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Uher T: Mimics and Red Flags of Multiple
Sclerosis

Mimics and Red Flags of Multiple Sclerosis

Infolge einer neurologischen Erkrankung oder Verletzung stellen neben offenkundigen neurologischen Ausfällen und Hirnleistungsstörungen nicht selten Veränderungen im emotionalen Erleben und Verhalten der Patienten eine große Herausforderung dar. Das Buch gibt einen Überblick über ein verhaltensneurologisch und neuropsychologisch hochrelevantes Syndrom, das bei unzureichender diagnostischer Abklärung den Krankheits- und Behandlungsverlauf nachhaltig beeinträchtigt.Obwohl die definitorische Abgrenzung des Begriffs der Exekutivfunktionen nach wie vor als äußerst heterogen gilt, wird der Idee nachgegangen, das Konstrukt der Exekutivfunktionen als Bindeglied zwischen den einzelnen Funktionsebenen und damit als Kern einer hirnorganisch bedingten Persönlichkeitsveränderung zu betrachten.Das Buch wendet sich an Klinische Neuropsychologen, Fachärzte für Neurologie und Psychiatrie sowie Psychologische Psychotherapeuten. Der Inhalt&nbsp;Theoretische Überlegungen – Persönlichkeitsveränderungen im klinischen Kontext – Diagnostische Herausforderungen, Möglichkeiten und Grenzen – Erweiterungen diagnostischer und therapeutischer Konzeptionen Die AutorinDr. phil. Caroline Kuhn arbeitet seit über 20 Jahren als Neuropsychologin und Verhaltenstherapeutin. Sie leitet die Neuropsychologische Lehr- und Forschungsambulanz an der Universität des Saarlandes.

Diagnostik hirnorganisch bedingter Persönlichkeitsveränderungen

Verhaltensneurologische Störungen

Advances in Anatomy, Embryology and Cell Biology

This book reviews the role of exosomes in both male and female reproduction organs, focusing on the impact of extracellular vesicles on gamete maturation and embryo development.
Fertilization is a complex process involving the fusion of two functionally matured gametes. Maturation of spermatozoa and/ or oocyte dependents on sophisticated, but highly regulated events during gamete transit in the reproductive tracts. Sperm maturation occurs within the epididymis, of which segmented regions provide a distinct microenvironment to facilitate stage-wise maturation processes. Although oocyte maturation occurs within the ovary, communication between oocyte and its surrounding granulosa/cumulus cells is vital for the development and the resumption of meiotically arrested oocytes. Once the oocyte is released from the ovary, the oviductal epithelium continues to facilitate sperm-oocyte interaction to achieve fertilization. Increasing evidence suggests that the uterus, the site for embryo development, also carries out epithelia- embryo communication via uterosomes throughout the pregnancy. All above-mentioned processes rely on orchestrated communications between reproductive tract epithelia and gametes.
In this book, we aim to summarize the origin of secretory vesicles from the reproductive tract and their functions for gamete and embryo development. It is written for researchers, physicians and medical students working in the field of reproductive science or with an interest in extracellular vesicles research.

Origin, Functions and Perspective

Extracellular Vesicles in Reproduction

Comprehensive ENT

This book provides a comprehensive and up-to-date overview of general information, along with an evaluation of diagnostic and therapeutic options for individuals suffering from otologic diseases. Covering fundamental sciences, clinical applications of otology treatments, and the latest research, it is designed to aid physicians in making well-informed decisions about patient care management.Divided into seven parts, the book addresses topics such as hearing reconstruction and its acoustic impact, cochlear implants, brainstem implants, genetic causes of hearing loss, including prevention and rehabilitation, sudden deafness, autoimmune inner ear disease, and the molecular basis of otosclerosis. Contributors also explore the contemporary clinical application of genetics and available testing for hearing loss.This volume will serve as an invaluable resource for otolaryngologists, head and neck surgeons, audiologists, neurologists, neurosurgeons, and residents, offering a comprehensive guide to enhance their understanding and practice.

