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This book covers design and development of novel cost-effective aptamer-based biosensors for disease diagnostic and prognostic including understanding of health care management in terms of timely update of disease situation in a particular geographical area.

Aptasensors for Point-of-Care
Diagnostics

Aptasensors for Point-of-Care Diagnostics

Fundamentals and Biomedical Applications

1. Overview of aptamer-based biosensors 2. Biomarkers for aptamer-based diagnostic applications 3. Designing and synthesis of aptamer via various approaches (SELEX and ExSELEX) 4. A comparative study of aptasensor versus immunosensor for biomarker detection 5. Aptamer-based point-of-care diagnostic devices for infectious diseases 6. Aptamer-based colorimetric biosensor 7. Aptamer beacon probes for the detection and visualization of miRNA 8. Microfluidics-enabled aptamer-based sensing devices - the aptafluidics microdevices 9. Fabrication of aptamer-based electrochemical biosensor for health care monitoring 10. Challenges and advances in aptamer-based biosensing approaches 11. Current perspectives of aptasensors as diagnostic tools for oncological diseases

Electromagnetic Analysis of Electric Machines

From a New York Times bestselling nature writer comes a celebration of what goes on outside in the dark, from blooming moon gardens to nocturnal salamanders, from glowing foxfire and synchronous fireflies that blink in unison like an orchestra of light. In this glorious celebration of the night, New York Times bestselling nature writer Leigh Ann Henion invites us to leave our well-lit homes, step outside, and embrace the dark as a profoundly beautiful part of the world we inhabit. Because no matter where we live, we are surrounded by animals that rise with the moon, and blooms that reveal themselves as light fades. Henion explores her home region of Appalachia, where she attends a synchronous firefly event in Tennessee, a bat outing in Alabama, and a moth festival in Ohio. In North Carolina, she finds forests alight with bioluminescent mushrooms, neighborhood trees full of screech owls, and valleys teeming with migratory salamanders. Along the way, Henion encounters naturalists, biologists, primitive-skills experts, and others who've dedicated their lives to cultivating relationships with darkness. Every page of this lyrical book feels like an opportunity to ask: How did I not know about this before? For example, we learn that it can take hours, not minutes, for human eyes to reach full night vision capacity. And that there are thousands of firefly species on earth, many with flash patterns as unique as fingerprints. In an age of increasing artificial light, Night Magic focuses on the amazing biodiversity that still surrounds us after sunset. We do not need to stargaze into the distant cosmos or dive into the depths of oceans to find awe in the dark. There are dazzling wonders in our own backyards. And readers of World of Wonders, Entangled Life, and The Hidden Life of Trees will discover joy in Night Magic.

From a New York Times bestselling nature writer comes a celebration of what goes on outside in the dark, from blooming moon gardens to nocturnal salamanders, from glowing foxfire and synchronous fireflies that blink in unison like an orchestra of light.&nbsp; In this glorious celebration of the night, New York Times bestselling nature writer Leigh Ann Henion invites us to leave our well-lit homes, step outside, and embrace the dark as a profoundly beautiful part of the world we inhabit. Because no matter where we live, we are surrounded by animals that rise with the moon, and blooms that reveal themselves as light fades. Henion explores her home region of Appalachia, where she attends a synchronous firefly event in Tennessee, a bat outing in Alabama, and a moth festival in Ohio. In North Carolina, she finds forests alight with bioluminescent mushrooms, neighborhood trees full of screech owls, and valleys teeming with migratory salamanders. Along the way, Henion encounters naturalists, biologists, primitive-skills experts, and others who’ve dedicated their lives to cultivating relationships with darkness.&nbsp; &nbsp; Every page of this lyrical book feels like an opportunity to ask: How did I not know about this before? For example, we learn that it can take hours, not minutes, for human eyes to reach full night vision capacity. And that there are thousands of firefly species on earth, many with flash patterns as unique as fingerprints. In an age of increasing artificial light, Night Magic focuses on the amazing biodiversity that still surrounds us after sunset. We do not need to stargaze into the distant cosmos or dive into the depths of oceans to find awe in the dark. There are dazzling wonders in our own backyards. And readers of World of Wonders, Entangled Life, and The Hidden Life of Trees will discover joy in Night Magic.

