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Gesamtkatalog

Catalogue complet

Practical Problems and Approaches in
Genetic Counseling

Practical Problems and Approaches in Genetic Counseling

Challenges in the Era of Genomic Medicine

Advances in Experimental Medicine and Biology

Reproductive Sciences in Animal Conservation

Time wants you dead. Not just you, but your friends, family, pets - everyone you've ever met...

'A beautifully written book about life and death: busts myths, explores the stories of science and history, and ultimately is rich and uplifting.' Dr Adam Rutherford

With over 17,000 known diseases affecting humans, and countless poisons, carcinogens and toxins in our environment, it's a miracle that our bodies manage to keep us alive. And that is, of course, if they don't betray us themselves, whether through cancers or autoimmune conditions.

Biomedical researcher Professor John Tregoning tells the unlikely story of how, against all odds, we manage to stay alive. Taking an organ-by-organ tour of the human body, Tregoning embarks on his own experimental quest, testing 'life-extending' diets and exercise regimes to separate fact from fad. Exploring the multitude of ways our bodies can kill us, from inherited genetic conditions, through heart attacks, arrythmias and angina, onto the delicate workings of the brain, Live Forever?&nbsp;offers compelling insight into how our bodies work, how we can best look after them - and ultimately live longer, healthier lives.

***

'I heartily recommend this deep dive into wellness... It turns out that none of us are getting out of here alive, but John has bravely put his mind and body on the line to discover the secrets of staying healthy and happy as we get older. A funny, fascinating and educative book.' Ben Willbond, co-creator of Ghosts

'The idea that a book about death and dying could be a delightful read seems ridiculous, and yet John Tregoning has pulled off this trick with humour, flair and elegance.' Nessa Carey, author of The Epigenetics Revolution

'An enjoyable and entertaining mixture of scientific facts about ageing and completely unscientific self-experimentation... recognizing that although none of us will live forever, there are ways we can improve our chances of living well while we are still around.' Dame Sarah Gilbert

A Curious Scientist’s Guide to Wellness, Ageing and Death

Live Forever?

Individual tumour molecular profiling and tacking dynamic evolution by treatment related selective pressure are crucial for clinical oncology. However, current tissue biopsy cannot represent spatial and temporal tumour heterogeneity due to sampling bias. 

Liquid biopsy is an alternative way of tissue biopsy since it can represent comprehensive molecular signature from multiple distinct lesions and real time tracking is feasible by repeated longitudinal assay during course of treatment.

This book describes current knowledge regarding pre-analytical issues including standardization of blood preparation, analytical variability, clinical application and regulatory agency approval issue, etc. Regarding targets in circulation, it focuses on circulating tumour cells (CTCs), circulating nucleic acid (ctDNA, cell free RNAs), extracellular vesicles, tumour educated platelets, and others (proteins, metabolites).

The book will be a rich source of information and instruction for oncologists and offers stimulating ideas on prospects for further progress in this field.

Current Status and Future Challenges

Liquid Biopsy for Cancer

This book provides an in-depth exploration of the history, development, and applications of gamma knife radiosurgery, with a particular focus on its proliferation and utilization across Asia. The narrative offers a country-by-country account, detailing the implementation and advancements of gamma knife radiosurgery in various Asian nations. This regional analysis highlights the unique contributions and challenges faced by each country in integrating this advanced neurosurgical technique. The second half of the text delves into the diverse clinical applications of gamma knife radiosurgery in Asia, discussing its effectiveness and evolving methodologies in treating a range of neurological conditions, from vestibular schwannoma and meningioma to Parkinson's disease and obsessive-compulsive disorder.

Asian Perspectives On Gamma Knife Surgery

Translational Epigenetics

Site Specific and Global Epigenomic Editing: Principles and Applications, Volume 33 highlights the expanding role that epigenetics plays in pathogenesis, the full range of sites for possible epigenetic modification, and the potential to target these sites to modulate disease progression. The book answers key questions, including which of the hundreds of epigenomic marks and features are relevant, and which are likely to serve a role in regulating gene expression, cell behavior and phenotypic outcomes. This volume is the first to provide a thorough, conceptual introduction to epigenetic regulation and a thorough accounting of sites for possible epigenetic edits and disease modulation. Included protocols and applied case studies examine early disease targets and likely pathways of therapeutic significance while also outlining common challenges in the field. The book addresses its topic in a comprehensive, but accessible manner, highlighting practical tools and burning questions remaining in the field to enable fresh research.

Principles and Applications

Site Specific and Global Epigenomic Editing: Volume 33

In this revolutionary book, Evie Kendal explores the potential that ectogenesis has to promote sexual equality in human reproduction and the role science fiction plays in imagining its realisation.

Reproductive Futures

Science Fiction and the Ethics of Artificial Wombs

The Clinics: Surgery

Pancreatic Cancer, An Issue of Surgical Oncology Clinics of North America: Volume 35-1

A thought-provoking deep dive into the global fertility industry and the commodification of the maternal bodyShould surrogacy be a paid service, an altruistic act - or even legal at all?Is it right that you can pay more for 'VIP' egg donors - and to view their photos?How much, if anything, should breastmilk cost - and who should be allowed to buy it?The global fertility industry is rapidly growing, hugely profitable and extremely morally complex. From egg freezing to black-market breastmilk, the maternal body has never been more commodified, yet we have never stopped to fully consider the ethical, emotional and economic implications.Through a combination of undercover journalism and compelling personal interviews - including a surrogate of 12 children, an international embryo courier and a man who buys breastmilk for his IBS - Alev Scott exposes how the IVF, surrogacy and milk industries operate around the world. In doing so, she considers the blurred line between exploitation and empowerment. Who should make money from the maternal body: only the women themselves, anyone or no one?Timely, thought-provoking and compelling, Cash Cow is an unmissable investigation into how desire, desperation and commerce intersect.

How the Maternal Body Became a Global Commodity – and the Hidden Costs for Women

Practical Problems and Approaches in Genetic Counseling

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