Otology Updates

Von neurophysiologischen Grundlagen über Befund und Techniken bis hin zu komplexen PNF-Mustern – dieses umfassende Praxis- und Lehrbuch führt Sie Schritt für Schritt durch alle Aspekte der Propriozeptiven Neuromuskulären Fazilitation (PNF). Es unterstützt Sie dabei, diese etablierte therapeutische Methode fundiert zu erlernen und sicher in der Praxis anzuwenden.Es behandelt die Kernprinzipien des PNF-Konzepts, darunter die philosophischen Ansätze, das ICF-Modell, motorisches Lernen und weitere relevante Aspekte. Die funktionellen Einsatzmöglichkeiten der PNF-Muster werden praxisnah und anschaulich vermittelt.Mit über 640 detaillierten Abbildungen veranschaulicht das Fachbuch die wichtigsten Techniken und Behandlungsschritte. Zahlreiche Fallbeispiele, klinische Hinweise sowie Wiederholungsfragen am Ende eines jeden Kapitels fördern nicht nur Ihr Verständnis, sondern auch Ihre Anwendungskompetenz im therapeutischen Alltag.Diese vollständig überarbeitete 6. Auflage enthält neue Fallsbeispiele und erweiterte Kapitel zu Hemiplegie, Skoliose und Parkinson. Außerdem enthält sie aktualisierte Informationen zur IPNFA®, die neueste wissenschaftliche Literatur und Beiträge eines internationalen Teams erfahrener IPNFA®-Instruktor*innen.Über die Autor*innenDominiek Beckers schloss 1975 sein Masterstudium in Physiotherapie ab und verfügt über mehr als 40 Jahre Erfahrung in der Rehabilitation und als IPNFA®-Instruktor.Mônica Cilento ist Professorin an der Katholischen Universität von Petrópolis, Brasilien. Sie verfügt über 39 Jahre Erfahrung mit neurologische Patient*innen und ist seit 2004 IPNFA®-Instruktorin. Seit 2000 ist sie außerdem IPNFA®-Vertreterin in Brasilien und ehemalige Präsidentin der IPNFA®.Agnieszka Stępień hat einen MSc und einen PhD &nbsp;(2023) von der Józef-Piłsudski-Universität in Warschau, Polen. Sie verfügt über 32 Jahre Erfahrung als Physiotherapeutin und ist auf Kinder und Skoliose spezialisiert. Seit 2023 ist sie Senior-Instruktorin bei IPNFA®.Shin Seung Sub verfügt über 27 Jahre als Physiotherapeut und behandelt vor allem neurologische Patient*innen. Er erwarb 2012 seinen Doktortitel in Physiotherapie und leitet in Seoul seine Privatpraxis Dr. Fizio®. Seit 2022 ist er IPNFA® Advanced Instructor.Youngkeun Woo ist Physiotherapeut in Korea und Professor an der Jeonju University. Er verfügt über umfassende klinische Erfahrung in der Behandlung neurologischer Patient*innen – sowohl in Allgemeinkrankenhäusern als auch in Privatpraxen und universitären Einrichtungen. Seit 2023 ist er als IPNFA® Advanced Instructor tätig.Math Buck war seit 1972 als Physiotherapeut tätig und arbeitete über vier Jahrzehnte hinweg mit Patient*innen mit Rückenmarksläsionen. Seit 1984 war er IPNFA®-Instruktor und Mitbegründer der IPNFA®. Math Buck ist am 21. September 2024 verstorben.

Eine Anleitung in Bildern

PNF in der Praxis

This comprehensive volume provides balanced and easily readable chapters on contemporary topics around discourse production in patients with neurogenic disorders. Discourse broadly refers to a unit of language longer than a single sentence, typically used in a spoken or written format to express ideas, feelings, and opinions or to interact with others. As the field of research in speech-language pathology, aphasia and related neurogenic disorders, and clinical decision-making to manage neurogenic impairments is rapidly expanding, there has been an increased focus on discourse analysis and therapy to enable patients to speak well again. Various user groups and people with lived experience (e.g., aphasia, dementia, traumatic brain injury, right hemisphere damage, etc.) are also increasingly focused on the impact of neurogenic impairments on domains of conversation and changes in language skills beyond the smaller linguistic components of single words and sentences that are traditionallysupported by speech-language therapy.The first part of this book details and discusses the basic principles, historical perspectives (history and developmental milestones), neural basis, and recent evolutions and advancement of discourse analysis in speakers with acquired communication disorders. The second part of the book outlines and illustrates current methods for discourse elicitation and analysis across different clinical populations. Recent leaps forward in technology that can assist in the recording, processing, and analysis of discourse will be highlighted. The final part of book reviews and summarizes key developments of various evidenced-based training strategies, interventions, and treatment programs, as well as utilization of innovative technology to clinically improve neurogenic disordered discourse.This is an ideal guide for researchers, clinicians, and students in the field of communication sciences and disorders, speech and language therapy, gerontology, (neuro-)linguistics, psychology, and related fields in clinical medicine.

