Single Molecule Dynamics in Life Science

Advances in instrumentation over the last few years have established single molecule measurements as a major method in many biological laboratories. Exploiting the full power of such measurements is dependent on a good understanding of single molecule behavior and enzymology. In this first comprehensive resource on the topic, one of the world's most distinguished single molecule scientists has put together a team of pioneers in the field to show how to both set up and interpret a single molecule experiment. Following an introduction to single molecule measurements and enzymology, the authors consider molecular motors and mechanical properties before moving on to the applications themselves. Detailed discussions of studies on protein enzymes, ribozymes and nucleic acids are also included. Indispensable reading for a growing number of scientists.