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Advances and Technical Standards in Neurosurgery

Advances and Technical Standards in
Neurosurgery

Volume 55

The scope of this book is to disseminate dorsal rhizotomy for treating children with disabling, intractable spasticity caused by various pathologies. The volume is composed of five sections. The first section describes history and neuroanatomical background of dorsal rhizotomy and spasticity, while the second one is about the selection and pre-operative evaluation of surgical candidates. The third section is the key for readers who are going to learn this surgical procedure, and describes the various types of surgical procedures and the intraoperative neurophysiology used in the surgery. The fourth section is focused on postoperative rehabilitation, functional evaluation and long-term outcome after dorsal rhizotomy. The last section describes the future perspective of this technique and explains how to start up a rhizotomy team.Since the concern about dorsal rhizotomy has been re-emerging recently, this publication is highly expected and will be useful for both beginners in rhizotomy and experienced neurosurgeons.

Vol. 51

Dorsal Rhizotomy: Neurosurgery for Childhood Spasticity

This series has already become a classic. In general, one volume is published per year. The advances section presents fields of neurosurgery and related areas in which important recent progress has been made. The technical standards section features detailed descriptions of standard procedures to assist young neurosurgeons in their post-graduate training. The contributions are written by experienced clinicians and are reviewed by all members of the editorial board.

Advances and Technical Standards in Neurosurgery, Vol. 33

This volume of Advances and Technical Standards in Neurosurgery covers some important new developments in functional neurosurgery and endovascular therapy. In the Technical Standards section a variety of topics are considered, including optic pathway gliomas, pineal lesions, cavernous sinus meningiomas, and the eternal problem of minor and repetitive head injury. Endovascular treatment of a variety of lesions is now common practice, and the state of the art in endovascular treatment for acute ischemic stroke is reviewed. An appraisal of the evidence on whether there is a place for microsurgical vascular decompression for essential hypertension raises interesting questions. The volume is completed by contributions on neurosurgical treatment of cluster headaches and occipital nerve stimulation.

Volume 42

This volume of Advances and Technical Standards in Neurosurgery is devoted entirely to the spine. Like other volumes in the series, it presents important recent progress in the field and offers detailed descriptions of standard procedures to assist young neurosurgeons. Among the advances considered are approaches to spinal navigation, including intraoperative imaging based navigation, and concepts of spinal robotics. The value of sagittal balance as a parameter for the neurosurgeon is examined, and a novel surgical approach to longitudinal pathologies within the spinal canal is presented. Developments in surgery for kyphosis are also discussed, with a focus on pedicle subtraction osteotomy. The technical standards section critically reviews the latest evidence regarding cervical disc arthroplasty and pedicle-based non-fusion stabilization devices. The book concludes by discussing the treatment of craniovertebral junction instability as a result of juvenile chronic arthritis.

Volume 41

Management of congenital and acquired diseases of the craniovertebral junction (CVJ), comprising the occipital bone surrounding the foramen magnum, the atlas, and the axis vertebrae, constitutes one of the more complex areas of neurosurgery. This is particularly true in the pediatric population, in which the neurosurgeon is faced with a wide variety of congenital developmental anomalies and acquired diseases and must take into account the need to avoid significant interference in still growing structures. Pediatric neurosurgeons are increasingly called upon to face this stimulating region, the diseases of which may now be managed with rewarding results even in the first years of life owing to progress in the neurosciences, availability of advanced neuroimaging diagnostic tools, and improved surgical and anesthesiological techniques.This dedicated volume in the series Advances and Technical Standards in Neurosurgery (ATSN) provides a comprehensive approach to CVJ diseases and their management based on the multidisciplinary cooperation of neurosurgeons, anatomists, neuroradiologists, and neuroanesthesiologists. The contributing authors represent the most renowned clinical and surgical experts from Europe and beyond. In accordance with the traditional structure of ATSN, the 12 chapters of the volume are organized into advanced (7) and standard (5) contributions. The main topics highlighted are embryology, normal and abnormal development of the CVJ, including the related vessels, modern radiological contributions to diagnosis, genetic and metabolic factors which may impact on the surgical strategies, the opportunities offered by traditional operative techniques, and the recently introduced minimally invasive and endoscopic surgical modalities. Special emphasis is also placed on the evolution of the principles of surgical treatment as matured during the past decade by experiences in the still open field of pediatric neurosurgery.

