sondern erfolgt auch entlang sozialer Netze und anderen "weichen" Faktoren. Der Fokus liegt im empirischen Teil auf zwei Zuwanderungsgruppen, die in der demografischen Forschung bisher unterschätzt wurden, den Studierenden und den Rückwanderer/innen als Teilgruppe der Zuwanderer/innen, und im handlungsorientierten Teil auf demografischen Maßnahmen.

Zu- und Rückwanderung in die neuen Bundesländer und die Rolle der Hochschulen

Bevölkerungsmagneten für Ostdeutschland

Series in Computational Biophysics

Multiscale methods are ideally suited to simulate the processes at work in many biomolecular systems, which often span a large range of time and length scales. Multiscale Methods in Molecular Biophysics highlights the advantages of these methods for integrating different levels of detail in a single simulation setting. It covers the practical methodology and successful applications in areas such as enzyme catalysis, protein folding, and ligand binding. The book is divided into three main sections: combination quantum and classical (atomistic) descriptions, approaches that combine atomistic and coarse-grained level of details, and multiscale methods where the resolution coupling is between global collective coordinates and local details.

Multiscale methods are ideally suited to simulate the processes at work in many biomolecular systems, which often span a large range of time and length scales. Multiscale Methods in Molecular Biophysics highlights the advantages of these methods for integrating different levels of detail in a single simulation setting. It covers the practical methodology and successful applications in areas such as enzyme catalysis, protein folding, and ligand binding. The book is divided into three main sections: combination quantum and classical (atomistic) descriptions, approaches that combine atomistic and coarse-grained level of details, and multiscale methods where the resolution coupling is between global collective coordinates and local details.

Multiscale Methods in Molecular Biophysics

This book serves as a unique resource on the field of novel drug delivery systems (NDDSs), catering to both academic audiences (researchers, teachers, students) and industry professionals (pharmaceutical policymakers, managers, R&amp;D, regulatory, business development, and marketing) involved in NDDSs. The evolving nature of diseases and the emergence of new health complications have driven a significant shift in drug therapy. Coupled with changes in human lifestyles and economic conditions, these factors have compelled the pharmaceutical industry to develop novel, efficient, and affordable drug products. The rise of promising technologies aimed at enhancing therapeutic performance further underscores the importance of novel drug delivery systems (NDDSs), making this field one of the most dynamic in pharmaceutical sciences today. This book offers a comprehensive exploration of NDDS applications, catering to both academic and industry professionals. It is designed to be both user-friendly and thorough, meeting the needs of diverse readers-from those seeking practical insights to those delving deeply into the field's various sectors. The content has been meticulously compiled, organized, and analyzed by a team of experts to ensure accuracy, relevance, and currency. The book provides up-to-date information suitable for a broad audience, reflecting the wide scope of the NDDS field. The first section covers the foundational principles of NDDS, including their scientific and therapeutic basis, as well as the epidemiological and economic trends driving their development. Subsequent sections explore market-oriented aspects, such as global trends and projections. Chapters 3 to 12 present a taxonomy of NDDS categorized by their routes of administration. The book concludes with a forward-looking report on the potential future directions of NDDS. Written in clear, concise language, the book is accessible to non-native English readers, ensuring broad usability. Original figures, created by experts with scientific and graphic design expertise, enhance the reading experience and aid in understanding complex concepts. Audience A wide variety of professional readers from universities and other research institutions to health industries (industrial pharmaceutical and related), to the relevant high-tech startups to health and pharma policymakers and managers will be among the audiences of this book.

Fundamentals and Applications

Novel Drug Delivery Systems

Synthesis to Applications

Lanthanide Complexes

This book is aimed at protecting the indispensable yet fragile Arctic marine environment, with sustainable restoration strategies for the conservation of the bioresources and revitalization of the ecological services.

This book is aimed at protecting the indispensable yet fragile Arctic marine environment, with sustainable restoration strategies for the conservation of the bioresources and revitalization of the ecological services.

