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Alfaro C: Anatomy and Histology of the
Pig

Anatomy and Histology of the Pig

A Concise Full-Color Atlas

1. Introduction and General Anatomy 2. Anatomic Atlas 3. Normal Histology of the Pig

Structural Biology of Amyloid Fibrils is a comprehensive reference on the structure of protein aggregates in different neurodegenerative diseases and their molecular bases. Chapters describe these structures in detail, highlighting their similarities and differences across different disease states, alongside an unprecedented overview of current developments and new hypotheses emerging in amyloid fibril structure, stability and mechanisms of formation. This volume also discusses how amyloid structure may affect the ability of fibrils to spread to different sites in a prion-like manner, as well as their role in disease. Featuring chapters on NMR, X-ray crystallography, and Cryo-EM methods, and discussing the structure of amyloid fibrils obtained directly from patients, the book allows readers to understand how polymorphism is associated with disease phenotype and how fibril structure affects and influences the cellular environment. Understanding the molecular architecture of amyloid fibrils and oligomers will be an important step towards developing therapeutic interventions based on targeting the fibrils and oligomers themselves, or the processes that generate them.

Structural Biology of Amyloid Fibrils

The unique and award-winning Unofficial Guides series is a collaboration between senior students, junior doctors and specialty experts. This combination of contributors understands what is essential to excel on your course, in exams and in practice - as well as the importance of presenting information in a clear, fun and engaging way. Packed with hints and tips from those in the know, when you are in a hurry and need a study companion you can trust, reach for an Unofficial Guide. This unique book provides a succinct introduction to how to pursue research, teaching or audit opportunities. You’ll find guidance on how to do a literature search, key concepts in statistics, and tips for science communication, critical appraisal and clinical governance - all written in a concise way that’s perfect for undergraduates. Fully updated for its second edition, the Unofficial Guide to Medical Research, Audit and Teaching will be a day-to-day reference you use long after you’ve graduated.<ul><li>Step by step guide covering everything you need to know to undertake research, audit or teaching - easily accessible and all in one place</li><li>Clearly laid out and easy to understand</li><li>Practical tips and tricks - covers not just what you need to do, but also how to do it</li><li>Includes a concise guide to medical statistics</li><li>Convenient checklists for analysing the different types of research studies</li><li>Guidance on finding research opportunities and how to approach a supervisor</li><li>Tips for effective teaching</li><li>Guidance for portfolios</li></ul><ul><li>Updated information regarding specialised foundation programme</li><li>Advice on working abroad - including Australia and New Zealand</li><li>Information regarding hierarchy of evidence and n=1 studies</li><li>Updated examples to explain statistical analysis techniques</li><li>Introduction to clinical commissioning and policy development</li><li>Use of social media and online communities for science communication</li><li>Digital teaching</li><li>New and emerging research areas including computational modelling</li></ul>

The Unofficial Guide to Medical Research, Audit and Teaching

Series in Computational Biophysics

Multiscale methods are ideally suited to simulate the processes at work in many biomolecular systems, which often span a large range of time and length scales. Multiscale Methods in Molecular Biophysics highlights the advantages of these methods for integrating different levels of detail in a single simulation setting. It covers the practical methodology and successful applications in areas such as enzyme catalysis, protein folding, and ligand binding. The book is divided into three main sections: combination quantum and classical (atomistic) descriptions, approaches that combine atomistic and coarse-grained level of details, and multiscale methods where the resolution coupling is between global collective coordinates and local details.

Multiscale methods are ideally suited to simulate the processes at work in many biomolecular systems, which often span a large range of time and length scales. Multiscale Methods in Molecular Biophysics highlights the advantages of these methods for integrating different levels of detail in a single simulation setting. It covers the practical methodology and successful applications in areas such as enzyme catalysis, protein folding, and ligand binding. The book is divided into three main sections: combination quantum and classical (atomistic) descriptions, approaches that combine atomistic and coarse-grained level of details, and multiscale methods where the resolution coupling is between global collective coordinates and local details.

Multiscale Methods in Molecular Biophysics

A Practical Introduction

Membrane Protein Bioinformatics

Progress in Molecular Biology and Translational Science

Wearable, Ingestible and Implantable Technologies for Health and Wellness Monitoring Part B

Biosensing the Future: Volume 216

A follow-up to the experimental and instrumental aspects described in Basic Principles of Analytical Ultracentrifugation, the volume Sedimentation Velocity Analytical Ultracentrifugation: Discrete Species and Size-Distributions of Macromolecules and Particles describes the theory and practice of data analysis. Mathematical models for the sedimentation process and the evolution of detected signals are developed in a comprehensive framework, jointly with the description of current and historical strategies for how to extract from noisy experimental data the physical parameters of interest, such as size, mass, and shape, composition, and polydispersity of sedimenting particles. The methods are extensively illustrated, and supported with practical applications, as well as cross-references where to find the methods in the public domain software SEDFIT and SEDPHAT. The systems covered are discrete or polydisperse mixtures of sedimenting molecules or particles in dilute solution, such as proteins and other biomolecules and their stable complexes, man-made polymers, and nanoparticles, observed in different optical systems. These methods form the essential foundation for the analysis of dynamic interacting systems, which are covered in a separate volume.

