Functional Groups in Biochemistry: Tailored Chemistry in Biological Contexts includes detailed mechanisms of reactions, focusing on functional groups and their chemical/biochemical properties that determine the biological functions of macromolecules, a connection often overlooked or under-emphasized in standard textbooks. It provides a deeper understanding of the governing principles of biochemical reactions, as well as how key chemical and biochemical reactions are thought to occur at the atomic/molecular level. With an emphasis on common themes that govern biochemical reactivity, Functional Groups in Biochemistry fills the gap between organic/bioorganic chemistry and biochemistry texts.