Toxicology, Climate Change Impacts and Restoration Strategies

Safeguarding Arctic Marine Ecosystems

A follow-up to the experimental and instrumental aspects described in Basic Principles of Analytical Ultracentrifugation, the volume Sedimentation Velocity Analytical Ultracentrifugation: Discrete Species and Size-Distributions of Macromolecules and Particles describes the theory and practice of data analysis. Mathematical models for the sedimentation process and the evolution of detected signals are developed in a comprehensive framework, jointly with the description of current and historical strategies for how to extract from noisy experimental data the physical parameters of interest, such as size, mass, and shape, composition, and polydispersity of sedimenting particles. The methods are extensively illustrated, and supported with practical applications, as well as cross-references where to find the methods in the public domain software SEDFIT and SEDPHAT. The systems covered are discrete or polydisperse mixtures of sedimenting molecules or particles in dilute solution, such as proteins and other biomolecules and their stable complexes, man-made polymers, and nanoparticles, observed in different optical systems. These methods form the essential foundation for the analysis of dynamic interacting systems, which are covered in a separate volume.

A follow-up to the experimental and instrumental aspects described in Basic Principles of Analytical Ultracentrifugation, the volume Sedimentation Velocity Analytical Ultracentrifugation: Discrete Species and Size-Distributions of Macromolecules and Particles describes the theory and practice of data analysis. Mathematical models for the sedimentation process and the evolution of detected signals are developed in a comprehensive framework, jointly with the description of current and historical strategies for how to extract from noisy experimental data the physical parameters of interest, such as size, mass, and shape, composition, and polydispersity of sedimenting particles. The methods are extensively illustrated, and supported with practical applications, as well as cross-references where to find the methods in the public domain software SEDFIT and SEDPHAT. The systems covered are discrete or polydisperse mixtures of sedimenting molecules or particles in dilute solution, such as proteins and other biomolecules and their stable complexes, man-made polymers, and nanoparticles, observed in different optical systems. These methods form the essential foundation for the analysis of dynamic interacting systems, which are covered in a separate volume.

Sedimentation Equilibrium Analytical Ultracentrifugation

Der vorliegende zweite Band des Handbuchs Anarchismus stellt die verschiedenen Felder dar, in denen anarchistische Theorien wirkmächtig wurden. Überdies werden die anarchistischen Bewegungen in verschiedenen Weltregionen vorgestellt sowie zeitgenössische anarchistische Gruppierungen und Akteur*innen.

Der vorliegende zweite Band des Handbuchs Anarchismus stellt die verschiedenen Felder dar, in denen anarchistische Theorien wirkmächtig wurden. Überdies werden die anarchistischen Bewegungen in verschiedenen Weltregionen vorgestellt sowie zeitgenössische anarchistische Gruppierungen und Akteur*innen.&nbsp;

Begriffe und Konzepte

Handbuch Anarchismus 2

This edited book highlights the experimental approach, using Viruses, Bacteria, lower Eukaryotes and digital organisms. The contributors illustrate approaches revolutionizing our understanding of adaptation, recombination and mutation rates, speciation and the evolutionary transitions from prokaryotic to eukaryotic and from unicellular to multicellular life forms.

This edited book highlights the experimental approach, using Viruses, Bacteria, lower Eukaryotes and digital organisms. The contributors illustrate approaches revolutionizing our understanding of adaptation, recombination and mutation rates, speciation and the evolutionary transitions from prokaryotic to eukaryotic and from unicellular to multicellular life forms.

Essential Experimental Evolution

Methods in Cell Biology

Advanced Cancer Research Protocols: Volume 198

Woodhead Publishing Series in Biomaterials

Advances in Biomaterials for Drug Delivery: Properties, Clinical Applications and Challenges comprehensively reviews various biomaterials and biomaterial-derived carrier systems, with a specific focus on their application in drug delivery, and their clinical and regulatory challenges. A broad range of biomaterials for drug delivery are covered, including natural biomaterials, inorganic biomaterials, synthetic biomaterials, 3-D/4-D printed biomaterials, metal-based biomaterials, and polymeric and lipidic biomaterials. Various drug delivery approaches are detailed, from pulmonary and transdermal through to oral and systemic. Key to translational success of these novel platforms are the regulatory and clinical aspects of biomaterials development and application; these aspects are covered in each chapter, providing vital insight required to make informed decisions. Advances in Biomaterials for Drug Delivery: Properties, Clinical Applications and Challenges is an interesting resource for researchers and academics in the fields in biomaterials, materials science, polymer science, and pharmaceutical science, as well as clinicians and R&amp;D groups with an interest in the development of novel biomaterials for drug delivery.

Advances in Biomaterials for Drug Delivery: Properties, Clinical Applications and Challenges

Metal Ions in Biochemistry

Bibliografische Angaben

Schlagworte

Bibliografische Angaben

Schlagworte

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