Surgical Management of Craniovertebral Junction Diseases in Children

Pediatric Craniovertebral Junction Diseases

This volume reviews standard treatments for spinal dural arteriovenous fistulas, examining the anatomy of arteries and veins of the sylvian fissure, as well as microsurgical advances and the development of modern therapeutic strategies in intracranial meningiomas. The advances section presents a strategy for minimizing hearing loss after stereotactic radiosurgery for vestibular schwannomas, as well as a description of the mode of action and biology of ALA, including its interaction with tumor cells and the limits of this method. A dedicated chapter addresses the essential question of the limits (and merits) of various tractography techniques, and of their importance for non-specialists, who may be tempted to use them uncritically. A further chapter examines molecular markers, which have become standard in neuropathological reports on intracranial tumors, reviewing the prognostic and predictive value of these modern molecular markers in gliomas. Additional chapters round out the coverage, offering a comprehensive overview of standard and advanced techniques.&nbsp;

Volume 43

The contributions in this volume cover recent advances and changing concepts on diagnosis and treatment of resistant epilepsy in children. Topics treated are new insights on mechanisms of epileptogenesis in developing brain, multimodality imaging in pediatric intractable epilepsy, pediatric intractable epilepsy syndromes, pediatric temporal lobe epilepsy surgery, critical review of palliative surgical techniques for intractable epilepsy, treatment modalities for intractable epilepsy in hypothalamic hamartomas, contemporary management of epilepsy in tuberous sclerosis.

Pediatric Epilepsy Surgery

Advances J. Maarrawi, P. Mertens, R. Peyron, L. Garcia-Larrea, M. Sindou: Functional exploration for neuropathic pain. - Z. H. Rappaport: The neuroscientific foundations of free will. - A. Hejcl, P. Jendelova, E. Sykova: Experimental reconstruction of the injured spinal cord. - M. Visocchi: Advances in video-assisted anterior surgical approach to the craniovertebral junction. Technical Standards N. Akalan: Myelomeningocele (Open spina bifida): Surgical management. - M. Stoffel, C. Stüer, F. Ringel, B. Meyer: Treatment of infections of the spine. - I. Massimi, F. Novegno, C. di Rocco: Chiari Type 1 malformation in children.

S. Price: Advances in imaging low-grade gliomas - M. J. Riemenschneider, G. Riefenberger: Molecular neuropathology of low-grade gliomas and its clinical impact - I . R. Whittle: What is the place of conservative management for adult supratentorial low-grade glioma - D. Kurzwelly, U. Herrlinger, M. Simon: Seizures in patients with low-grade gliomas -- incidence, pathogenesis, surgical management, and pharmacotherapy - L. Bello et al: Present day's standards in microsurgery of low-grade gliomas - B. Baumert and R. Stupp: Is there a place for radiotherapy in low-grade gliomas? - F. W. Kreth et al: The place of interstitial brachytherapy and radiosurgery for low-grade gliomas - M. Klein: Health- related quality of life aspects in patients with low-grade glioma.

Low-Grade Gliomas. Edited by J. Schramm

Advances and Technical Standards in Neurosurgery, Vol. 35

. . . . . . . . . . . . . . . . 6 Patternsofcelldeath. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 Autophagy:apotentialTrojanhorseformalignantgliomas. . . . . . . . . . . . . . . . 11 Therapeuticbene?tsoftemozolomide. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13 Localtherapiesforglioblastomas. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15 Ongoingclinicaltrialsforglioblastomas. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16 Growthfactorreceptorinhibitors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17 PI3K=Akt,mTORandNF- Binhibitors. . . . . . . . . . . . . . . . . . . . . . . . . . . 17 Matrixmetalloproteinase(MMP)inhibitors(MMPI). . . . . . . . . . . . . . . . . . . 18 Angiogenesistargeting . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19 Cellularandvaccinationtherapies. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20 Genetherapy. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20 Reducingmalignantgliomacellmotilityinordertorestore pro-apoptoticdrugsensitivity. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20 Thesodiumpumpconstitutesapotentialtargettocombat malignantgliomas. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21 Thesodiumpump. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22 Cardiotonicsteroids:ligandsofthesodiumpump. . . . . . . . . . . . . . . . . . . . 24 VIII Contents Thesodiumpumpisinvolvedincancercellproliferation, migrationanddeath. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24 Braintumorstemcellsapotentialtargettocombatmalignantgliomas. . . . . . . 26 Conclusions. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27 References. . . . . . . . . . . . . . . .

