This volume provides insights into newly emerging developments in glia biology and focusing on the healthy nervous system. Driven by advances in genetics, transcriptomics, electrophysiological and imaging techniques, this volume bridges the gap between glia basic science and glia clinical research. The book provides an overview of glia biology, highlighting emerging technologies used to unravel the role of glial cells in specific brain functions. The book also discusses strategies using glia as a therapeutic target.