In 2004, the FBI was tipped off to a gruesome pattern of murders along American roadways. Today at least 850 homicides have been linked to a solitary breed of predators: long-haul truck drivers. They have been given names like the Truck Stop Killer, who rigged a traveling torture chamber in the rear of his truck and is suspected to have killed fifty women, and The Interstate Strangler, who once answered a phone call from his mother while killing one of his dozen victims. The crisis was such that the FBI opened a special unit, the Highway Serial Killings Initiative. In each case, the victims, often at-risk women, are picked up at truck stops in one jurisdiction, sexually assaulted and murdered in another, and dumped along a highway in a third place. What's worse, the transient nature of the offenders and multiple jurisdictions involved make these cases difficult to solve. Based on his own on-the-ground research and drawing on his twenty-five-year career as an FBI special agent, Frank Figliuzzi investigates the most terrifying cases.