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"Explaining how evolution can account for the complexity of life is a significant question in biology. Whether or not complexity increases, what the mechanisms are that fuel this growth, and indeed even how we define complexity are difficult questions. In this book Christoph Adami draws on two strands of research - experimental evolution and information theory - to forward a mathematical theory that accounts for the evolution of complexity. While accounting for complexity is his primary goal, Adami also argues that information theory can do more for biology than just provide for a measure of complexity. As he argues, everything in biology uses information in one form or another, be it for communication (between cells, or organisms) or for prediction (via molecular as well as neural circuits). As a consequence, we can think of information theory as the unifying framework that allows us to understand complex systems, with biological life being only the prime example"--

Why information is the unifying principle that allows us to understand the evolution of complexity in nature More than 150 years after Darwin’s revolutionary On the Origin of Species, we are still attempting to understand and explain the amazing complexity of life. Although we now know how evolution proceeds to build complexity from simple ingredients, quantifying this complexity is still a difficult undertaking. In this book, Christoph Adami offers a new perspective on Darwinian evolution by viewing it through the lens of information theory. This novel theoretical stance sheds light on such matters as how viruses evolve drug resistance, how cells evolve to communicate, and how intelligence evolves. By this account, information emerges as the central unifying principle behind all of biology, allowing us to think about the origin of life—on Earth and elsewhere—in a systematic manner. Adami, a leader in the field of computational biology, first provides an accessible introduction to the information theory of biomolecules and then shows how to apply these tools to measure information stored in genetic sequences and proteins. After outlining the experimental evidence of the evolution of information in both bacteria and digital organisms, he describes the evolution of robustness in viruses; the cooperation among cells, animals, and people; and the evolution of brains and intelligence. Building on extensive prior work in bacterial and digital evolution, Adami establishes that (expanding on Dobzhansky’s famous remark) nothing in biology makes sense except in the light of information. Understanding that information is the foundation of all life, he argues, allows us to see beyond the particulars of our way of life to glimpse what life might be like in other worlds.

The Evolution of Biological Information

How Evolution Creates Complexity, from Viruses to Brains

A thoroughly updated new edition of the foundational reference on veterinary anesthesia and analgesia Veterinary Anesthesia and Analgesia: The Sixth Edition of Lumb and Jones is a fully updated revision to this comprehensive, authoritative reference to all aspects of veterinary anesthesia and pain management. Encompassing both scientific principles and clinical applications, the new edition adds new knowledge, techniques, and discussion of emerging issues throughout. Fourteen new chapters significantly expand the coverage of patient monitoring modalities and nociception and pain, while presenting new information on safety culture, infection prevention and control, biomedical engineering, and point-of-care ultrasound. Logically organized into sections, information on basic principles, pharmacology, specific body systems, and specific species is easy to access. Comparative anesthetic considerations for dogs and cats, horses, ruminants, swine, laboratory animals, free-ranging terrestrial mammals, marine mammals, reptiles, amphibians, fish, and birds are discussed. Chapters are devoted to anesthesia and pain management of common domestic species and patient populations, including updated chapters on local and regional anesthetic and analgesic techniques. A companion website offers video clips of point-of-care ultrasound techniques and pain assessment and scoring. Readers of Veterinary Anesthesia and Analgesia: The Sixth Edition of Lumb and Jones will also find: <ul><li>Significantly expanded coverage of patient monitoring, including new chapters devoted to anesthetic depth and electroencephalography, electrocardiography, blood pressure, ventilation, oxygenation, and anesthetic gas monitoring. </li><li>More in-depth coverage of respiratory physiology and pathophysiology, with new sections covering oxygen therapy, mechanical ventilation, anesthetic management considerations for bronchoscopy, intrathoracic procedures, including one-lung ventilation, and patients with respiratory disease. </li><li>Expanded coverage of pain physiology and pathophysiology, recognition and quantification of pain, and clinical pain management, including both pharmacologic and nonpharmacologic modalities. </li><li>A companion website incorporating video clips and example pain scoring sheets to complement the more than 500 images in the text itself. </li></ul> With its unparalleled multidisciplinary approach, Veterinary Anesthesia and Analgesia is a must-own volume for veterinary anesthesia specialists and researchers; specialists in other disciplines, including both small and large animal surgeons; practitioners; and students.

VETERINARY ANESTHESIA AND ANALGESIA

A thoroughly updated new edition of the foundational reference on veterinary anesthesia and analgesia

Veterinary Anesthesia and Analgesia: The Sixth Edition of Lumb and Jones is a fully updated revision to this comprehensive, authoritative reference to all aspects of veterinary anesthesia and pain management. Encompassing both scientific principles and clinical applications, the new edition adds new knowledge, techniques, and discussion of emerging issues throughout. Fourteen new chapters significantly expand the coverage of patient monitoring modalities and nociception and pain, while presenting new information on safety culture, infection prevention and control, biomedical engineering, and point-of-care ultrasound.

Logically organized into sections, information on basic principles, pharmacology, specific body systems, and specific species is easy to access. Comparative anesthetic considerations for dogs and cats, horses, ruminants, swine, laboratory animals, free-ranging terrestrial mammals, marine mammals, reptiles, amphibians, fish, and birds are discussed. Chapters are devoted to anesthesia and pain management of common domestic species and patient populations, including updated chapters on local and regional anesthetic and analgesic techniques. A companion website offers video clips of point-of-care ultrasound techniques and pain assessment and scoring.

Readers of Veterinary Anesthesia and Analgesia: The Sixth Edition of Lumb and Jones will also find:
* Significantly expanded coverage of patient monitoring, including new chapters devoted to anesthetic depth and electroencephalography, electrocardiography, blood pressure, ventilation, oxygenation, and anesthetic gas monitoring.
* More in-depth coverage of respiratory physiology and pathophysiology, with new sections covering oxygen therapy, mechanical ventilation, anesthetic management considerations for bronchoscopy, intrathoracic procedures, including one-lung ventilation, and patients with respiratory disease.
* Expanded coverage of pain physiology and pathophysiology, recognition and quantification of pain, and clinical pain management, including both pharmacologic and nonpharmacologic modalities.
* A companion website incorporating video clips and example pain scoring sheets to complement the more than 500 images in the text itself.

With its unparalleled multidisciplinary approach, Veterinary Anesthesia and Analgesia is a must-own volume for veterinary anesthesia specialists and researchers; specialists in other disciplines, including both small and large animal surgeons; practitioners; and students.

Veterinary Anesthesia and Analgesia, The 6th Edition of Lumb and Jones