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Immunoassays

Methods, Troubleshooting and Regulatory Requirements

Basic, Applied and Clinical Aspects

Systemic Lupus Erythematosus

Immunological Insights and Emerging Therapeutics in Medical Mycology summarizes the current knowledge on interactions between host cells and human fungal pathogens and explains how certain immune defects lead to vulnerability to fungal infection. Chapters focus on immune response to such fungal infections as candidiasis, aspergillus, cryptococcosis, mucormycosis, pneumocystis.This title provides a basis for further study on antifungal immunity by enhancing understanding of antifungal immune responses. Further, this title offers new insights from the host immune response, improving understanding of disease pathogenesis and informing novel prophylactic and therapeutic approaches to fungal infections.

Immunological Insights and Emerging Therapeutics in Medical Mycology

Reproductive Immunology

Immunological Aspects of Preterm Birth: Phenotypes of Preterm Birth, Immune Mechanisms, and Pathway Forward bridges reproductive immunology of preterm birth to subtypes, phenotypes, and bedside prevention and treatment. The book reviews the role of the different immune mechanisms during pregnancy that lead to preterm birth, along with the fetal programming effects that are connected to maternal immune activation. In addition, it discusses immune cells and their products and cytokines and chemokines as central for the success of the pregnancy. While our knowledge on the role of immune cells and the inflammatory process in preterm birth has grown exponentially in the last 10 years, connecting basic science to clinical science and the development of new therapeutics has not progressed as rapidly. This book assists researchers in understanding the basic immunologic mechanisms and inflammatory processes associated with preterm birth and fills an urgent need for the development of therapeutics in this space.

Immunological Aspects of Preterm Birth

IoT-WSN-DT Based Medical Systems and Nanotechnology for Smart Cancer Care explores the latest advances in nanotechnology, artificial intelligence, Internet of Medical Things (IoMT), digital twin, and wireless sensor networks for real-time cancer care, enabling efficient decision-making and treatment. The book examines how data from medical nanosensors can be integrated with the technology of digital twins for cancer forecasting and monitoring, providing accessible smart insights via remote and mobile devices. By combining the strengths of smart nanotechnology, IoT-based platforms, WSN technologies, and DT, a powerful medical system can be developed for smart cancer care. This system can help in early diagnosis, targeted drug delivery, real-time monitoring, and personalized treatment, ultimately improving patient outcomes.

IoT-WSN-DT Based Medical Systems and Nanotechnology for Smart Cancer Care

Immunology for Medical Students provides concise yet comprehensive information for medical students about the basic science of the human immune system, and how to apply this to clinical practice. The book provides a detailed overview of how the immune system works, covers physiology, innate and adaptive immunity and the immune system in health and disease. Readers will learn how to assess a patient with an immune problem and understand from first principles the diagnosis and management of immune disorders. This popular book is an ideal companion for medical school courses and has been fully updated to include the latest science on immunotherapies.<ul><li>Clear and concise - designed with the needs of busy medical students in mind - just the right amount of detail for your course</li><li>Covers the latest scientific and clinical knowledge in the field</li><li>Detailed illustrations help the reader grasp the concepts of immunology</li><li>Detailed clinical cases demonstrate real-world applications</li><li>Technical boxes point out important scientific advances</li><li>End-of-chapter checklists of learning points facilitate review</li><li>An enhanced eBook version is included with purchase. The eBook allows you to access all the text, figures and references, with the ability to search, customise your content, make notes and highlights, and have content read aloud</li></ul><ul><li>Updates in basic science</li><li>New immunotherapies added e.g. CAR-T</li><li>Updates on inborn errors of immunity and acquired immune disorders</li></ul>

Immunology for Medical Students

Astrophysics and Space Science Library

This comprehensive introductory overview describes the emission of radiation (X-rays to radio) and the winds of host stars and how they control the past, present, and future evolution of an exoplanet. The book focuses on topics that are critically important for understanding exoplanet atmospheres but are often posed without a comprehensive and detailed understanding of the host star and its effects on the exoplanet. Although both stars and exoplanets are usually studied in isolation, in this book they are treated as an integrated system. Whether or not an exoplanet can retain its atmosphere and the chemical composition of the atmosphere depends critically on the strength, time dependence, and spectral energy distribution of the host star's radiation, flares, coronal mass ejections, and wind, which are described in detail in the book. The book describes the roles played by magnetic fields in the coronae and chromospheres of host stars that tie together stellar active phenomena with major effects on exoplanet atmospheres.In the era of JWST and very sensitive ground- and space-based instruments, a critical topic is the noise imposed on radial velocity measurements and transit photometry and spectroscopy by the host star's activity and variability that fundamentally limit our understanding of exoplanet properties. This topic is addressed in detail in the book.This book is written primarily for graduate students and researchers who are studying exoplanet atmospheres and habitability, but who may not have a background in the physics and phenomenology of host stars. The book could serve as a reference book for graduate level classes on exoplanets. Nonspecialists with a scientific background should also find this text a valuable resource for understanding the critical issues of contemporary exoplanet research.This new edition of “Host Stars and their Effects on Exoplanet Atmospheres" is a major revision of the existing book in the following ways:<ul><li>It includes a new discussion of how stellar noise fundamentally limits our understanding of exoplanet atmospheres</li><li>It demonstrates in detail how stellar activity acts as fundamental driver of exoplanet atmosphere evolution</li><li>It provides an outlook on how the field of exoplanet atmospheres and bio-astrophysics is being driven by powerful new telescopes and instruments</li><li>It extensively updates many chapters, in particular concerning host star extreme- and far-ultraviolet emission, stellar winds, stellar surface structures, the effects of space weather on exoplanets, and provides a realistic evaluation of habitability taking into account the evolution of host star activity.</li></ul>

