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Miljana Z. Jovandaric: Fetal Programming

Fetal Programming

The Connection between Nutrition and Disease

Integrated Science

This book seeks to represent the main concepts and theories related to psychoneuroimmunology with the aim of their application in clinical settings and formation of novel theories to further elucidate the mutual connection of the psyche and the physiology of humans' body. Psychoneuroimmunology, as an integration of popular research fields such as psychology, immunology, neurology, and neuroscience, is a perfect example of interdisciplinary and transdisciplinary studies that could potentially result in developing alternative diagnostic tools and treatment strategies besides facilitating the understanding of the pathophysiology of some conditions that might not properly be understood with a single point of view. Considering the stressful lifestyle and the high prevalence of neuropsychiatric, metabolic, and immune-related disorders, psychoneuroimmunology could be the path to the management of these conditions and reduction of the burden of the diseases.

Volume 2: Interdisciplinary Approaches to Diseases

PsychoNeuroImmunology

Cholesterol Metabolism in Aging and Disease provides in-depth coverage on the mechanistic intersection between the aging process and cholesterol metabolism. The book covers the discovery of cholesterol, its biochemistry, and how it came to have such a prominent role in aging and disease. Important areas such as cholesterol biosynthesis and cellular cholesterol homeostasis are described in detail. Technological advancements in computational modeling are also discussed to help improve our understanding of cholesterol metabolism so that new therapeutic avenues are opened to help treat age-related diseases associated with the dysregulation of this key system. This is a must have reference for students and researchers interested in, or working in, various aspects of aging. In addition, it is ideal for clinician researchers and gerontologists.

Cholesterol Metabolism in Aging and Disease

This biochemistry textbook has been revised and expanded for its second edition. It provides biotechnologists and bioprocess engineers with valuable insights into Technical Biochemistry, showing how technology and biology can complement each other.

The authors aim to present a textbook for bioengineering students, linking biological concepts with technical and engineering challenges. It focuses on biochemical principles in natural product biosynthesis and their biotechnological and bioprocess engineering pathways.

Content:

<ul>
	<li>Application of biochemistry in medicine, pharmacy, and engineering</li>
	<li>Photosynthesis - The chemistry of light</li>
	<li>Carbohydrate metabolism - Sugars as energy carriers</li>
	<li>Amino acids and peptides - Proteins as biocatalysts</li>
	<li>Carbohydrates, lipids, and proteins - Building blocks for technical and pharmaceutical substances</li>
	<li>Biosyntheses of primary and secondary metabolism</li>
	<li>Natural product biosynthesis - Secondary metabolites</li>
</ul>

Target Audience:

<ul>
	<li>Students of bioprocess engineering, biotechnology, pharmacy, and chemistry</li>
	<li>Biologists, biotechnologists, process engineers, pharmacists, and chemists with a focus on biotechnology</li>
</ul>

The Authors: 
Oliver Kayser, professor of Technical Biochemistry at the Technical University of Dortmund, specializes in the biosynthesis of cannabinoids in yeast. 
Nils Averesch, a bioengineering PhD with a focus on metabolic engineering, leads a research group at Stanford University exploring bioproduction of biomaterials using greenhouse gases. 
 
The translation was done with the help of artificial intelligence. A subsequent human revision was done primarily in terms of content.&nbsp; This book is a translation of an original German edition. The translation was done with the help of artificial intelligence (machine translation by the service DeepL.com). A subsequent human revision was done primarily in terms of content, so that the book will read stylistically differently from a conventional translation.

The Biochemistry and Industrial Use of Natural Products

Technical Biochemistry

Dieses leicht zugängliche Buch bietet den interessierten Lesenden einen Überblick über die wichtigsten Merkmale hormoneller Erkrankungen, deren Diagnose und Behandlung. Von Gigantismus und Kleinwuchs bis hin zu polyzystischem Ovarialsyndrom, Schilddrüsenüberfunktion und vielen weiteren Themen – erklärt es auch, was Endokrinologie-Spezialistinnen und -Spezialisten tun und warum, wenn sie Patientinnen und Patienten diagnostizieren und behandeln.

Verfasst von einem ausgewiesenen Experten auf diesem Gebiet, bietet jedes Kapitel eine kurze Einführung in die jeweilige hormonelle Erkrankung, mit Informationen zu Symptomen, Diagnose und Behandlung in einem leicht verständlichen Frage-und-Antwort-Format. Einfache, aber präzise Diagramme veranschaulichen die Inhalte. Das Buch klärt wichtige Fragen und hilft Patientinnen und Patienten dabei, fundierte Entscheidungen zu treffen. Nicht zuletzt behandelt es aktuelle Themen aus der Praxis der Endokrinologie sowie spannende historische Fakten. Es ist ein absolutes Muss für alle, die sich für die faszinierende Welt der Hormone und ihrer Erkrankungen interessieren.

