A current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction is detailed in our Neurobiology of Addiction series, each volume addressing a specific area of addiction. Cannabis, Volume 5 in the Neurobiology of Addiction series, explores the molecular, cellular and systems in the brain responsible for both nicotine and marijuana addiction. This volume includes thorough descriptions of the physiological effects and behavioral effects of nicotine and marijuana addiction. The authors clearly define the neurobiological effects into three distinct steps: Binge/Intoxication Stage, Withdrawal/Negative Affect Stage and last the Preoccupation/Anticipation Stage.