A follow-up to the experimental and instrumental aspects described in Basic Principles of Analytical Ultracentrifugation, the volume Sedimentation Velocity Analytical Ultracentrifugation: Discrete Species and Size-Distributions of Macromolecules and Particles describes the theory and practice of data analysis. Mathematical models for the sedimentation process and the evolution of detected signals are developed in a comprehensive framework, jointly with the description of current and historical strategies for how to extract from noisy experimental data the physical parameters of interest, such as size, mass, and shape, composition, and polydispersity of sedimenting particles. The methods are extensively illustrated, and supported with practical applications, as well as cross-references where to find the methods in the public domain software SEDFIT and SEDPHAT. The systems covered are discrete or polydisperse mixtures of sedimenting molecules or particles in dilute solution, such as proteins and other biomolecules and their stable complexes, man-made polymers, and nanoparticles, observed in different optical systems. These methods form the essential foundation for the analysis of dynamic interacting systems, which are covered in a separate volume.

Sedimentation Equilibrium Analytical Ultracentrifugation

This book will fill a need among animal paleopathologists and animal forensic scientists for a text/atlas focused on lesions that commonly appear in skeletal remains. The text describes what is known about disease pathogenesis and occurrence in modern and historical settings and include evolutionary and comparative considerations. It is a stand-alone atlas on animal bone disease with images of lesions on the whole bone, which would facilitate understanding of bone disease and provide insights into disease processes. This book fills a unique niche - a text/atlases on comparative bone pathology that includes images of whole specimens.

This book will fill a need among animal paleopathologists and animal forensic scientists for a text/atlas focused on lesions that commonly appear in skeletal remains. The text describes what is known about disease pathogenesis and occurrence in modern and historical settings and include evolutionary and comparative considerations. It is a stand-alone atlas on animal bone disease with images of lesions on the whole bone, which would facilitate understanding of bone disease and provide insights into disease processes. This book fills a unique niche - a text/atlases on comparative bone pathology that includes images of whole specimens.Key selling features:<ul> <li>Illustrates lesions in animal skeletal remains - no other such reference exists</li> <li>Reviews the basic pathology and pathogenesis of animal bone diseases</li> <li>Provides a source of information on the historical and modern contexts associated with the occurrence of animal bone diseases</li> <li>Describes evolutionary susceptibilities of bone disease in animals</li> <li>Examines human comparative aspects of bone disease in animals</li> </ul>

Pathological Conditions in Animal Skeletal Remains

Calcium silicate hydrate, as the principal component of the hydration of Portland cement, has been the topic of intensive research over the past several years. An understanding of the nature of this hydration product at the nanoscale is essential for the strategic modification of conventional cement-based systems and the development of new materials with enhanced properties. This book will explore this topic and how to enhance concrete functionalities utilizing nanotechnology.

Developments in Cement-based Systems

Nanotechnology in Construction Materials

Food and Nutritional Toxicology, Second Edition

Pharmacy Education Series

The new edition of a bestseller, this book covers the principles of chemistry and biology necessary to understand drug action at the cellular level. The book places special emphasis on the chemical and physical properties of drugs, drug absorption and distribution, drug interactions with cellular receptors, drug metabolism and elimination, and the genetic basis for variations in drug response. The book includes revision and updates of chapters. It also includes new material on pharmacogenomics, cancer chemotherapies, and drug-receptor and drug-enzyme interactions.

The new edition of a bestseller, this book covers the principles of chemistry and biology necessary to understand drug action at the cellular level. The book places special emphasis on the chemical and physical properties of drugs, drug absorption and distribution, drug interactions with cellular receptors, drug metabolism and elimination, and the genetic basis for variations in drug response. The book includes revision and updates of chapters. It also includes new material on pharmacogenomics, cancer chemotherapies, and drug-receptor and drug-enzyme interactions.

Understanding Drug Actions and Reactions, Second Edition

Basic Pharmacology

Aortic Valve Repair provides a comprehensive summary on techniques developed during the first 500 cases of aortic ring annuloplasty. Aortic valve disease is usually surgically managed by aortic valve replacement, and it is well established in published literature regarding the long-term results, survival rate, durability of the protheses and reoperations rates. Over the past two decades, aortic valve repair (AVr) has evolved into a recognized surgical option for selected patients with aortic insufficiency or proximal aorta aneurysm. Studying the first 500 cases of aortic ring annuloplasty, the authors provide the most effective methods of leaflet and aortic root reconstruction to repair pathologies. Including original illustrations and videos, the book serves as an essential reference for cardiac surgeons in practice.

Aortic Valve Repair

The essential illustrated compendium of sauropod dinosaurs, from the towering Brachiosaurus to small, long-necked herbivoresThe Princeton Encyclopedia of Dinosaurs: Sauropods brings together every species of long-necked dinosaur known to have roamed the prehistoric world, with a dedicated entry for each species describing its key characteristics, taxonomic classification, location, and known remains along with a concise history of its discovery. Each species is beautifully brought to life with vivid illustrations and is supported by meticulously detailed diagrams of all known fossils. These visual aids enable readers to explore how scientists reconstruct these incredible creatures from fossilized remains. Whether you're curious about Brachiosaurus, Titanosaurus, or the multitude of less familiar sauropod species, this encyclopedia covers them all. The Princeton Encyclopedia of Dinosaurs is a comprehensive three-volume resource for anyone who is fascinated by dinosaurs. Packed with engaging dino facts and original, full-color reconstructions, drawings, and graphics, this one-of-a-kind encyclopedia strikes a perfect balance between depth and accessibility-detailed enough to captivate professionals yet clear and exciting enough for beginners eager to dive into the amazing lost world of the dinosaurs. The three volumes, which are available individually or as a set, are Theropods, Sauropods, and Ornithischians. Organized for easy reference, these books are perfect for casual browsing or in-depth study. Together, this encyclopedia invites dinosaur lovers of all ages to walk among the wonderous beasts of the Mesozoic era.

The Princeton Encyclopedia of Dinosaurs: Sauropods

Anatomy and Histology of the Pig

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