During the last three decades research interests were dedicated to the new subclass of organic ligands - cyanoximes. With 38 different R groups the most abundant is the family of mono-cyanoximes, followed by 7 bis-cyanoximes that include aromatic and aliphatic spacers, and lately 2 tris-cyanoximes - a tripod type of ligands - was obtained and characterized. These simple low molecular weight organic molecules represent series of new excellent ampolydentate ligands for coordination chemistry. Currently 48 cyanoximes are known, and there were more than two hundreds cyanoxime complexes synthesized and studied using a variety of different spectroscopic methods and X-ray analysis. Methods of syntheses, stereochemistry of cyanoximes ligands, their structures and properties, as well as the most interesting coordination compounds are described in this book, as well as a broad spectrum of practical applications of both cyanoximes, and their metal complexes. Cyanoximes: Chemistry, Coordination and Organometallic Compounds and their Applications contains information about practical aspects of presented compounds including established structure-biological activity trends which may be very useful for discovery of new drug candidates that further may be developed into drugs. This book contains vast information about the use of cyanoximes as small molecules ligands in coordination, bioinorganic and organometallic chemistry. It also presents structural chemistry of these compounds and shows their most interesting spectroscopic properties, coupled with practical aspects of their chemistry.