Digitally Disrupted Space: Proximity and New Development Opportunities for Regions and Cities develops an analytical framework of the key structural elements in relation to the digital space and its impact on existing spatial interactions at a regional and urban level. The book puts forth the argument that the digital space is a new form of space acting complementary to existing spatial structures and creating novel interactions between and/or within them. It explores how digital space enhances connected intelligence by combining knowledge-intensive activities, cooperation between organizational and institutional actors, and smart environments of knowledge creation and diffusion. Academics and researchers will find insights into how cities and regions can adopt this new developmental paradigm; how to organize connected intelligence within regional and urban environments; and how to sustain productivity, resilience and inclusion through the use of digital space. Digital transformation managers in the public sector and entrepreneurs in private organizations can leverage the opportunities offered from this transition process, not only by identifying actions and strategies for boosting their productivity, but also for making them more resilient during socio-economic, environmental and health crises.