Adventures Among Glowworms, Moon Gardens, and other Marvels of the Dark

Night Magic

Glial Mechanisms in Sleep and Circadian Biology presents a comprehensive and up-to-date discussion of the role of glial cells in numerous, often unexpected, aspects of sleep. It seamlessly links glial cell activity to the multi-system processes that affect sleep. Experts in the field discuss how glial cells influence the sleep-wake cycle, the accumulation and discharge of sleep drive, the timing of sleep and wake across the 24-hour day, and how glial cells may govern important sleep functions (e.g., brain plasticity and metabolism). This is a book that could well change scientists’ and practitioners’ traditional beliefs about the factors underlying sleep. Users will find the book's content at the forefront of one of the hottest topics in basic sleep research. Over the last decade, scientists have made breakthrough discoveries revealing that sleep is not only a product of neurons, but of neuronal-glial interactions.

Glial Mechanisms in Sleep and Circadian Biology

This book covers the basics of nanotechnology and its role in biomedical engineering. It clubs different applications of nanotechnology in medicine, disease diagnostics, artificial implants; nano-enabled implantable devices and nanorobots as future mode of treatment of various diseases. It provides a comprehensive overview to the reader about the basics of above areas as well as advanced implementation strategies. Case studies included in the book will help readers get a proper understanding of the subject and how nanotechnology is a boon for medical and bioengineering.

This book covers the basics of nanotechnology and its role in biomedical engineering. It clubs different applications of nanotechnology in medicine, disease diagnostics, artificial implants; nano-enabled implantable devices and nanorobots as future mode of treatment of various diseases. It provides a comprehensive overview to the reader about the basics of above areas as well as advanced implementation strategies. Case studies included in the book will help readers get a proper understanding of the subject and how nanotechnology is a boon for medical and bioengineering.

Nanotechnology in Biomedicine

Chapman & Hall/CRC Statistics in the Social and Behavioral Sciences

This advanced textbook goes beyond the current limits of item response modeling to enhance understanding and help readers be more creative in the development and usage of the models. The book first provides a basic survey of the approach and then lays out a large space of important models and their applications. It finishes with information about using different computational approaches to estimating the models, including aspects of testing, as well as several appendices containing helpful codes and examples.

This advanced textbook goes beyond the current limits of item response modeling to enhance understanding and help readers be more creative in the development and usage of the models. The book first provides a basic survey of the approach and then lays out a large space of important models and their applications. It finishes with information about using different computational approaches to estimating the models, including aspects of testing, as well as several appendices containing helpful codes and examples.

An Explanatory Approach

A Generalized Framework for Item Response Models

Based on practical field experience and several case studies, this book presents state-of-the-art artificial intelligence techniques, validating their efficiency and accuracy in real-world industrial applications. The authors show how a meta-heuristic approach can enhance automatic fault monitoring in man-made systems. For each phase of fault monitoring, they propose a meta-heuristic approach that is tested experimentally in an actual industrial environment. While the proposed methods are validated on specific industrial problems, their applicability is wide and general.

Based on practical field experience and several case studies, this book presents state-of-the-art artificial intelligence techniques, validating their efficiency and accuracy in real-world industrial applications. The authors show how a meta-heuristic approach can enhance automatic fault monitoring in man-made systems. For each phase of fault monitoring, they propose a meta-heuristic approach that is tested experimentally in an actual industrial environment. While the proposed methods are validated on specific industrial problems, their applicability is wide and general.

Using Meta-Heuristic Optimization

Automatic Monitoring, Fault Diagnostics, and Maintenance

Digital twins represent an emerging technology of immense potential across various industries. Their significance is particularly pronounced within Industry 4.0 and smart manufacturing paradigms, which strive to elevate efficiency and quality through seamless digital integration. By amassing and scrutinizing extensive data streams, digital twins empower data-centric decision-making-a pivotal asset in contemporary industry. Digital Twins of Advanced Materials Processing bridges the gap in comprehensive resources concerning advanced materials processing, a domain characterized by rapid evolution. It provides pragmatic remedies and real-world case studies, catering to tangible implementation needs. Moreover, digital twins hold the capacity to amplify efficiency and innovation within materials processing-a perspective deeply explored within this book, rendering it invaluable for professionals, researchers, and students alike. The prospects of employing digital twins in materials processing span diverse horizons: refining materials innovation, streamlining processes, enabling data-driven maintenance, enhancing product quality, and unearthing insights rooted in data. The book also undertakes the challenge of addressing key issues encompassing data amalgamation and integrity, model validation and calibration, software and data safeguarding, scalability, and cost considerations.

