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Gesamtkatalog

Catalogue complet

Simulating Protein Folding in Variable
Environmental Conditions

Simulating Protein Folding in Variable Environmental Conditions

Transformation from Globular Proteins to Amyloids

Epidemiology of Infectious Disease

Mitochondrial Genomics: Insights into Dysfunction and Disease

Genomic and Precision Medicine in Clinical Practice

Medical and Health Genomics of South Asia, a new volume in the Genomic and Precision Medicine in Clinical Practice series, offers a thorough discussion of medical genomics as applied across South Asian nations, from India to Pakistan, Bangladesh, Sri Lanka, and Nepal, as well as in South Asian populations abroad. Here, global chapter authors consider genomic variation and the population heterogeneity of genetic, infectious, and lifestyle diseases in South Asia, along with successful modes of population health management for these inherited disorders and other applications of clinical genomics for improved individual health in the region. Adopting an applied approach, this book first reviews basic genomic models and population study formats, as well as the anthropological and genetic history of South Asia. The following sections examine genomic epidemiology and population health in the South Asian context; examples of genomic medicine's use in combating major health challenges in the region; genomic healthcare infrastructure; and related social, ethical, legal, and economic aspects central to impactful genomic medicine.

Medical and Health Genomics of South Asia

Methods in Cell Biology

Immuno-oncology and Immunotherapy Part G: Volume 202

Foundations and Frontiers in Enzymology

RNases in Health and Diseases: From Housekeeping Enzymes to Moonlight Proteins aims to provide overall coverage of structural and functional properties of RNases. This book introduces new concepts within the RNase field, such as their recently discovered multifaceted properties, their involvement in the generation of non-coding signaling RNAs and the proposed uses as diagnostic and therapeutic tools. This book is organised into three sections. Section I covers the structure of Rnases and provides an overview of the topic. Section II presents research methods and tools to study RNases. Finally, Section III delves into RNases and diseases. RNases in Health and Diseases: From Housekeeping Enzymes to Moonlight Proteins offers a wider perspective that serves as a resource for both researchers and students engaged in the study of RNases and are willing to acquire an overall background from this field.

From Housekeeping Enzymes to Moonlight Proteins

RNases in Health and Diseases

Matters of the Image introduces a new framework for thinking about digital images.

Designing Digital Images with Materiality, Energy, and Living Matter

Methods in Enzymology

Lipids and Membranes: Metabolism, Lipidation, and Lipid-Protein Interactions: Volume 728

Lipids and Membranes: Detection by Imaging and Lipidomics: Volume 727

Poly(vinylpyridine) is one of the most important polymers with many applications in the field of organic chemistry, polymer chemistry, medicine and industry. This book contains more than 1,650 references about "poly(vinylpyridine)", which have been reviewed and analyzed and includes complete details of reactions, applications and syntheses related to this polymer. In many cases, the reactions given in this book are explained in full details (reaction conditions) under the schemes, so that the reader of the book can understand the subject and purpose of the reaction and text with just a glance. This book is a very simple and complete resource on poly(vinylpyridine), which allows the reader to access information on this polymer quickly and easily. This book is useful for students (graduated students), academic and researchers in the field of chemistry and polymer, as well as researchers active in the industry.

Structure, Properties, Synthesis, and Applications

Poly(vinylpyridine)

Translational Epigenetics

Lifestyle Epigenomics, a new volume in the Translational Epigenetics series, comprehensively details the interplay between lifestyle factors and epigenetic modifications associated with the onset of noncommunicable diseases and aging, shedding light on potential preventive and therapeutic strategies for disease from an epigenomics perspective. Here, more than 35 international experts in the field consider how lifestyle choices or habits can condition or prevent disease, along with tools for new research, from bioinformatics methodology to non-invasive sampling. Early, foundational chapters are followed by all-inclusive sections on epigenetic machinery in health and disease; dietary factors and epigenetics; adiposity and physical activity and epigenetics; psychological stress, social environment, toxins and contaminants exposure effects on epigenetics; and transgenerational and childhood epigenetics. To support understanding, each chapter includes a summary and key points lists, terms and definition, as well as research case studies outlining core components of recent studies, detailing their conditions, research techniques involved, and outcomes.

Lifestyle Epigenomics

Every day, more and more kinds of historical data become available, opening exciting new avenues of inquiry but also new challenges. This updated and expanded book describes and demonstrates the ways these data can be explored to construct cultural heritage knowledge, for research and in teaching and learning. It helps humanities scholars to grasp Big Data in order to do their work, whether that means understanding the underlying algorithms at work in search engines or designing and using their own tools to process large amounts of information. Demonstrating what digital tools have to offer and also what 'digital' does to how we understand the past, the authors introduce the many different tools and developing approaches in Big Data for historical and humanistic scholarship, show how to use them, what to be wary of, and discuss the kinds of questions and new perspectives this new macroscopic perspective opens up. Originally authored 'live' online with ongoing feedback from the wider digital history community, Exploring Big Historical Data breaks new ground and sets the direction for the conversation into the future. Exploring Big Historical Data should be the go-to resource for undergraduate and graduate students confronted by a vast corpus of data, and researchers encountering these methods for the first time. It will also offer a helping hand to the interested individual seeking to make sense of genealogical data or digitized newspapers, and even the local historical society who are trying to see the value in digitizing their holdings.

Navigating In A Pathogenic World

Site Specific and Global Epigenomic Editing: Principles and Applications, Volume 33 highlights the expanding role that epigenetics plays in pathogenesis, the full range of sites for possible epigenetic modification, and the potential to target these sites to modulate disease progression. The book answers key questions, including which of the hundreds of epigenomic marks and features are relevant, and which are likely to serve a role in regulating gene expression, cell behavior and phenotypic outcomes. This volume is the first to provide a thorough, conceptual introduction to epigenetic regulation and a thorough accounting of sites for possible epigenetic edits and disease modulation. Included protocols and applied case studies examine early disease targets and likely pathways of therapeutic significance while also outlining common challenges in the field. The book addresses its topic in a comprehensive, but accessible manner, highlighting practical tools and burning questions remaining in the field to enable fresh research.

Principles and Applications

Site Specific and Global Epigenomic Editing: Volume 33

Simulating Protein Folding in Variable Environmental Conditions

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