Ein Leitfaden

Hormonelle Erkrankungen

Exploring Immunogenetic Pathways

Type 2 Diabetes Mellitus

The Clinics: Internal Medicine

Thyroid Cancer Update, An Issue of Endocrinology and Metabolism Clinics of North America: Volume 54-3

Handbook of Clinical Neurology

The evolution of neuroimmunotherapies with the concurrent progress in autoimmune neurology will introduce the book, followed by an update on "non-targeted" therapies highlighting the value of immunosuppressants, plasmapheresis, IVIg or hematopoietic bone marrow transplantation and their mode of action in autoimmune neurology. The new agents in each of these categories, along with biomarkers for therapeutic monitoring and the application of reliable scales in assessing response, will be covered. Chapters will discuss how neuroimmunotherapies work when key molecules and pathways associated with CNS or PNS tissue damage are targeted or inhibited. The volume will describe the approved agents targeting: 1) T-cell intracellular signaling pathways and molecules associated with antigen presentation; 2) B cells, B-cell trophic factors, and autoantibodies; 3) Fc receptor modulation; 4) complement; and 5) cytokines, cell adhesion and transmigration molecules. Didactic schemes and illustrations on how these drugs work in autoimmune neurological diseases will be provided in each chapter. The second part of the book will discuss the latest therapeutics for each major autoimmune neurological disease, aimed to provide a reliable, comprehensive and up-to-date source of information useful for clinical practice and education. Didactic and practical algorithms, a step-by step approach on how best to apply the most suitable therapies for a given state of the disease or proceed to escalation therapies will be provided. Treatment controversies and uncertainties will be authoritatively emphasized by scholars in each field. A chapter addressing potential immunotherapeutic approaches, now on the pipeline or on early trials, as future means of treating some neurodegenerative diseases will be included. Another chapter will cover the new and popular-although controversial -concept of treating autoimmune pain. The book discusses practical therapies with¿traditional immunosuppressants, steroids and IVIg. It describes targeted therapies with monoclonal antibodies or fusion proteins against B cells , T cells, complement, and FcRn, discussing what happens when key factors related to neurological autoimmunity are inhibited. The book provides a "how- to- do" approach for each of the major autoimmune diseases with algorithms and escalation therapies. Dedicated chapters will cover current therapies on encephalitis, NMOSD, Multiple sclerosis , autoimmune neuropathies, myopathies, neuromuscular junction disorders and neuroexcitability disorders like stiff person syndrome. The book is aimed for practitioners and academicians as a reliable and comprehensive source for applying neuroimmunotherapies and understanding their mechanisms.

Immunotherapies for Neurologic Diseases: Volume 214

Strüngmann Forum Reports

This open access book provides an interdisciplinary perspective on energy metabolism in the brain and body in neuropsychiatric disorders and suggests future research directions.
Multiple lines of evidence indicate that energy metabolism is aberrant in the body and brain in individuals with major neuropsychiatric disorders such as schizophrenia, mood disorders, and neurodegenerative disorders. Emerging therapeutic interventions aim to improve outcomes in many of these common and severe disorders. To foster interdisciplinary dialogue and to promote informed applications in research, medicine, and public health, the Ernst Strüngmann Forum convened scholars from diverse fields to examine the role of energy metabolism in brain function, the bidirectional association between metabolism in the brain and body, and the future therapeutic potential of treatment interventions that improve metabolism in people with psychiatric disorders.
Synthesizing the interdisciplinary perspectives that emerged from these discussions, the book is organized in four sections:
<ul>
<li>Role of Metabolism in Brain Function</li>
<li>Metabolic Abnormalities in Neuropsychiatric Disorders</li>
<li>Systemic Metabolic Aspects of Neuropsychiatric Disorders</li>
<li>Metabolism-Based Therapies</li>
</ul>
This volume offers insights to researchers and clinicians working in basic, translational, and clinical research in neurology and psychiatry pertinent to mitochondrial function, energy metabolism, human physiology, and treatment development.

Metabolic Neuropsychiatry

Endocrine and Metabolic Emergencies in Emergency Medicine, An Issue of Endocrinology and Metabolism Clinics of North America: Volume 55-1

The Bermuda Triangle

Thyroid, Diabetes and Osteoporosis

This standard work provides all physicians with confidence regarding execution and evaluation of endocrinological function tests. It supports efficient diagnostics, yields valuable results, and ensures reliable assessments in endocrinology, diabetology, gynecology, urology, andrology, pediatrics, internal medicine. The content is aligned with the recommendations of national and international professional societies.This book comprises more than 200 hormonal parameters, function tests as well as validated scoring and grading systems. Basic knowledge regarding diagnostic methods in radiological and nuclear medicine as well as genotype-phenotype correlations are summarized. All parameters are rigorously correlated to age, gender, BMI, phase of life, menstrual cycle, and medication by presenting 174 tables and 66 figures.Detailed and practice-relevant, you will receive a quick overview of indications, contraindications, side effects, test preparation, framework conditions, specific action guidelines for test execution, secure evaluation of results with detailed cut off values, as well as practical tips and potential pitfalls.The 5th edition has been completely updated and expanded to include topics such as "troubleshooting" in immunoassays, paraneoplastic syndromes, screening for malnutrition, basal and stimulated copeptin, metyrapone test, macimorelin test, and digital diabetes parameters (CGM).The translation was done with the help of artificial intelligence. A subsequent human revision was done primarily in terms of content. This book is a translation of an original German edition. The translation was done with the help of artificial intelligence (machine translation by the service DeepL.com). A subsequent human revision was done primarily in terms of content, so that the book will read stylistically differently from a conventional translation.

Dynamic Endocrine Testing

Current Status and Phytomedicine

Polycystic Ovary Syndrome (PCOS)

Fetal Programming

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