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Swayne O: How to Use a Fork

How to Use a Fork

Stories of Mending the Broken Brain

From social media sensations Cate Osborn and Erik Gude, with Rennie Dyball, comes a fresh and practical guide to managing ADHD for adults.

The ADHD Field Guide for Adults

Survival and Transformation After Trauma

Unspeakable

The deep sea is one of humanity's last frontiers. For most of our history it has been a remote realm, invoking awe and terror as it lays shrouded in darkness. But here, where the light cannot reach, lies a strange, wonderful and breath-taking portal into Earth's past, teeming with scientific marvels and lessons for the future of life on this planet. In The Dark Frontier, marine microbiologist and expert deep-sea explorer Jeffrey Marlow plunges us into the unreachable realm and invites us into close-up encounters with its hidden brilliance. There are translucent shrimp that dance through sulfurous vents, crabs that stretch twelve feet from claw to claw and the eerie chalk-white towers of the 'Lost City'. Immersive and illuminating, Marlow's journeys heed warnings too: our reach is exceeding our grasp. We are irrevocably changing the deep sea before we even know it. This expansive book offers crucial and surprising insights into the birthplace of life on ancient Earth. It shows how life can thrive in even the most extreme conditions and expands our understanding of possibilities - and our responsibilities - on earth and beyond.

Unlocking the Secrets of the Deep Sea

The Dark Frontier

How Curiosity, Exploration and Experience Make a Fuller, Better Life

Life in Three Dimensions

The Joy Instinct

Stories of the Strangeness and Wonder of Our Brains

The Mind Electric

Basic Neurochemistry: Principles of Molecular, Cellular, and Medical Neurobiology, Ninth Edition is a classic advanced neurochemistry and neurobiology textbook that has a renewed focus on clinical applications. The early chapters focus on fundamental membrane chemistry, cellular signaling, and development of the nervous system. Later chapters cover cell injury and inflammation, neurodegenerative diseases, sensory transduction, and neural processing/behavior. By understanding mechanisms at the molecular and systems level, scientists can develop new pharmacotherapies to treat diseases such as Alzheimer's Disease, Parkinson's Disease, Multiple Sclerosis as well as neuropsychiatric diseases (e.g., schizophrenia, depression, pain, addictions). This book provides a foundation of all key principles of neurochemistry and neurobiology--within the context of human diseases--for advanced students and graduate students in neuroscience, biomedical sciences, as well as clinical neuroscientists and neurologists.

Principles of Molecular, Cellular, and Medical Neurobiology

Basic Neurochemistry

The Surprising Science of Human Diversity

Adaptable

How ideas from science can transform your life

The Art of Physics

Structural Biology of Amyloid Fibrils is a comprehensive reference on the structure of protein aggregates in different neurodegenerative diseases and their molecular bases. Chapters describe these structures in detail, highlighting their similarities and differences across different disease states, alongside an unprecedented overview of current developments and new hypotheses emerging in amyloid fibril structure, stability and mechanisms of formation. This volume also discusses how amyloid structure may affect the ability of fibrils to spread to different sites in a prion-like manner, as well as their role in disease. Featuring chapters on NMR, X-ray crystallography, and Cryo-EM methods, and discussing the structure of amyloid fibrils obtained directly from patients, the book allows readers to understand how polymorphism is associated with disease phenotype and how fibril structure affects and influences the cellular environment. Understanding the molecular architecture of amyloid fibrils and oligomers will be an important step towards developing therapeutic interventions based on targeting the fibrils and oligomers themselves, or the processes that generate them.

Structural Biology of Amyloid Fibrils

How to Use a Fork

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