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Fentiman I: Male Breast Cancer

Male Breast Cancer

The Story of GLP-1: A Historical Journey in the Treatment of Diabetes and Obesity is a critically acclaimed account detailing the groundbreaking discovery of the hormone GLP-1, narrated by the award-winning scientist Professor Jens Juul Holst, along with co-authors Professor Sten Madsbad, Professor Jens Meldgaard Bruun, and Mads Krogsgaard Thomsen, CEO of the Novo Nordisk Foundation. GLP-1 is the hormone found in weight loss medications and diabetes treatments such as Ozempic and Wegovy. The discovery of GLP-1 has significantly transformed treatment options for individuals with type 2 diabetes and obesity, offering benefits that include improved blood glucose regulation and substantial weight loss, while also lowering the risk of related complications. Professor Jens Juul Holst, MD, DMSc, is among the world's leading diabetes researchers, having pioneered the discovery of GLP-1 in the 1980s. In this book, we follow the historical research journey that led to the identification of this hormone, which now signifies a paradigm shift in the management of diabetes and obesity. "The Story of GLP-1: A Historical Journey in the Treatment of Diabetes and Obesity" narrates the rising rates of obesity and diabetes, underscoring a critical public health issue, even in light of considerable progress in treatment alternatives. While traditional approaches, such as low-calorie diets, have shown potential for short-term weight loss, maintaining that loss has proven difficult. Efforts to achieve better blood sugar control have not consistently translated into reduced complications or improved patient outcomes, as demonstrated by extensive international studies. However, the introduction of new diabetes medications, particularly those based on glucagon-like peptide-1 (GLP-1), such as liraglutide and semaglutide, has marked a significant breakthrough. These medications not only improve blood sugar levels but also promote substantial weight loss and reduce cardiovascular complications, offering hope for better management of obesity and diabetes. Despite these promising results, challenges remain regarding accessibility and affordability of these treatments, raising important societal questions about who should receive them and how they should be funded. The author's involvement in the discovery and development of GLP-1 provides a unique perspective on the historical and physiological context of these advancements, making this book a valuable resource for understanding the complexities of metabolic diseases and the evolution of treatment options.

A Historical Journey in the Treatment of Diabetes and Obesity

The Story of GLP-1

First published in 1991, Human Sectional Anatomy set new standards for the quality of cadaver sections and accompanying radiological images. Now in its fifth edition, this unsurpassed quality remains and is further enhanced by additional new material including new examples using the most up-to-date imaging technologies.

Atlas of Body Sections, CT and MRI Images

Human Sectional Anatomy

No-RT and Beyond RT

Individualized Treatment Strategies in the Radiotherapy Era

This book introduces new trend in medical treatment of hair loss and discusses advanced technologies in the management of hair loss.&nbsp;Regenerative medicine has rapidly growing and gaining in popularity to treat hair loss in men and women and also in conjunction with hair restoration surgery. Tricho test as an aid in selecting who will benefit the medical therapy so physician can use this as the guideline for treatment. FUE device with hybrid punch continue to advance in its technology to minimize follicular transection and speed the extraction rate. Advance in medical therapy of hair loss is more toward the combination of multi drug that need to be discussed regarding the result and complication. The combination of FUT and FUE is gaining more popularity and need to clarify its use and technique.

Emerging Technologies in Alopecia Treatment

Principles and Practice of Interventional Pulmonology

Endocrinology

Neuroendocrine Neoplasia

Individual tumour molecular profiling and tacking dynamic evolution by treatment related selective pressure are crucial for clinical oncology. However, current tissue biopsy cannot represent spatial and temporal tumour heterogeneity due to sampling bias. 

Liquid biopsy is an alternative way of tissue biopsy since it can represent comprehensive molecular signature from multiple distinct lesions and real time tracking is feasible by repeated longitudinal assay during course of treatment.

This book describes current knowledge regarding pre-analytical issues including standardization of blood preparation, analytical variability, clinical application and regulatory agency approval issue, etc. Regarding targets in circulation, it focuses on circulating tumour cells (CTCs), circulating nucleic acid (ctDNA, cell free RNAs), extracellular vesicles, tumour educated platelets, and others (proteins, metabolites).

The book will be a rich source of information and instruction for oncologists and offers stimulating ideas on prospects for further progress in this field.

Current Status and Future Challenges

Liquid Biopsy for Cancer

Griffbereit - prägnant – übersichtlich&nbsp;Der Kitteltaschen-Ratgeber&nbsp;für die Arztpraxis&nbsp;zur Therapie von Infektionskrankheiten<ul><li>Die wichtigsten Antibiotika und Antimykotika: Spektrum - Dosierung - Nebenwirkungen</li><li>Zahlreiche Tabellen geordnet nach Substanzen, Erregern und Indikationen </li><li>Antibiotikagabe bei Schwangerschaft/Stillzeit </li><li>Kostensparende und umweltschonende Hygieneratschläge für die Arztpraxis </li><li>Hygienefragen der täglichen Praxis: Kopflausbefall, Magensonde ... </li></ul>&nbsp;NEU: Alternative antiinfektiöse Therapie erweitert

mit Hygieneratschlägen

Antibiotika in der Praxis 2021 - 2022

Current Status and Phytomedicine

Polycystic Ovary Syndrome (PCOS)

Metabolic Memory: Past, Present and Future Implications delves into the emerging concept of metabolic memory, exploring how our body's metabolic processes retain a 'memory' of past experiences and how this impacts our current and future health. Drawing on the latest scientific research this book aims to bridge the gap between complex scientific concepts and their practical implications for everyday health and wellness. Metabolic memory has profound implications for understanding chronic diseases, particularly diabetes, cardiovascular diseases, and obesity. Despite its significance, there is a lack of comprehensive resource that make this information accessible to both professionals and the general public. This book fills that gap, providing a detailed yet understandable exploration of how past metabolic states influence present and future health outcomes.

Past, Present and Future Implications

Metabolic Memory

Genome Editing and Nanotechnology-Based Treatment for Breast Cancers delves deeply into the multifaceted nature of breast cancer. It begins with a thorough introduction to the disease, detailing its histological and molecular subtypes and then moves on to explain methods for early detection and imaging techniques. The book also explores various treatment options, focusing on innovative technologies like genome editing and nanotechnology. In its nine sections, the book probes the elements that contribute to breast cancer metastasis and discusses the potential of genome editing tools for creating tailor-made drugs. Users will find this to be a crucial resource for researchers, graduate students in cancer research and bioinformatics, oncologists, and anyone seeking to expand their understanding of the field.

Genome Editing and Nanotechnology-Based Treatment for Breast Cancers

Imaging in Medical Diagnosis and Therapy

Proton Radiography and Tomography for Medical Applications

Proton Imaging Technology

Male Breast Cancer

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