Digital Twins of Advanced Materials Processing

Flexible DC Traction Power Supply Systems in Urban Rail Transit: Design, Operation and Control is an essential guide on the cutting-edge of the field that clarifies the current standard for power converters, traction control, and energy systems for rail transport before introducing basic concepts, configurations, and opportunities for flexible DC traction power supply systems. Other sections provide a detailed guide to operating principles and core functions in comparison to traditional diode rectifier-based traction power supply systems. This is a critical resource for energy and electrical engineers, researchers, and students developing the sustainable infrastructure of the future. Key techniques are analyzed with attentive reference to rail application context and appropriate case studies. The book closes with two full chapters of novel case studies from China that support practical application and further development by readers. Working from foundational principles to real-world applications.

Design, Operation and Control

Flexible DC Traction Power Supply System in Urban Rail Transit

Species and Systematics

A goal of macroevolutionary theory is to explain both diversity and disparity - different sometimes uncorrelated characteristics of lineages. These actively researched questions, the growing number of case studies, and the increasingly rigorous theory, has resulted in the re-examination of classical models for evolutionary tempo and mode. Time-calibrated molecular phylogenies are now used in conjunction with quantitative analyses of morphology to evaluate models of evolution. For example, mathematically simple efforts to understand biologically complex traits (such as body size) are common. The major objective of the proposed work is to present novel methods and case-studies of the tempo and mode of evolution of complex morphologies. Recent innovations in methods for describing and modeling complex morphologies, which have the potential to advance the field still further, will be the primary focus of this intended volume.

A goal of macroevolutionary theory is to explain both diversity and disparity. These actively researched questions, the growing number of case studies, and the increasingly rigorous theory, has resulted in the re-examination of classical models for evolutionary tempo and mode. Time-calibrated molecular phylogenies are now used in conjunction with quantitative analyses of morphology to evaluate models of evolution. This book will present novel methods and case-studies of the tempo and mode of evolution of complex morphologies, including recent innovations in methods for describing and modeling complex morphologies, which have the potential to advance the field still further.Key selling features:<ul> <li>Explores the relationship, if any, between species diversity and morphological disparity</li> <li>Includes relevant case studies</li> <li>Documents the role of geography and ecology in generating or retarding diversity and disparity</li> <li>Evaluates contingent, deterministic and intrinsic controls on macroevolutionary patterns</li> <li>Reviews models that predict diversity and disparity</li> </ul>

Macroevolution of Complex Morphologies

Biotechne: Interthinking Art, Science and Design

Viruses and Viral Phenomena Across Science, Technology, and the Arts

Viral Behaviors

Genetics and Society

This book provides a timely analysis of the past, present and future of the stem cell. It uncovers an intriguing and paradoxical story of scientific setbacks and advance, medical breakthroughs and technical innovation amid ongoing uncertainty about the nature of the stem cell.

This book provides a timely analysis of the past, present and future of the stem cell. It uncovers an intriguing and paradoxical story of scientific setbacks and advance, medical breakthroughs and technical innovation amid ongoing uncertainty about the nature of the stem cell.

From Radiobiology to Regenerative Medicine

The Scientific, Clinical and Commercial Development of the Stem Cell

This book introduces factor analysis methods for the study of multivariate stochastic processes whose structure evolves over time. It introduces the theory of factor analysis and evolutionary stochastic processes and combines that to study evolutionary factor models. The book includes many real examples to illustrate applications from such fields as macroeconomics, finance, neuroscience, communication, and psychology. MATLAB® and R code is included throughout the book for implementation of the methods.

This book introduces factor analysis methods for the study of multivariate stochastic processes whose structure evolves over time. It introduces the theory of factor analysis and evolutionary stochastic processes and combines that to study evolutionary factor models. The book includes many real examples to illustrate applications from such fields as macroeconomics, finance, neuroscience, communication, and psychology. MATLAB® and R code is included throughout the book for implementation of the methods.

Evolutionary Factor Analysis

Aptasensors for Point-of-Care Diagnostics

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