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Pal A: Mitochondrial Genomics: Insights
into Dysfunction and Disease

Mitochondrial Genomics: Insights into Dysfunction and Disease

Concepts in Reproduction integrates the principal mechanisms of reproduction among eukaryotes, with a focus on animals and plants. The text emphasizes processes and approaches that evolved to address specific problems inherent in reproduction using examples from morphology, functional studies, and genetic studies. The many high-quality figures complement the text and provide visual storyboards. Footnotes and boxes are used throughout to provide depth and to enrich understanding. Information is compartmentalized to guide new readers through complex material while offering in-depth coverage of significant and impactful topics for experts.Key Features¿ Accessibility for a broad audience, using figures that complement the text to explain key concepts and mechanisms ¿ Integrative presentation that emphasizes the science behind the story¿ Breadth of coverage to promote comparative thought¿ Rich multiple-choice questions that span the contentConcepts in Reproduction is recommended for advanced undergraduate students, new graduate students, and investigators or clinicians seeking breadth in their knowledge in the field. The book provides foundational knowledge of fertilization, gametogenesis, primordial germ cell formation, and ontogeny of reproductive organs. Key principles of developmental biology, genetics, endocrinology, protein biochemistry, and molecular and cellular biology are included to tell holistic stories of reproduction among eukaryotes. Later chapters tackle how the field applies these findings to address societal issues.

From Evolution of Mechanisms to Clinical Impact

Concepts in Reproduction

Foundations and Frontiers in Enzymology

Enzyme Kinetics: Fundamentals, Applications, and Reactor Design is a comprehensive guide that provides readers with a solid grounding in the principles of enzyme kinetics and bioreactor design while also illuminating their practical applications. The book takes a step-by-step approach, starting from basic concepts and gradually moving to advanced topics, to ensure that readers develop a strong understanding and are well-equipped to apply this knowledge in real-world scenarios. "Enzyme Kinetics: Fundamentals, Applications, and Reactor Design" covers crucial areas including safety regulations and future trends, making it an all-in-one resource for anyone interested in these fields. It also provides foundational information, explains methods and computational approaches, and presents case studies and applications. This book is designed to serve as a valuable resource for a broad range of readers, including undergraduate and graduate students studying biochemistry, biotechnology, and chemical engineering, as well as professionals and researchers looking to deepen their knowledge and stay at the forefront of their field. Enzyme Kinetics: Fundamentals, Applications, and Reactor Design offers an integrative and up-to-date perspective on enzyme kinetics and bioreactor design, with an emphasis on real-world applications, cutting-edge developments, and safety regulations.

Fundamentals, Applications, and Reactor Design

Enzyme Kinetics

An Illustrated Guide

Ponds

Advances in Cancer Research

Innovative Nanotechnology: Transforming Skin Cancer Diagnosis and Treatment: Volume 169

Debating the use of genomic tools and their societal impactOver the past decade, the field of human genetics has produced an extraordinary range of discoveries-including the refinement of polygenic scores, which use a person's DNA to estimate their likelihood of developing a trait or disease. But are these new technologies ready to leave the research lab and be deployed in schools, fertility clinics, and the wider world? In What We Inherit, Sam Trejo and Daphne Martschenko offer different perspectives on the societal impact of the rapidly unfolding DNA revolution. Trejo, a sociologist and expert on the complex ways people's genes influence their life's trajectory, believes that new genomic tools-if used thoughtfully-can improve society; Martschenko, a bioethicist who specializes in the thorny social issues raised by biomedical advances, is more cautious. They debate both the risks and the opportunities posed by such new technologies as at-home genetic tests and polygenic embryo selection-all while engaging in a wide-ranging dialogue on ideology, biology, and social inequality. While grappling with these new technologies, Trejo and Martschenko remind us that we inherited from our ancestors not only DNA but also wrong-headed ideas about genes. Together, they caution against two particularly harmful genetic myths: that genes determine an individual's future, and that race and genetics are inherently connected. A polygenic score, for example, is not a definitive marker for disease. And race is a sociopolitical construct, not a biological identity. Trejo and Martschenko argue that, to avoid exacerbating social inequality, we need to begin regulating genomic tools sooner rather than later.

How New Technologies and Old Myths Are Shaping Our Genomic Future

What We Inherit

The Creatures’ Guide to Caring

Boorman’s Pathology of the Rat: Reference and Atlas, Third Edition, continues its history as the most comprehensive pathology reference on rat strains for researchers across science and medicine using rat models in the laboratory. It offers readers an added emphasis on the Sprague-Dawley and Wistar rat strains that is consistent with current research across academia, government, and industry. In addition, the book provides standard diagnostic criteria, basic content on histology, histological changes that result from drug toxicity and neoplasm, pathology terminology, and four-color photographs from the NTP archive and database. With updated references and photographs, as well as coverage of all rat strains, this book is not only the standard in the field, but also an invaluable resource for toxicologists, biologists, and other scientists engaged in regulatory toxicology who must make the transition from pathology results to the promulgation of meaningful regulations. The new edition includes topics not covered previously with contributors who at the forefront of each specific topic. ¿ This book is the most comprehensive publication on rat pathology, now revised to include all rat strains and with an added emphasis on the Sprague-Dawley and Wister. It is an invaluable resource for toxicologists, biologists, and other scientists engaged in regulatory toxicology who must make the transition from pathology results to promulgation of meaningful regulations.

Reference and Atlas

Boorman's Pathology of the Rat

Methods in Enzymology

Protein Termini Part B: Volume 719

Understanding the Impacts on Ecosystems and Societies

Non-Native Species

Practical Bioinformatics

Methods in Cell Biology

Immuno-oncology and immunotherapy Part F: Volume 201

Progress in Molecular Biology and Translational Science

Wearable, Ingestible and Implantable Technologies for Health and Wellness Monitoring Part B

Biosensing the Future: Volume 216

Mitochondrial Genomics: Insights into Dysfunction and Disease

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