Volume 34

Epilepsy surgery is defined as any neurosurgical intervention whose pri­ mary objective is to relieve medically intractable epilepsy (European Fed­ eration of Neurological Societies Task Force 2000). The aim of epilepsy surgery is to reduce the number and intensity of seizures, minimise neuro­ logical morbidity and antiepileptic drug (AED) toxicity, and improve quality of life. By definition, epilepsy surgery does not include normal surgical treatment of intracranial lesions where the primary goal is to di­ agnose and possibly remove the pathological target, often an advancing tumour. In these patients, epileptic seizures are only one symptom of the lesion and will be treated concomitantly as part of the procedure. Temporal lobe epilepsy (TLE) is recognised as the most common type of refractory, focal epilepsy. In one third of all cases the neuronal systems responsible for the seizures that characterise this form of epilepsy fail to respond to currently available AEDs (Andermann F 2002). New imaging methods, especially magnetic resonance imaging (MRI), identify localising abnormalities in an increasing proportion of patients with intractable focal epilepsy. Consequently, the accuracy of the preoperative diagnostic pro­ cedures has been significantly improved during the last decade; and suit­ able candidates for surgery can be selected more reliably. Currently the main resources in most epilepsy surgery centres have been used to evaluate candidates for TLE surgery.

As an addition to the European postgraduate training system for young neurosurgeons, we began to publish in 1974 this series of Advances and Technical Standards in Neurosurgery which was later sponsored by the European Association of Neurosurgical Societies. This series was first discussed in 1972 at a combined meeting of the Italian and German Neurosurgical Societies in Taormina, the founding fathers of the series being Jean Brihaye, Bernard Pertuiset, Fritz Loew and Hugo Krayenbuhl. Thus were established the principles of European coï¿½ operation which have been born from the European spirit, flourished in the European Association, and have been associated throughout with this senes. The fact that the English language is now the international medium for communication at European scientificconferences is a great asset in terms of mutual understanding. Therefore we have decided to publish all contriï¿½ butions in English, regardless of the native language of the authors. All contributions are submitted to the entire editorial board before publication of any volume for scrutiny and suggestions for revision. Our series is not intended to compete with the publications of original scientificpapers in other neurosurgical journals. Our intention is, rather, to present fields of neurosurgery and related areas in which important recent advances have been made. The contributions are written by specialists in the given fieldsand constitute the first part of each volume.

This book serves as an invaluable resource for physicians utilizing ultrasound in their practice, emphasizing its crucial role in imaging and guidance for pain interventions. It introduces and explores the concept of "sonoanatomy," offering a practical and concise guide for pain and musculoskeletal specialists.The application of ultrasound has grown significantly across various clinical disciplines in recent years. In pain management, it has become a practical and widely adopted tool. By using ultrasound, clinicians can improve the success rates of pain interventions while reducing the risk of complications. Compared to fluoroscopy and CT, ultrasound is more convenient; however, it requires a solid understanding of clinical anatomy and hands-on experience for effective and safe application."Sonoanatomy" refers to the integration of detailed anatomical knowledge with ultrasound imaging. Mastery of sonoanatomy is essential for accurately targeting structures during pain interventions. This synthesis of anatomy and practical ultrasound techniques is the cornerstone of successful procedures.The book prioritizes sonoanatomy while detailing relevant techniques. Designed as a concise guide, it is tailored for physicians across specialties, including residents and specialists in physical medicine and rehabilitation, anesthesiology, pain medicine, and anatomy. It also serves as a valuable reference for all clinicians involved in ultrasound-guided procedures.

Practical Guide for Pain Interventions: Head and Neck Sonoanatomy

"Neurosurgery Rounds: Questions and Answers, Third Edition by Mark R. Shaya, Cristian Gragnaniello, and Remi Nader reflects major advances in neurosurgery and neurological diseases since the publication of the prior edition. The reader friendly book features contributions from renowned experts and covers major neurosurgical areas pertinent to neurosurgical residents, such as surgical anatomy, pathophysiology, and surgical techniques. This book is specifically designed to help prepare for both the written and oral board examinations. The oral board examination involves interaction with examiners; therefore, passing the exam is heavily dependent on the ability to communicate succinctly and precisely what to do in specific clinical situations. Organized in nine chapters, this case-based book provides diverse coverage of multiple disciplines involved in the knowledge, care, and treatment of neurosurgical patients, including new topics, such as COVID-19"--

