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Manual of Nonhuman Primate Anesthesia,
Analgesia, and Postoperative Care

Manual of Nonhuman Primate Anesthesia, Analgesia, and Postoperative Care

Aortic Valve Repair provides a comprehensive summary on techniques developed during the first 500 cases of aortic ring annuloplasty. Aortic valve disease is usually surgically managed by aortic valve replacement, and it is well established in published literature regarding the long-term results, survival rate, durability of the protheses and reoperations rates. Over the past two decades, aortic valve repair (AVr) has evolved into a recognized surgical option for selected patients with aortic insufficiency or proximal aorta aneurysm. Studying the first 500 cases of aortic ring annuloplasty, the authors provide the most effective methods of leaflet and aortic root reconstruction to repair pathologies. Including original illustrations and videos, the book serves as an essential reference for cardiac surgeons in practice.

Aortic Valve Repair

Species and Systematics

A goal of macroevolutionary theory is to explain both diversity and disparity - different sometimes uncorrelated characteristics of lineages. These actively researched questions, the growing number of case studies, and the increasingly rigorous theory, has resulted in the re-examination of classical models for evolutionary tempo and mode. Time-calibrated molecular phylogenies are now used in conjunction with quantitative analyses of morphology to evaluate models of evolution. For example, mathematically simple efforts to understand biologically complex traits (such as body size) are common. The major objective of the proposed work is to present novel methods and case-studies of the tempo and mode of evolution of complex morphologies. Recent innovations in methods for describing and modeling complex morphologies, which have the potential to advance the field still further, will be the primary focus of this intended volume.

A goal of macroevolutionary theory is to explain both diversity and disparity. These actively researched questions, the growing number of case studies, and the increasingly rigorous theory, has resulted in the re-examination of classical models for evolutionary tempo and mode. Time-calibrated molecular phylogenies are now used in conjunction with quantitative analyses of morphology to evaluate models of evolution. This book will present novel methods and case-studies of the tempo and mode of evolution of complex morphologies, including recent innovations in methods for describing and modeling complex morphologies, which have the potential to advance the field still further.Key selling features:<ul> <li>Explores the relationship, if any, between species diversity and morphological disparity</li> <li>Includes relevant case studies</li> <li>Documents the role of geography and ecology in generating or retarding diversity and disparity</li> <li>Evaluates contingent, deterministic and intrinsic controls on macroevolutionary patterns</li> <li>Reviews models that predict diversity and disparity</li> </ul>

Macroevolution of Complex Morphologies

Globally, there are numerous infectious diseases, normally found in vertebrates other than humans, that have been documented to be transmitted to humans and cause human infections. These "zoonotic infections" are the topic of this book.This book is arranged to have chapters by the type of animal. Within each chapter is information on the animal(s), the normal flora of the animal(s), and the diseases that have been transmitted from this group of animals by bites and/or scratches, contact (including transmission via ectoparasites such as fleas and ticks), ingestion of the animal, and other documented transmission, such as infestation by members of the genus Sarcoptes as has been documented in humans exposed to dogs with "mange," in "cavalryman itch" from horses, from contact with dromedaries, etc.There are a number of additional issues that takeoff from a fundamental knowledge of zoonotic infections. These include a working knowledge of many of the agends of bioterrorism, as the events of 2001 demonstrated of the use of Bacillus anthracis spores in mailed letters. Another area of importance is that of emerging infections. An analysis of 335 origins of emerging infectious diseases between 1940 and 2004 revealed that these are dominated by infections that are zoonotic in origin, comprising some 60.3% of the emerging infections. Of these, 71.8% originated in wildlife.Given the importance of this topic in our understanding of infectious disease, a timely source is a necessary addition to the current available literature

Zoonoses: Animal Exposure and Human Disease

Precision Health and Medicine (PHM) represents a paradigm shift in healthcare, integrating interdisciplinary approaches to individualized patient care. The book is divided into three parts. Part I lays the groundwork, distinguishing PHM from traditional medicine and highlighting the roles of the various 'omics' disciplines as well as data science/artificial intelligence in PHM. In Part II, the focus shifts to specific applications of PHM, showcasing its therapeutical potential across diverse medical domains. Part III is forward-looking, considering social, ethical and legal issues in the implementation of PHM. It also reflects on the future of PHM, speculating on developments and challenges while outlining pathways for clinicians to integrate precision approaches into practice. We hope this book can serve as a reference guide to introduce healthcare practitioners to what PHM is, why PHM is important, where PHM can be applied, and how PHM will affect clinical medicine.

Precision Medicine For Health Practitioners

How do you count stem cells? This is a light, informative, and insider narrative of the discovery of the first method for routine, specific, and accurate quantification of therapeutic tissue stem cells. A technology sought after by the field of stem cell medicine for more than a century, James Sherley retraces his path toward the innovative breakthrough, weaving it with past and contemporaneous scientific history of relevant cancer and stem cell research. The story takes place within the larger context of scientific scholarship and research in powerful universities and institutes as an African American, offering an honest, if at times prickly, conversation about race and heritage in science. Written for both the novice and the expert, this book will intrigue readers with the nature of how new ideas are advanced in science and medicine and inform them of the fundamentals of scientific investigation and stem cell medicine, all provided in an accessible and entertaining form.

