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Emerging Trends in Cancer Pharmacology

From Molecular Targets to Personalized Medicine

Next Generation Technology Driven Personalized Medicine And Smart Healthcare

A Comprehensive Guide for Novice Researcher in Clinical Trials serves as an essential resource for anyone looking to navigate the complex world of clinical trials. Designed specifically for novice research enthusiasts, this book provides a thorough introduction to the principles, training, and skills necessary for designing and conducting clinical trials. Spanning 13 detailed chapters, it covers the entire spectrum of clinical trial methodology while adhering to Good Clinical Practice (GCP) standards. The book begins with foundational concepts in health research methods and clinical epidemiology, laying the groundwork for understanding the significance and necessity of clinical trials in healthcare. It explores various research designs, types of bias, and the historical context that shaped modern clinical trial practices. In-depth discussions on clinical trial design, including parallel, crossover, and adaptive designs, equip readers with the knowledge to select the appropriate framework for their research. Essential sections on ethics, regulatory requirements, and protocol development ensure that researchers understand the critical responsibilities involved in conducting ethical and scientifically sound trials. The guide also delves into practical aspects such as clinical data management, monitoring, and statistical principles, empowering readers to manage data effectively and analyze results accurately. With insights into project management and regulatory affairs specific to clinical trials in Saudi Arabia, the book addresses local challenges and requirements, making it particularly relevant for health professionals in the region. By providing a stepwise approach to clinical trial conduction, this book aims to promote better access, understanding, and utilization of clinical trials within diverse health disciplines. With its comprehensive coverage and up-to-date information, Clinical Trials: A Comprehensive Guide for Novice Researchers not only equips readers with the necessary tools to enhance their research capabilities but also contributes to the overall improvement of healthcare delivery and patient outcomes globally.

A Comprehensive Guide for Novice Researcher in Clinical Trials

AAPS Advances in the Pharmaceutical Sciences Series

A Roadmap

Pediatric Formulations

Chromatographic Science Series

Active chemical compounds in the pharmaceutical products existing on the market need to be characterized with respect to their properties, or compared to other similar products, already available for direct use. The book describes sampling methodologies, preparation methods, separation possibilities and assay of these compounds at low concentration levels in complex matrixes. The steps covered are taken before launching a new pharmaceutical product on the market for estimating its pharmacokinetic behavior, or before authorizing for marketing of a generic pharmaceutical product.

Analytical Aspects of Bioequivalence

The study of organic compounds containing fluorine is full of surprises and has substantial theoretical significance as well as practical commercial value. The field has significantly matured in recent decades, prompting a need for a current textbook that can serve as an entry point into this fascinating sub-discipline. Introduction to Organofluorine Chemistry is intended to answer that need.This comprehensive and well-structured book is divided into seven sections of 28 chapters. Readers are first introduced to the privileged role and landmark developments of the ninth element, its physical chemistry, and its fascinating effects on reactive intermediates. The second half of the text covers the synthesis, reactions and analysis of organofluorine compounds. The astonishing ability of fluoroorganics to exert their importance in a plethora of fields is sketched out in the final segment.

Introduction To Organofluorine Chemistry

AI-Powered Drug Delivery to Neuro and Cardiovascular Systems: Perspectives and Future Challenges is a comprehensive reference covering the transformative potential of Artificial Intelligence (AI) in the realms of neuro and cardiovascular drug delivery. Designed to integrate and review the latest literature, this book provides an in-depth understanding of how AI is set to revolutionize clinical practices, protocols, and regulatory guidelines in therapeutic drug delivery. As AI and robotics continue to evolve, their role in enhancing precision, personalization, and efficiency in cardiovascular and neurological drug delivery becomes increasingly essential. The book opens with an introduction to the foundational concepts of AI in drug delivery, followed by a detailed examination of current AI practices in managing cardiovascular and neurological diseases. It progresses to explore AI-enhanced drug design and testing for cardiovascular conditions, and the application of AI in cardiac drug delivery vehicles. Insights into bioengineered heart and vessels, AI-inspired redox homeostasis, and targeted drug replenishment in cardiac matrix remodeling are thoroughly discussed. The text also covers novel avenues in mitochondrial drug retention, AI-assisted pharmaco and gene therapy for neurodegenerative diseases, and the role of AI in heart health. Further sections address the augmented optimization of medical side effects, neuromodulation with pharmacotherapy from an AI perspective, and smart systems for managing cerebrovascular accidents. The book concludes with a discussion on translational challenges and future directions in the field. This book is an invaluable resource for healthcare professionals, researchers, and students keen on understanding the dynamic interplay between AI and drug delivery systems. By offering insights into AI-driven prediction models, personalized drug regimens, and advanced robotic delivery mechanisms, it sets the stage for the next generation of cardiovascular and neurotherapeutic management. The perspectives, concepts, and innovations discussed are integral to shaping the future of cardiovascular and neurological healthcare.