Neurosurgery Rounds: Questions and Answers

The Clinics: Surgery

In this issue of Neurosurgery Clinics, guest editors Drs. P.B. Raksin and Laura B. Ngwenya bring their considerable expertise to the topic of Neurocritical Care of Trauma. Critical care management of individuals who have experienced a traumatic insult to the brain and/or spinal cord is essential in the acute phase post-injury to ensure appropriate resuscitation, support operative interventions, and mitigate the risk of secondary insults. This issue will review aspects of clinical care as well as explore topics of interest with respect to medical ethics and systems of care delivery.<ul><li>Contains 16 relevant, practice-oriented topics including fundamentals of care for severe traumatic brain injury and acute spinal cord injury; fluids, electrolytes, and nutrition; disorders of electrophysiology following severe traumatic brain injury; rehabilitation in the ICU; neuroprognostication and ethical considerations in neurotrauma; and more</li><li>Provides in-depth clinical reviews on neurocritical care of trauma, offering actionable insights for clinical practice</li><li>Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews</li></ul>

Neurocritical Care of Trauma, An Issue of Neurosurgery Clinics of North America: Volume 36-3

Highly specialized fields like pediatric neurosurgery evolve in the hands of a small but international group of dedicated experts. As such, comprehensive training requires a large degree of mobility. Hannes Haberl, the editor of this book, looks back on 20 years of productive, sometimes surprising,&nbsp;but&nbsp;always profitable&nbsp;encounters with&nbsp;respected colleagues&nbsp;in order to&nbsp;review and&nbsp;extend his personal range of&nbsp;approaches and&nbsp;surgical techniques.This book is the result of very personal communications between the editor and 25 of the most&nbsp;experienced pediatric neurosurgeons. Introducing their&nbsp;very&nbsp;personal attitudes and approaches, the&nbsp;authors offer also surgical&nbsp;tips, tricks&nbsp;and insights&nbsp;which&nbsp;have proven useful in daily surgical practice&nbsp;and education. Although&nbsp;–&nbsp;or&nbsp;precisely&nbsp;because&nbsp;-&nbsp;not a conventional textbook, it is&nbsp;highly recommendable for&nbsp;neuro-surgeons, neurologists,&nbsp;pediatricians and&nbsp;interested members of related disciplines.&nbsp;&nbsp;&nbsp;

Tips, Tricks and Insights, Shared by Leading Experts

The DNA of Pediatric Neurosurgery

Comprehensive ENT

This book provides a comprehensive and up-to-date overview of general information, along with an evaluation of diagnostic and therapeutic options for individuals suffering from otologic diseases. Covering fundamental sciences, clinical applications of otology treatments, and the latest research, it is designed to aid physicians in making well-informed decisions about patient care management.Divided into seven parts, the book addresses topics such as hearing reconstruction and its acoustic impact, cochlear implants, brainstem implants, genetic causes of hearing loss, including prevention and rehabilitation, sudden deafness, autoimmune inner ear disease, and the molecular basis of otosclerosis. Contributors also explore the contemporary clinical application of genetics and available testing for hearing loss.This volume will serve as an invaluable resource for otolaryngologists, head and neck surgeons, audiologists, neurologists, neurosurgeons, and residents, offering a comprehensive guide to enhance their understanding and practice.

Otology Updates

This book offers an update about peripheral nerve sheath tumors (PNST), both in their benign and malignant forms (MPNST). 
Starting from the most innovative preclinical studies about genetic and omics characterization, it then explores the traditional and advanced imaging modalities (ultrasound, DTI, etc) and the electrophysiological assessment. Another relevant part is reserved to the description of the most recent surgical techniques (fluorescent dye for intraoperative surgical guidance, neurophysiological monitoring, esoscopic view). Finally, new oral treatment for PNST related to neurocutaneous diseases (as selumetinib in plexiform neurofibromas) is described. &nbsp; 
Written by worldwide experts in each specifical field, if offers a multidisciplinary vision to PNST, approaching the topic in a translational way, from preclinical studies to the current medical practice. 
The ideal readers are all health operators involved in the treatment of these tumors- from neurosurgeons to radiologists, neurologists, geneticists, biologists, etc) as well as medical students in these disciplines.

