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Rhythms of Speech and Language

Physiology, Cognition, Culture

The MIT Press Essential Knowledge series

Cannabinoids

Critical Approaches and Innovations in Language Teacher Education

Activism in Language Teaching and Language Teacher Education

Oxford Handbooks

The Oxford Handbook of Philosophy of Linguistics

El Bilinguismo en el Mundo Hispanohablante

How the Overdiagnosis Epidemic is Making Us Sick - THE SUNDAY TIMES BESTSELLER

The Age of Diagnosis

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Brain Imaging Essentials

The Deep Learning Revolution

Bloomsbury Advances in Critical Discourse Studies

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Handbook of Clinical Neurology

The evolution of neuroimmunotherapies with the concurrent progress in autoimmune neurology will introduce the book, followed by an update on "non-targeted" therapies highlighting the value of immunosuppressants, plasmapheresis, IVIg or hematopoietic bone marrow transplantation and their mode of action in autoimmune neurology. The new agents in each of these categories, along with biomarkers for therapeutic monitoring and the application of reliable scales in assessing response, will be covered. Chapters will discuss how neuroimmunotherapies work when key molecules and pathways associated with CNS or PNS tissue damage are targeted or inhibited. The volume will describe the approved agents targeting: 1) T-cell intracellular signaling pathways and molecules associated with antigen presentation; 2) B cells, B-cell trophic factors, and autoantibodies; 3) Fc receptor modulation; 4) complement; and 5) cytokines, cell adhesion and transmigration molecules. Didactic schemes and illustrations on how these drugs work in autoimmune neurological diseases will be provided in each chapter. The second part of the book will discuss the latest therapeutics for each major autoimmune neurological disease, aimed to provide a reliable, comprehensive and up-to-date source of information useful for clinical practice and education. Didactic and practical algorithms, a step-by step approach on how best to apply the most suitable therapies for a given state of the disease or proceed to escalation therapies will be provided. Treatment controversies and uncertainties will be authoritatively emphasized by scholars in each field. A chapter addressing potential immunotherapeutic approaches, now on the pipeline or on early trials, as future means of treating some neurodegenerative diseases will be included. Another chapter will cover the new and popular-although controversial -concept of treating autoimmune pain. The book discusses practical therapies with¿traditional immunosuppressants, steroids and IVIg. It describes targeted therapies with monoclonal antibodies or fusion proteins against B cells , T cells, complement, and FcRn, discussing what happens when key factors related to neurological autoimmunity are inhibited. The book provides a "how- to- do" approach for each of the major autoimmune diseases with algorithms and escalation therapies. Dedicated chapters will cover current therapies on encephalitis, NMOSD, Multiple sclerosis , autoimmune neuropathies, myopathies, neuromuscular junction disorders and neuroexcitability disorders like stiff person syndrome. The book is aimed for practitioners and academicians as a reliable and comprehensive source for applying neuroimmunotherapies and understanding their mechanisms.

Immunotherapies for Neurologic Diseases: Volume 214

From Basic to Applied Perspectives

The Handbook of Autobiographical Memory

Playing is an essential part of psychotherapy, and sandplay in particular allows for the development of an active tie between the therapist and the patient. This book analyses the elements that are introduced into therapy through sandplay: implicit memory, the embodied self and empathy, as well as the relationship that is created through the process of this type of therapy. Napoliello focuses on sandplay, but the use of the ideas here extends to the importance of activating a dimension of play in a patient as a way to bridge a link between the conscious and subconscious, on the importance of body language and using past experience to decipher the meaning of physical movements.

Play, alchemy and neuroscience

Sandplay and the Therapeutic Relationship

From Data to Analysis

Semantic Research

Rhythms of Speech and Language

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