Counting Stem Cells: A Story Of Not Counting

Essays in Developmental Psychology

Presents a different perspective on the development of theory of mind based on an integration of empirical research that has been conducted on autism and William's syndrome.

Presents a different perspective on the development of theory of mind based on an integration of empirical research that has been conducted on autism and William's syndrome.

Autism and Williams Syndrome

Structural Biology of Amyloid Fibrils is a comprehensive reference on the structure of protein aggregates in different neurodegenerative diseases and their molecular bases. Chapters describe these structures in detail, highlighting their similarities and differences across different disease states, alongside an unprecedented overview of current developments and new hypotheses emerging in amyloid fibril structure, stability and mechanisms of formation. This volume also discusses how amyloid structure may affect the ability of fibrils to spread to different sites in a prion-like manner, as well as their role in disease. Featuring chapters on NMR, X-ray crystallography, and Cryo-EM methods, and discussing the structure of amyloid fibrils obtained directly from patients, the book allows readers to understand how polymorphism is associated with disease phenotype and how fibril structure affects and influences the cellular environment. Understanding the molecular architecture of amyloid fibrils and oligomers will be an important step towards developing therapeutic interventions based on targeting the fibrils and oligomers themselves, or the processes that generate them.

Structural Biology of Amyloid Fibrils

Practical Bioinformatics

The dinosaur-bird transition has been intensively studied using both fossil and embryological evidence. In recent years, the notion that birds are living dinosaurs has become the mainstream opinion in paleontology. But some embryologists and ornithologists remain skeptical and accuse paleontologists of ignoring conflicting evidence. This book resolves these conflicts. Careful re-evaluation of those features in seeming contradiction reveal that such characteristics actually support and corroborate the mainstream view that birds are in fact members of a dinosaurian lineage - they are living dinosaurs.

The dinosaur-bird transition has been intensively studied using both fossil and embryological evidence. In recent years, the notion that birds are living dinosaurs has become the mainstream opinion in paleontology. But some embryologists and ornithologists remain skeptical and accuse paleontologists of ignoring conflicting evidence. This book resolves these conflicts. Careful re-evaluation of those features in seeming contradiction reveal that such characteristics actually support and corroborate the mainstream view that birds are in fact members of a dinosaurian lineage - they are living dinosaurs.Key Selling features:<li>Explores the evidence supporting the dinosaur ancestry of birds</li><li>Illustrates how fossil and developmental evidence can be integrated</li><li>Reviews the specific nature of putative conflicting evidence</li><li>Synthesizes and resolves different sources of evidence </li>

Interpreting and Resoliving Developmental Evidence

Embryos of Living Dinosaurs

Neurotoxicity is epidemic in modern society. While in recent years there has been an explosion of basic toxicological research concerning neurotoxicity, this information has not been translated for clinical practice. As a result, health professionals are in the dark as to the potential causes of neurotoxicity, the signs and symptoms, and the treatment. The Neurotoxicity Guidebook, 2nd Edition will provide an overview of the field of applied neurotoxicology, in-depth case reports showing a method for evaluating cases of neurotoxicity, in-depth coverage of some specific neurotoxic agents, and an introduction to treating neurotoxicity cases.

Neurotoxicity is epidemic in modern society. While in recent years there has been an explosion of basic toxicological research concerning neurotoxicity, this information has not been translated for clinical practice. As a result, health professionals are in the dark as to the potential causes of neurotoxicity, the signs and symptoms, and the treatment. The Neurotoxicity Guidebook, 2nd Edition will provide an overview of the field of applied neurotoxicology, in-depth case reports showing a method for evaluating cases of neurotoxicity, in-depth coverage of some specific neurotoxic agents, and an introduction to treating neurotoxicity cases.

Neurotoxicity Guidebook, Second Edition

Glial Mechanisms in Sleep and Circadian Biology presents a comprehensive and up-to-date discussion of the role of glial cells in numerous, often unexpected, aspects of sleep. It seamlessly links glial cell activity to the multi-system processes that affect sleep. Experts in the field discuss how glial cells influence the sleep-wake cycle, the accumulation and discharge of sleep drive, the timing of sleep and wake across the 24-hour day, and how glial cells may govern important sleep functions (e.g., brain plasticity and metabolism). This is a book that could well change scientists’ and practitioners’ traditional beliefs about the factors underlying sleep. Users will find the book's content at the forefront of one of the hottest topics in basic sleep research. Over the last decade, scientists have made breakthrough discoveries revealing that sleep is not only a product of neurons, but of neuronal-glial interactions.

Glial Mechanisms in Sleep and Circadian Biology

Uncovering the Social Complexity of Whales and Dolphins

The Evolution of Cetacean Societies

Manual of Nonhuman Primate Anesthesia, Analgesia, and Postoperative ...

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