From Preclinical Studies to Advanced Therapies

Peripheral Nerve Sheath Tumors

Cortex, Nuclei and Connections

MRI Neuroanatomy

Veränderungen der Augenlider benötigen eine spezielle Betrachtung durch den okuloplastischen Chirurgen im Schnittpunkt zwischen Funktion und Ästhetik der periorbitalen Region.Dieses Buch bietet intensive Einblicke in die Lidchirurgie und richtet seinen Fokus praxisnah auf die Indikationsstellung, OP-Techniken, das Komplikationsmanagement und die Nachsorge der häufigsten lidchirurgischen Erkrankungen und Eingriffe. Dabei wird sowohl auf die funktionelle als auch auf die ästhetische okuloplastische Chirurgie eingegangen.Die behandelten Themen reichen von häufigen Krankheitsbildern wie Entropium, Ektropium, Ptosis und Dermatochalasis bis hin zur Ober- und Unterlidblepharoplastik, Tumorchirurgie und komplexen Lidrekonstruktionen. Die praxisorientierte Gliederung ermöglicht eine schnelle und gezielte Einarbeitung in alle Bereiche der Lidchirurgie und bietet sowohl Einsteigern als auch fortgeschrittenen Lidchirurgen eine wertvolle Hilfestellung.Verbessern Sie Ihre okuloplastische Expertise mit Tipps von erfahrenen Operateuren.&nbsp;Die Autoren: Matthias Keserü ist Facharzt für Augenheilkunde und war langjähriger Oberarzt für Lid-, Tränenweg- und Orbita-Chirurgie an den Augenkliniken des Universitätsklinikums Hamburg-Eppendorf und der Asklepios Klinik Hamburg-Barmbek. Seit 2023 arbeitet Dr. Keserü in privater Praxis in Hamburg.Simon Dulz ist habilitierter Facharzt für Augenheilkunde und ehemaliger Oberarzt&nbsp;für Lid-, Tränenweg- und Orbita-Chirurgie an der Augenklinik des Universitätsklinikums Hamburg-Eppendorf. Aktuell arbeitet er als leitender Arzt für&nbsp;Lid-, Tränenweg- und Orbita-Chirurgie in der Klinik Schwerin und Kiel und ist Gründer einer lidchirurgischen Spezialpraxis in Hamburg und Frankfurt.

Ein Praxisbuch

Lidchirurgie

This book provides a concise resource on the latest robotic techniques relevant to thoracic surgery. It covers the fundamental aspects of these techniques along with detailed step-by-step instruction on how to perform a range of procedures. Chapters detail the available techniques for lung, oesophageal and bronchieactasis surgery. Accompanying videos enable the reader to visualise how to successfully the methodologies covered and further develop their understanding.Operative Manual of Robotic Thoracic Surgery concisely covers the latest developments in this rapidly evolving field, providing numerous practical suggestions on how to set-up a robotic surgery program at a hospital and effectively manage the associated costs. It therefore represents a valuable resource for all trainee and practicing medical professionals interested in performing these procedures on a day-to-day basis.

Operative Manual of Robotic Thoracic Surgery

The Many Faces of the Elongated Styloid Process

EAGLE Syndrome

This third edition atlas provides the most current techniques and methods for&nbsp;treating&nbsp;both benign and malignant urologic conditions using the most modern robotic platforms and equipment available to date. Robotic surgery has had a very well-established and increasing role in the field of urology for the past two decades, in many cases almost completely replacing traditional open and laparoscopic approaches. Robotic&nbsp;surgery has continued&nbsp;to expand&nbsp;and has been applied to&nbsp;urologic conditions in both adult and pediatric patients. In addition, advancements in robotic technology have opened the door to single-site (vs multi-port) surgeries, further reducing the morbidity and improving the cosmesis for many urologic procedures.The book begins with a guide to getting started in robotic surgery with new chapters on robotics training and performance improvement. From here, the book comprehensively and systematically covers a wide range of surgical procedures, including surgeries of the upper and lower urinary tract using the&nbsp;daVinci&nbsp;Xi platform, robotic pediatric urologic surgeries, and single port&nbsp;(daVinci SP) robotic surgery. A discussion of the past, present, and future of robotic surgical platforms wraps up this comprehensive guide. Each chapter is written by internationally-recognized leaders in the field in a consistent step-by-step format to help the audience learn how to expand their robotic&nbsp;surgical techniques and capabilities&nbsp;for their patients.The Comprehensive Atlas of Robotic Urologic Surgery, Third Edition is a singular resource for individuals who are involved in robotic surgery including urologic surgeons, trainees, nurses, physician assistants, and anesthesiologists.

A Step-by-Step Guide to Adult and Pediatric Urologic Procedures

The Comprehensive Atlas of Robotic Urologic Surgery

An Orthoplastic Approach

Treatment of Fracture-Related Infection

Advances and Technical Standards in Neurosurgery

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