Perspectives and Future Challenges

AI Powered Drug delivery to Neuro and Cardiovascular Systems

The world has turned into a hub of various chronic diseases such as cancer, diabetes, asthma, cardiovascular diseases, epilepsy, to name a few. The adoption of an unhealthy lifestyle is the main contributing factor that leads to these diseases. Despite the advancement in the development of drugs and therapies, the complete cure for these diseases is yet to be met. Nonetheless, as Edison's aphorism goes, 'The doctor of the future will no longer treat the human frame with drugs, but rather will cure and prevent disease with nutrition', the new era of medicine has started focusing on 'nutraceuticals'. Nutraceuticals have received undue interest due to potential nutritional, safety, therapeutic effects and affordable prices. Recent studies have shown promising results for nutraceutical products in preclinical and clinical trials. This book is an attempt to bring about the beneficial effect of nutraceuticals in human health evidenced by clinical trials.

Nutraceuticals For The Prevention And Treatment Of Chronic Diseases: Lessons Learned From Bedside

Pharmaceutical QbD with Design of Experiments: Statistical Tools and Applications in Drug Delivery Systems offers comprehensive coverage of best practices in pharmaceutical manufacturing. The first section discusses the principles and basics of Quality by Design (QbD). Part two covers the foundational statistical principles and tools for the Design of Experiments (DoE). Section three is dedicated to the applications of QbD for conventional formulations. The next section provides ample coverage of applications to Novel Drug Delivery Systems (NDDS), including micro and nano-particles. The final section discusses the application of QbD for the optimization of pharmaceutical processes and equipment. Researchers in pharmaceutical manufacturing will benefit from this thorough statistical review, while students in this field will gain practical insights the experienced chapter authors provide in case studies. Industry professionals can find solutions to their particular problems within the insights and strategies shared in this book.

Statistical Tools and Applications in Drug Delivery Systems

Pharmaceutical QbD with Design of Experiments

Nanotechnology-Based Innovations in Chronic Obstructive Pulmonary Disease (COPD) Treatment and Management

Woodhead Publishing Series in Biomaterials

Engineered Biomaterials for Drug Delivery covers a core selection of engineering approaches and methods to optimize materials for drug delivery, including grafting, cross-linking, thiolation, conjugation, and the functionalization of biomaterials. A wide range of engineered biomaterial types are described, from biopolymers and nanobiomaterials, to metals, ceramics, and composites. Biocompatibility, toxicity, and regulatory considerations are also thoroughly discussed, ensuring the reader is fully equipped for efficient biomaterials selection and utilization in drug delivery applications. This is a must-have reference for those working in the fields of materials science, biomedical engineering, pharmaceutical science, pharmacology, chemical engineering, and clinical science.

Engineered Biomaterials for Drug Delivery

This book discusses current concepts and practice on analytical approaches for characterization of medicinal plants and plant-based products. It reviews all aspects of extraction, spectroscopic analysis, isolation, chemometrics, DNA bar-coding, in-line processing, and bioassays.

Analytical Techniques for Quality Control of Medicinal Plants

Woodhead Publishing Series in Biomedicine

Chemistry, Biology and Omics

Medicinal Plants

Emerging Trends in Cancer Pharmacology

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