An Introductory Overview

Host Stars and their Effects on Exoplanet Atmospheres

Advances in Cancer Research

Primary Brain Tumors in Adults: Advances in Mechanistic Understanding, Evaluation, and Management: Volume 166

Vaccinology and Immunizations is a thorough resource on the immune system, the history of vaccines, vaccine preparation, the process of vaccine approval, and the prevention and eradication of diseases. It also includes chapters on vaccine safety and errors, and complete information on pediatric and adult immunizations. There is also discussion on elderly immunology and immunization for people who are seeking to travel abroad, as well as timely information about COVID-19. Its focus on the innate and adaptive defense systems of the body will ensure understanding of human immunity and how immunizations are effective. There is a variety of available titles related to vaccinology and immunizations, but many are now outdated. Vaccinology and Immunizations provides a new, updated resource that is widely needed, and will be welcomed by students of undergraduate, graduate and master level in vaccinology or immunology, and would also be of interest to nurses, researchers, and pharmacists.

Vaccinology and Immunizations

Subcellular Biochemistry

The book&nbsp;Neuroepigenetic Mechanisms in Health and Disease&nbsp;provides insight into mechanisms of epigenetic control, focusing on molecular, cellular and integrative aspects of neurobiology. Here, leading investigators in the field discuss in each chapter landmark scientific discoveries and recent advances in (neuro) epigenetics.Whereas some chapters concentrate in overviewing basic epigenetic mechanisms and the power of epigenome editing, other sections of the book discuss epigenetic control during learning and memory as well as in diverse brain related alterations, including neurodegenerative and rare neurologic diseases, and psychiatric disorders. In addition, the book covers relevant topics for modern human societies, including how drug abuse, environmental enrichment and meditation can influence brain function through epigenetic mechanisms. This book aims to serve as a useful source for junior scientists to first learn about the topic, as well as to more experienced researchers that seek for a broader view of this rapidly growing field that is beyond their area of specialization.

Neuroepigenetics Mechanisms in Health and Disease

Immunology is highly valued by medical students and medical science students everywhere for demystifying a complex and rapidly developing area of medicine. The book integrates basic and clinical immunology, providing up-to-date information that links the laboratory with clinical practice. It covers all the core immunology concepts that students need for their coursework, including immunity, immune responses, defence against infectious agents, and hypersensitivity. The book's structure makes it easy to understand, presenting immunology in the order that aligns with typical teaching methods. Ideal for USMLE and MLA preparation, it comes complete with accompanying online animations, cases studies, and self-assessment. Carefully structured layout - easy to follow and identify high yield informationExplains the building blocks of the immune system - cells, organs and major receptor molecules - as well as initiation and actions of the immune response, especially in a clinical contextMore learning opportunities online, including USMLE-style questions and clinical cases - ideal for exam revision and practiceAnimations offer a visual overview of immunological conceptsAn enhanced eBook version is included with purchase. The eBook allows you to access all the text, figures and references, with the ability to search, customise your content, make notes and highlights, and have content read aloudMore case studiesThoroughly updated coverage of: VirusesTransplantationVaccinationImmunodeficienciesCheckpoint inhibitorsAnti-malarial vaccinesAntibody and cell-based therapies

Immunology

Advances in Immunology

Advances in DNA and mRNA-Based Strategies for Cancer Immunotherapy: Part A: Volume 165

Space and Society

One of the more contentious questions to emerge into scientific prominence has been whether life is prevalent in the cosmos. Although there are many factors that shape this debate, one of the most overlooked yet crucial rests on the temporal organization in biotic systems.In this work the author investigates the compatibility and incompatibility between the thermodynamic arrow of time indicative of abiotic structure, and the temporal organization so characteristic of biotic processes and uses it to explore the origins of life here and elsewhere. Far from a minor problem, the author argues that the temporal organization in biotic systems plays a key role in shaping not only the prevalence of life, but also in grounding the scientific theories we use to explain the universe and the moral concepts that will anchor our exploration of the larger cosmos.

Investigating the Conceptual, Ethical and Cosmological Implications of Astrobiology

The Temporal Organization of Life

Immunoassays

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