A State-of-the-Art, Contemporary Approach

Spoken Discourse Impairments in the Neurogenic Populations

Advances in Experimental Medicine and Biology

The book presents key topics at the forefront in breast development and cancer research in chapters authored by leading scientists in the field.The chapters provide a basis for understanding major concepts, model systems, cells of origin and heterogeneity in human breast development and cancer. The book builds on this understanding to guide readers through the cellular and molecular basis of breast cancer and the most important signaling pathways. Finally, the book describes mechanisms of metastasis and cancer immunity, and treatment options and resistance to therapy.It is targeted at young scientists and early career researchers and provides an overview of current topics in breast cancer research. Each chapter includes key learning points, boxes and conclusions to highlight the most important information. This book will interest anyone who wants to learn about the main areas of breast cancer research and the most important recent advances.

From Cellular Heterogeneity and Molecular Mechanisms to Therapy

A Guide to Breast Cancer Research

Current Clinical Neurology

The field of muscular dystrophies has expanded significantly with the discovery of the genetic defects and protein products underlying these disorders. New treatments such as antisense oligonucleotides and siRNAs and gene therapies are now in clinical application and in trials. As clinical trials increase, outcome measurement becomes very important, and more validated tools are being developed. This book provides a comprehensive review of these disorders. Clinical features, diagnostic testing including genetic testing of these disorders, the basis and utility of genetic testing, and the basis of genetic therapies are all covered in detail. This book will provide neuromuscular neurologists, general neurologists, and neuromuscular fellows with a much needed update in the field.

Principles and Practice of the Muscular Dystrophies

Current Topics in Behavioral Neurosciences

This volume brings together pre-clinical and clinical research on topics highly relevant to the development and improvement of our understanding of Alzheimer's disease (AD). The combination of both research areas will appeal to a broad range of researchers from basic scientists to neurologists. The topics cover both established and more recent areas of research on the underlying causes of this disease which are still not fully understood more than 100 years after its first description by Alois Alzheimer. This broad perspective demonstrates how research into AD is evolving along with considering clinical aspects of the disease. The chosen contributors are well-placed to provide expert views on these topics. The book is divided into 2 sections, pre-clinical research and clinical research. While each section contains unique topics, there are also topics common to both areas such as Down Syndrome, considerations of diversity and behavioural and neurobiological symptoms of dementia to provide a wider perspective on these topics. The inclusion of Down Syndrome demonstrates the reverse translation of knowledge from the clinic to laboratory-based neurobiology. The two main sections are then further subdivided into groups for related topics. The broad overview of this book will encourage researchers to pursue bold and innovative research to expand knowledge of this complex neurodegenerative disease and to improve its detection, diagnosis, treatment, and management.

Neurobiology of Alzheimer's Disease

This book offers an in-depth exploration of the most significant cranial surgical approaches in neurosurgery, blending tradition and hands-on experience. Designed for neurosurgery residents, fellows, and practicing neurosurgeons committed to lifelong learning, it serves as both a technical guide and a source of inspiration for excellence in the field. Organized into 21 meticulously structured chapters, the book covers a wide spectrum of procedures, from commonly performed surgeries to complex skull base and posterior fossa approaches. Each chapter is rooted in over a century of neurosurgical evolution, combining established literature with the authors’ personal refinements and procedural insights. The practical component is enriched by videos recorded from a surgeon’s point of view using innovative technology, including action video cameras and microscope-mounted smartphones, with AI-generated narration to enhance clarity.
Neurosurgical Approaches Video Atlas&nbsp;addresses the gap between formal literature and the experiential knowledge passed from mentor to mentee. It invites readers to pursue excellence through continuous observation, study, and adaptation, recognizing that the journey toward mastery in neurosurgery is ongoing.

Neurosurgical Approaches Video Atlas

Exercise-Induced Leg Pain in Sport

Fachwissen Pflege

Pflegewissen Neurologie und Neurochirurgie

This book fills the need for a detailed examination of the role of Endocannabinoid System in all the body's main organ systems and how dysregulation of that system can lead to disease. It serves as an in-depth analysis of the thousands and thousands of studies on the Endocannabinoid System within the medical literature. It covers the many diseases that can result from Endocannabinoid system dysfunction, ranging from metabolic syndrome to anxiety disorders to osteoporosis.&nbsp;The book is written primarily for medical providers and those with a science background.

Diseases of the Endocannabinoid System

Mimics and Red Flags of Multiple Sclerosis

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